Results 1 to 10 of about 435,892 (214)

A dodecylamine derivative of cyanocobalamin potently inhibits the activities of cobalamin-dependent methylmalonyl-CoA mutase and methionine synthase of Caenorhabditis elegans

FEBS Open Bio, 2014
In this study, we showed that cyanocobalamin dodecylamine, a ribose 5′-carbamate derivative of cyanocobalamin, was absorbed and accumulated to significant levels by Caenorhabditis elegans and was not further metabolized.
Tomohiro Bito, Yukinori Yabuta, Tsuyoshi Ichiyanagi, Tsuyoshi Kawano, Fumio Watanabe   +4 more
doaj   +1 more source

Vitamin B12 – a scoping review for Nordic Nutrition Recommendations 2023

Food & Nutrition Research, 2023
Vitamin B12 (cobalamin) is essential for normal metabolic function, and even moderate deficiency of this vitamin has negative health effects. Vitamin B12 is found in animal foods, and as vegetarian diets are increasingly popular in Western countries, one
Anne-Lise Bjørke-Monsen, Vegard Lysne
doaj   +1 more source

Hereditary intrinsic factor deficiency in China caused by a novel mutation in the intrinsic factor gene—a case report

BMC Medical Genetics, 2020
Background Hereditary intrinsic factor deficiency is a rare disease characterized by cobalamin deficiency with the lack of gastric intrinsic factor because of gastric intrinsic factor (GIF) mutations.
Jing Ruan, Bing Han, Junling Zhuang, Miao Chen, Fangfei Chen, Yuzhou Huang, Wenzhe Zhou   +6 more
doaj   +1 more source

Serum cobalamin and methylmalonic acid concentrations in juvenile dogs with parvoviral enteritis or other acute enteropathies

Journal of Veterinary Internal Medicine, 2023
Background Low serum cobalamin concentrations have been associated with ileal malabsorption in dogs with chronic enteropathy. Increased serum methylmalonic acid (MMA) concentrations indicate cobalamin deficiency on a cellular level.
Michael Hung, Justin Heinz, Jӧrg M. Steiner, Jan Suchodolski, Jonathan Lidbury   +4 more
doaj   +1 more source

Analysis of the causes of vitamin B12 deficiency in different age groups - a review of the literature

Journal of Education, Health and Sport, 2022
Introduction and purpose  Vitamin B12 plays an important role in the process of erythropoiesis and the proper functioning of the nervous system. Its source for humans is food, in particular meat, eggs and shellfish.
Adrianna Nieciecka, Kornelia Kędziora-Kornatowska, Magdalena Lamch, Monika Jabłońska, Natalia Błasik, Agata Wójcik   +5 more
doaj   +1 more source

An update on cobalamin deficiency in adults [PDF]

QJM, 2009
Cobalamin (vitamin B12) deficiency is particularly common in the elderly (>65 years of age), but is often unrecognized because of its subtle clinical manifestations; although they can be potentially serious, particularly from a neuropsychiatric and hematological perspective.
Dali-Youcef, N., Andres, E.
openaire   +3 more sources

COBALAMIN DEFICIENCY

The Professional Medical Journal, 2016
Objectives: The present study aims to evaluate the serum cobalamin inHelicobacter pylori (H. pylori) infected patients. Study Design: Case control study. Place andDuration: Department of Medicine, Isra University Hospital Hyderabad from March 2013- April2014.
Shumaila Shaikh, Azhar Memon, Muhammad Atif Ata, Haji Khan Khoharo   +3 more
openaire   +2 more sources

Review: State of the knowledge on the importance of folates and cobalamin for dairy cow metabolism

Animal, 2023
Synthesis of B vitamins by the rumen microbiota is usually sufficient to avoid the appearance of clinical deficiency symptoms in dairy cows under normal feeding conditions.
C.L. Girard, M. Duplessis
doaj   +1 more source

Behavioral alterations are associated with vitamin B12 deficiency in the transcobalamin receptor/CD320 KO mouse.

PLoS ONE, 2017
Vitamin B12 (cobalamin) deficiency is prevalent worldwide and causes megaloblastic anemia and neurologic deficits. While the anemia can be treated, the neurologic deficits can become refractive to treatment as the disease progresses.
Kaveri Arora, Jeffrey M Sequeira, Alejandro I Hernández, Juan M Alarcon, Edward V Quadros   +4 more
doaj   +1 more source

Cobalamin and folate status in 6 to 35 months old children presenting with acute diarrhea in Bhaktapur, Nepal.

PLoS ONE, 2014
BackgroundCobalamin and folate are essential micronutrients and are important in DNA and RNA synthesis, cell proliferation, growth, hematopoiesis, and cognitive function.
Manjeswori Ulak, Ram K Chandyo, Ramesh K Adhikari, Pushpa R Sharma, Halvor Sommerfelt, Helga Refsum, Tor A Strand   +6 more
doaj   +1 more source