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The Many Faces of Cobalamin (Vitamin B12) Deficiency

Mayo Clinic Proceedings: Innovations, Quality & Outcomes, 2019
Although cobalamin (vitamin B12) deficiency was described over a century ago, it is still difficult to establish the correct diagnosis and prescribe the right treatment.
Bruce H.R. Wolffenbuttel, H. Wouters, M. R. Heiner-Fokkema, M. M. van der Klauw   +3 more
semanticscholar   +1 more source

Cofactor Selectivity in Methylmalonyl Coenzyme A Mutase, a Model Cobamide-Dependent Enzyme. [PDF]

, 2019
Cobamides, a uniquely diverse family of enzyme cofactors related to vitamin B12, are produced exclusively by bacteria and archaea but used in all domains of life.
Mok, Kenny, Park, Jong, Quanstrom, Kathryn, Sokolovskaya, Olga, Taga, Michi, Tran, Jennifer   +5 more
core   +1 more source

Pernicious Anemia Associated Cobalamin Deficiency and Thrombotic Microangiopathy: Case Report and Review of the Literature

Case Reports in Medicine, 2017
A 43-year-old Hispanic male without significant previous medical history was brought to emergency department for syncope following a blood draw to investigate a 40 lbs weight loss during the past 6 months associated with decreased appetite and ...
Farhanah Yousaf, B. Spinowitz, C. Charytan, M. Galler   +3 more
semanticscholar   +1 more source

Pernicious anemia is a common cause of cobalamin deficiency-caused megaloblastic anemia in Hainan, China

Hematology
Background Pernicious anemia (PA) is believed to be highly prevalent in Western countries but has rarely been reported in China. The study explores whether PA, an autoimmune disease, is an uncommon cause of cobalamin (vitamin B12) deficiency anemia in ...
Meixiao Shen, Xiansheng Luo, Cuiyun Wu, Juan Wang, Zhiming Wang, Meiqing Lei   +5 more
doaj   +1 more source

Serum Cobalamin and Methylmalonic Acid Concentrations in Hyperthyroid Cats Before and After Radioiodine Treatment

Journal of Veterinary Internal Medicine, 2016
Background Hyperthyroidism, the most common endocrine disorder in cats, has been associated with low serum cobalamin concentrations. Whether this is a functional cobalamin deficiency of clinical importance has not been assessed.
B.M. Geesaman, W.H. Whitehouse, K.R. Viviano   +2 more
doaj   +1 more source

Cobalamin deficiency and pathogenesis of neurological disorders

Вестник медицинского института «Реавиз»: Реабилитация, врач и здоровье, 2021
The brief review deals with the specific value of B vitamins for the nervous system, the mechanisms of transport and metabolic functions of cobalamin, pathogenetic theories related to vitamin B12 deficiency such as canonical biochemical theory and the ...
A. V. Pereshein, S. V. Kuznetsova, T. E. Potemina   +2 more
doaj   +1 more source

Cobalamin C Deficiency–Associated Pigmentary Retinopathy [PDF]

JAMA Ophthalmology, 2015
A12-year-oldgirlhadpoorvision inbotheyessincechildhood.Visual acuitywas counting fingerswith associatednystagmus. Theelectroretinogramwasnonrecordable.Hermedicalhistorywasnotableforfailuretothrive,methylmalonicaciduria,andhomocystinuria.Genetictesting revealedmutations in theMMACHC gene.
José María, Garcia-Gonzalez, Ashley E, Neiweem, Michael A, Grassi   +2 more
openaire   +2 more sources

Evaluating Red Patches and Burning Mouth Symptoms as Oral Biomarkers in Cobalamin Deficiency: A Comparative Study

Plasmatology
Background Vitamin B12 (cobalamin) deficiency can manifest through various nonspecific oral symptoms. Early diagnosis is crucial but challenging due to subtle and progressive clinical features.
Sanjay Chikkarasinakere Jogigowda MDS, Karthikeya Patil MDS, Varusha Sharon Christopher MDS, Namrata Suresh MDS, Shilpa Padar Shastry MDS, Vidya Gowdappa Doddawad MDS   +5 more
doaj   +1 more source

Understanding the gastrointestinal tract of the elderly to develop dietary solutions that prevent malnutrition [PDF]

, 2015
Although the prevalence of malnutrition in the old age is increasing worldwide a synthetic understanding of the impact of aging on the intake, digestion, and absorption of nutrients is still lacking.
Bordoni, Alessandra, Dupont, Didier, Gille, Doreen, Kachal, Josefa, Peyron, Marie-Agnès, Pinto, Paula, Rémond, Didier., Santos, Claudia Nunes Dos, Shahar, Danit R., Tomás-Cobos, Lidia, Vergères, Guy, Walther, Barbara   +11 more
core   +4 more sources

Vitamin B12 Deficiency in Neurological Disorders of Older Adults: Etiology, Diagnostics, Treatment

Российский журнал гериатрической медицины
One of the common problems associated with aging is vitamin B12 (cobalamin) deficiency. According to some reports, it is present in every third person over the age of 60.
M. A. Cherdak, E. A. Mkhitaryan
doaj   +1 more source