Results 21 to 30 of about 465,921 (178)

A study into the cobalamin-dependent methionine synthase reactivation mechanism in corynebacterium glutamicum [PDF]

, 2009
PhDMethionine is one of the seven essential amino-acids for humans and is also used in feed supplements, predominantly for poultry and felines. Thus there is commercial interest in producing this nutrient. The final step in the biological synthesis of
Burton-Smith, Raymond Nathaniel
core   +3 more sources

The relationship between serum cobalamin, folic acid, and homocysteine and the risk of post-cardiac surgery delirium

Neuropsychiatric Disease and Treatment, 2019
Maryam Vahdat Shariatpanahi,1 Aynaz Velayati,2 Seyed Ali Jamalian,3 Mehdi Babevaynejad,4 Zahra Vahdat Shariatpanahi21Department of Psychiatry, Faculty of Medicine, Tehran Medical Sciences, Islamic Azad University, Tehran, Iran; 2National Nutrition and ...
Vahdat Shariatpanahi M, Velayati A, Jamalian SA, Babevaynejad M, Vahdat Shariatpanahi Z   +4 more
doaj   +1 more source

Neurological disorders in vitamin B12 deficiency [PDF]

Терапевтический архив, 2019
The review discusses thesteps of vitamin B12 metabolism and its role in maintaining of neurological functions. The term "vitamin B12 (cobalamin)" refers to several substances (cobalamins) of a very similar structure. Cobalamin enters the body with animal
Ch S Pavlov, I V Damulin, Yu O Shulpekova, E A Andreev   +3 more
doaj   +1 more source

Review of cobalamin status and disorders of cobalamin metabolism in dogs

Journal of Veterinary Internal Medicine, 2020
Disorders of cobalamin (vitamin B12) metabolism are increasingly recognized in small animal medicine and have a variety of causes ranging from chronic gastrointestinal disease to hereditary defects in cobalamin metabolism.
Stefanie Kather, Niels Grützner, Peter H. Kook, Franziska Dengler, Romy M. Heilmann   +4 more
doaj   +1 more source

The Biochemical Basis of Cobalamin Deficiency [PDF]

Mayo Clinic Proceedings, 1994
In this report, our goal was to summarize the current knowledge of the biochemical basis for the impaired DNA synthesis and neuropathy associated with vitamin B12 deficiency.We reviewed the pertinent literature and our clinical experience with cobalamin deficiency.Studies have established that the megaloblastic hematopoiesis associated with vitamin B12
A, Tefferi, R K, Pruthi
openaire   +2 more sources

A single-center cross-sectional study on the clinical profile of pancytopenia and a novel scoring system for megaloblastic anemia

Apollo Medicine, 2022
Background: Our study tries to identify the main culprits causing pancytopenia and its typical clinical presentation, along with the clinical and hematological profile of megaloblastic anemia (MGA)-induced pancytopenia, in a tertiary care hospital in ...
Sanjaykumar Somsingbhai Rathwa, Darshankumar Manubhai Raval, Shashwat Mallik, Shahin Khan   +3 more
doaj   +1 more source

Dietary deficiency of cobalamin presented solely as schizoaffective disorder in a lacto-vegetarian adolescent

Indian Journal of Psychological Medicine, 2015
Cobalamin is an important nutrient. It is not synthesized in human body and supplied only in nonvegetarian diet. Its deficiency reported with range of psychiatric disorders. Only four pediatric cases have been reported as psychiatric disorders.
Somashekarappa Dhananjaya, Narayana Manjunatha, Rajashekaaiah Manjunatha, Seetharamarao Udaya Kumar   +3 more
doaj   +1 more source

A dodecylamine derivative of cyanocobalamin potently inhibits the activities of cobalamin-dependent methylmalonyl-CoA mutase and methionine synthase of Caenorhabditis elegans

FEBS Open Bio, 2014
In this study, we showed that cyanocobalamin dodecylamine, a ribose 5′-carbamate derivative of cyanocobalamin, was absorbed and accumulated to significant levels by Caenorhabditis elegans and was not further metabolized.
Tomohiro Bito, Yukinori Yabuta, Tsuyoshi Ichiyanagi, Tsuyoshi Kawano, Fumio Watanabe   +4 more
doaj   +1 more source

Vitamin B12 – a scoping review for Nordic Nutrition Recommendations 2023

Food & Nutrition Research, 2023
Vitamin B12 (cobalamin) is essential for normal metabolic function, and even moderate deficiency of this vitamin has negative health effects. Vitamin B12 is found in animal foods, and as vegetarian diets are increasingly popular in Western countries, one
Anne-Lise Bjørke-Monsen, Vegard Lysne
doaj   +1 more source

An update on cobalamin deficiency in adults [PDF]

QJM, 2009
Cobalamin (vitamin B12) deficiency is particularly common in the elderly (>65 years of age), but is often unrecognized because of its subtle clinical manifestations; although they can be potentially serious, particularly from a neuropsychiatric and hematological perspective.
Dali-Youcef, N., Andres, E.
openaire   +3 more sources