Results 11 to 20 of about 465,921 (178)

Cobalamin deficiency, hyperhomocysteinemia, and dementia

Neuropsychiatric Disease and Treatment, 2010
Steven F Werder1,21Kansas University School of Medicine – Wichita, Wichita, KS, USA; 2Community Health Center of Southeast Kansas, Pittsburg, KS, USAIntroduction: Although consensus guidelines recommend checking serum B12 in patients with ...
Steven F Werder
doaj   +5 more sources

Cobalamin deficiency resulting in a rare haematological disorder: a case report [PDF]

Journal of Medical Case Reports, 2009
Introduction We present the case of a patient with a cobalamin deficiency resulting in pancytopaenia, emphasizing the importance to define, diagnose and treat cobalamin deficiency. Case presentation A 52-year-old man from the Democratic Republic of Congo
Chapuis Thomas M, Favrat Bernard, Bodenmann Patrick   +2 more
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Relationship between cobalamin deficiency and delirium in elderly patients undergoing cardiac surgery

Neuropsychiatric Disease and Treatment, 2015
Utkan Sevuk,1 Erkan Baysal,2 Nurettin Ay,3 Yakup Altas,2 Rojhat Altindag,2 Baris Yaylak,2 Vahhac Alp,3 Ertan Demirtas4 1Department of Cardiovascular Surgery, Diyarbakir Gazi Yasargil Education and Research Hospital, Diyarbakir, 2Department of Cardiology,
Sevuk U, Baysal E, Ay N, Altas Y, Altindag R, Yaylak B, Alp V, Demirtas E   +7 more
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Cobalamin deficiency and pathogenesis of neurological disorders [PDF]

Вестник медицинского института «Реавиз»: Реабилитация, врач и здоровье, 2021
The brief review deals with the specific value of B vitamins for the nervous system, the mechanisms of transport and metabolic functions of cobalamin, pathogenetic theories related to vitamin B12 deficiency such as canonical biochemical theory and the ...
A. V. Pereshein, S. V. Kuznetsova, T. E. Potemina   +2 more
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Pernicious anemia is a common cause of cobalamin deficiency-caused megaloblastic anemia in Hainan, China

Hematology
Background Pernicious anemia (PA) is believed to be highly prevalent in Western countries but has rarely been reported in China. The study explores whether PA, an autoimmune disease, is an uncommon cause of cobalamin (vitamin B12) deficiency anemia in ...
Meixiao Shen, Xiansheng Luo, Cuiyun Wu, Juan Wang, Zhiming Wang, Meiqing Lei   +5 more
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The retention of cobalamin by the liver in the cobalamin-deficient rat

Clinical Science, 1985
1. The effect of cobalamin deficiency on whole body cobalamin content and its turnover was examined in the rat. Quantitative and qualitative changes in hepatic cobalamin were also followed and the effect of deficiency on the turnover of this cobalamin was determined in the isolated perfused liver. 2.
Owens, J.A., Scott, J.S.D., Cooksley, W.G.E.   +2 more
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Gene identification for the cblD defect of vitamin B12 metabolism [PDF]

, 2008
Background Vitamin B12 (cobalamin) is an essential cofactor in several metabolic pathways. Intracellular conversion of cobalamin to its two coenzymes, adenosylcobalamin in mitochondria and methylcobalamin in the cytoplasm, is necessary for the ...
Rosenblatt, D S, Suormala, T, Stucki, M, Newbold, R F, Coelho, D, Fowler, B, Lerner-Ellis, J P   +6 more
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New insights into the pathophysiology of cobalamin deficiency

Trends in Molecular Medicine, 2006
Cobalamin-deficient (Cbl-D) central neuropathy in the rat is associated with a locally increased expression of neurotoxic tumour necrosis factor-alpha (TNF-alpha) and a locally decreased expression of neurotrophic epidermal growth factor (EGF). These recent findings suggest that cobalamin oppositely regulates the expression of TNF-alpha and EGF, and ...
G. Scalabrino, M. Peracchi
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Cutaneous hyperpigmentation and cobalamin deficiency [PDF]

British Journal of Haematology, 2016
An exclusively breastfed five-month-old female was referred with anaemia, pallor and hyperpigmented genitalia and inner thighs (top). She was also lethargic, irritable and showed failure to thrive. Laboratory studies revealed a macrocytic anaemia with haemoglobin concentration (Hb) 73 g/l (normal range 95‒140), mean corpuscular volume (MCV) 104 fl (85 ...
Machado, R, Furtado, F, Kjöllerström, P, Cunha, F   +3 more
openaire   +4 more sources

Cobalamin and folate status in women during early pregnancy in Bhaktapur, Nepal

Journal of Nutritional Science, 2021
The demand for cobalamin (vitamin B12) and folate is increased during pregnancy, and deficiency during pregnancy may lead to complications and adverse outcomes. Yet, the status of these micronutrients is unknown in many populations.
Catherine Schwinger, Shakun Sharma, Ram K. Chandyo, Mari Hysing, Ingrid Kvestad, Manjeswori Ulak, Suman Ranjitkar, Merina Shrestha, Laxman P. Shrestha, Adrian McCann, Per M. Ueland, Tor A. Strand   +11 more
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