Results 41 to 50 of about 435,892 (214)

Vitamin B-12 deficiency stimulates osteoclastogenesis via increased homocysteine and methylmalonic acid [PDF]

, 2009
The risk of nutrient deficiencies increases with age in our modern Western society, and vitamin B(12) deficiency is especially prevalent in the elderly and causes increased homocysteine (Hcy) and methylmalonic acid (MMA) levels.
Bravenboer, N., Vaes, Bart L T, Vaes, B.L.T., Everts, V., Wilma T. Steegenga, Bravenboer, Nathalie, Steegenga, W.T., Lute, Carolien, Carolien Lute, de Groot, L.C.P.G.M., Müller, M.R., Henk J. Blom, de Groot, C.P.G.M., Muller, M., Dhonukshe-Rutten, R.A.M., de Groot, Lisette C P G M, Dhonukshe-Rutten, R.A., Bart L. T. Vaes, Teun J. de Vries, Blom, Henk J, Nathalie Bravenboer, Groot, L.C.P.G.M. de, de Vries, Teun J, Müller, Michael, Everts, Vincent, Rosalie A. Dhonukshe-Rutten, Michael Müller, de Vries, T.J., Lisette C. P. G. M. de Groot, Dhonukshe-Rutten, Rosalie A, Steegenga, Wilma T, Groot, C.P.G.M., de, Lute, C., Vries, T. J., Blom, H.J., Everts, V, Vries, T.J., de, Vincent Everts   +37 more
core   +2 more sources

Response of Human Glioblastoma Cells to Vitamin B12 Deficiency: A Study Using the Non-Toxic Cobalamin Antagonist

Biology, 2021
The most important biological function of vitamin B12 is to accomplish DNA synthesis, which is necessary for cell division. Cobalamin deficiency may be especially acute for rapidly dividing cells, such as glioblastoma cells.
Zuzanna Rzepka, Jakub Rok, Mateusz Maszczyk, Artur Beberok, Justyna Magdalena Hermanowicz, Dariusz Pawlak, Dorota Gryko, Dorota Wrześniok   +7 more
doaj   +1 more source

Systemic Scedosporium prolificans infection in an 11-month-old Border collie with cobalamin deficiency secondary to selective cobalamin malabsorption (canine Imerslund-Gräsbeck syndrome) [PDF]

, 2017
An 11-month-old Border collie presented collapsed and continued to deteriorate rapidly despite supportive treatment. The dog had a history of failure to thrive and recurring respiratory infection.
Mugford, A, K. Erles, Leeb, T, Leeb, T., Barfield, D, Erles, K, Barfield, D M, T. Leeb, Kook, P H, P. H. Kook, Kook, Peter H; https://orcid.org/, D. Barfield, A. Mugford   +12 more
core   +1 more source

Cobalamin Deficiency Can Mask Depleted Body Iron Reserves [PDF]

, 2015
Vitamin B12 deficiency impairs DNA synthesis and causes erythroblast apoptosis, resulting in anaemia from ineffective erythropoiesis. Iron and cobalamin deficiency are found together in patients for various reasons.
Solmaz, Soner, Ozdogu, Hakan, Boga, Can
core   +1 more source

Serum Cobalamin and Methylmalonic Acid Concentrations in Hyperthyroid Cats Before and After Radioiodine Treatment

Journal of Veterinary Internal Medicine, 2016
Background Hyperthyroidism, the most common endocrine disorder in cats, has been associated with low serum cobalamin concentrations. Whether this is a functional cobalamin deficiency of clinical importance has not been assessed.
B.M. Geesaman, W.H. Whitehouse, K.R. Viviano   +2 more
doaj   +1 more source

Trace Elements Genetics: A Potential Role in Treatment‐Resistant Major Psychoses and Related Traits?

American Journal of Medical Genetics Part B: Neuropsychiatric Genetics, EarlyView.
ABSTRACT Trace elements are pivotal to key biological processes, with possible effects on psychopathology. We investigated the hypothesis of shared genetic factors between trace elements levels, treatment resistance and related traits. We used genome‐wide summary statistics for trace elements blood concentration, treatment‐resistant depression (TRD ...
Chiara Fabbri, Alessandro Serretti, Marco Menchetti, Benedetta Vai, Francesco Benedetti, Lidia Fortaner‐Uyà, Concetta Crisafulli   +6 more
wiley   +1 more source

Evaluating Red Patches and Burning Mouth Symptoms as Oral Biomarkers in Cobalamin Deficiency: A Comparative Study

Plasmatology
Background Vitamin B12 (cobalamin) deficiency can manifest through various nonspecific oral symptoms. Early diagnosis is crucial but challenging due to subtle and progressive clinical features.
Sanjay Chikkarasinakere Jogigowda MDS, Karthikeya Patil MDS, Varusha Sharon Christopher MDS, Namrata Suresh MDS, Shilpa Padar Shastry MDS, Vidya Gowdappa Doddawad MDS   +5 more
doaj   +1 more source

Helicobacter pylori and cobalamin deficiency

Clinical and Laboratory Haematology, 2006
We have read with interest Maktouf et al.’s letter about the etiological role of deficiencies of cobalamin or folate in megaloblastic anemia. In this large prospective series, they investigated 478 patients with megaloblastic changes in bone marrow smears and reported the demographic, biological and clinical findings in cobalamin-deficient patients and
Kürflat, Kaptan, Cengiz, Beyan, Ahmet, Ifran   +2 more
openaire   +2 more sources

Vitamin B12 Deficiency in Neurological Disorders of Older Adults: Etiology, Diagnostics, Treatment

Российский журнал гериатрической медицины
One of the common problems associated with aging is vitamin B12 (cobalamin) deficiency. According to some reports, it is present in every third person over the age of 60.
M. A. Cherdak, E. A. Mkhitaryan
doaj   +1 more source

An on-line solid phase extraction procedure for the routine quantification of urinary methylmalonic acid by liquid chromatography-tandem mass spectrometry [PDF]

, 2010
Background: The goal of this study was to develop and to validate an improved isotope-dilution-liquid chromatography-tandem mass spectrometry (LC-MS/MS) method for the quantification of methylmalonic acid (MMA) in urine.
Michael Vogeser, Lorenzl, Stephan, Stephan Lorenzl, Fabian Kirchhoff, Vogeser, Michael, Kirchhoff, Fabian   +5 more
core   +1 more source