Results 51 to 60 of about 465,921 (178)

Cobalamin deficiency in dogs and cats [PDF]

, 2018
Cobalamin is a member of the B-group of vitamins and a cofactor for metabolic processes like nucleic acid synthesis, amino acid synthesis, and the citric acid cycle.
Toresson, Linda, Spillmann, Thomas, Hanisch, Franziska   +2 more
core   +1 more source

Kidney-Limited Microangiopathy Associated with Methionine Synthase (Cobalamin G) Deficiency in a Pediatric Patient: Case Report and Review of the Literature

Glomerular Diseases
Thrombotic microangiopathy (TMA) is a recognized sequela of inborn errors of metabolism impacting vitamin B12 (cobalamin) synthesis. Methylmalonic aciduria and homocystinuria, cobalamin deficiency type C is a well-known etiology for TMA.
Jonathan E. Zuckerman, Rachana Srivastava   +1 more
doaj   +1 more source

Reliable and powerful laboratory markers of cobalamin deficiency in the newborn: plasma and urinary methylmalonic acid

, 2016
Background: Diagnosing cobalamin deficiency is critical, given the high prevalence of cobalamin deficiency particularly in developing countries. Measuring serum cobalamin levels is of limited diagnostic sensitivity, in other words its specificity and ...
Kirecci, Ahmet, İŞLEK, Ali, KALAY, Salih, Kalay, Zuhal, KOKLU, Esad, PARLAK, Mesut, GUNEY, Ozgur   +6 more
core   +1 more source

Clinical diagnosis, treatment, and genetic analysis of adolescent onset holocarboxylase synthetase deficiency and cobalamin C deficiency: A case report and literature review

Metabolism Open
Background: Holocarboxylase Synthetase Deficiency (HCSD) is an uncommon autosomal recessive genetic disorder that manifests with symptoms such as metabolic acidosis, lethargy, hypotonia, seizures, and persistent rashes, typically emerging during infancy.
Ye Ren, Hongxing Dang, Yueqiang Fu, Chengjun Liu, Jing Li, Jinhua Cai   +5 more
doaj   +1 more source

The regulatory roles of liver and kidney in cobalamin (vitamin-B(12)) metabolism in the rat: the uptake and intracellular binding of cobalamin and the activity of the cobalamin-dependent enzymes in response to varying cobalamin supply

, 1984
To examine possible regulatory roles of liver and kidney in cobalamin metabolism, specific activities of the two cobalamin-dependent enzymes, uptake in vivo of cyano [57Co]cobalamin [( 57Co]CNCbl) and the binding of [57Co]Cbl to intracellular proteins ...
Treston, A.M., Cooksley, W.G.E., Bowman, E.P.W., Owens, J.A., Scott, J.S.D.   +4 more
core   +1 more source

Desensitization for Vitamin B12 Hypersensitivity and How to Do It

Biomedicines
Vitamin B12 is the common name for a group of cobalamins, which are cobalt corrines. Cobalamins are water-soluble B vitamins. Vitamin B12, as a coenzyme of various enzymes, is an essential component of many key metabolic processes in the body.
Kinga Lis
doaj   +1 more source

Therapeutic trial of cobalamin in patients with normal serum cobalamin levels and predicted cobalamin deficiency [PDF]

, 2003
Diagnosis of cobalamin deficiency can be difficult due to the variation in clinical presentation and lack of specificity of the laboratory findings. Although hypersegmentation and macrocytosis are important findings observed in cobalamin deficiency they ...
Ratip, Siret, Adigüzel, Cafer, Ovali, Ercüment, Ukinç, Kubilay, Kandemir, Nurten, ÖREM, ASIM, Karti, S. Sami, Bayik, Mahmut, Dane, Faysal, YILMAZ, MUSTAFA   +9 more
core   +1 more source

Cobalamin deficiency in children: A literature review

, 2013
Objective: The aim of this review is to present cobalamin deficiency in children with a specific focus on infants. Background: Cobalamin deficiency is caused by inadequate intake, malabsorption or inborn errors of vitamin B12 metabolism.
Moen, Synne Helland
core  

Cobalamin and Folic Acid Status in Relation to the Etiopathogenesis of Pancytopenia in Adults at a Tertiary Care Centre in North India

Anemia, 2012
Background. Pancytopenia has multiple etiologies like megaloblastic anemia, aplastic anemia, leukemia, and various infections. We investigated the clinical, etiological and hematological profile including bone marrow morphology of patients with ...
M. Premkumar, N. Gupta, T. Singh, T. Velpandian   +3 more
doaj   +1 more source

Hematological manifestations of autoimmune gastritis

Российский журнал гастроэнтерологии, гепатологии, колопроктологии, 2016
Aim of investigation. To estimate hematological disorders in patients with high titer of anti-parietal cell antibodies (APCA). Material and methods. Overall 71 patient with high serum APCA titer were included in original study.
Ye. A. Losik, V. T. Ivashkin
doaj   +1 more source