Results 71 to 80 of about 435,892 (214)

Exposure to Structurally Related Organophosphate Esters Elicits Distinct Metabolomic Perturbations in Daphnia magna

open access: yesEnvironmental Toxicology, EarlyView.
ABSTRACT Organophosphate esters (OPEs) are found ubiquitously in the environment and exposure to these chemicals has induced behavioral, developmental, and morphological impairments in several model organisms. Yet there is still a lack of understanding of how sub‐lethal exposure disrupts organism function at the molecular‐level, especially for Daphnia ...
Salwa Hajir   +4 more
wiley   +1 more source

Seasonal Dynamics of Community and Function of Gut Microbiome in Taihangshan Macaque (Macaca mulatta tcheliensis): Inferred From Metagenomic Data

open access: yesIntegrative Zoology, EarlyView.
A total of 435 non‐redundant metagenome‐assembled genomes (MAGs) were obtained from fecal samples of Taihangshan macaque across all four seasons. The alpha diversity of the gut microbiome in spring and winter was significantly higher than in summer and autumn. Furthermore, marked differences were detected in functional pathways and carbohydrate enzymes
Yanyan Zhou   +6 more
wiley   +1 more source

Dystrophia Smolandiensis is characterized by a novel NQO1 variant and a distinct phenotype from COL17A1‐associated epithelial recurrent erosion dystrophy

open access: yesActa Ophthalmologica, EarlyView.
Abstract Purpose To determine the molecular cause of the two epithelial recurrent erosion dystrophies, Dystrophia Smolandiensis and Dystrophia Helsinglandica, and to identify phenotypic differences between the two conditions. Methods DNA samples and clinical data from structured interview records were obtained from the Swedish families in which ...
Karl De Geer   +5 more
wiley   +1 more source

Spinal MRI supporting myelopathic origin of early symptoms in unsuspected cobalamin deficiency

open access: yes, 2003
We report two patients with subjectively progressive sensory symptoms and gait disturbance due to cobalamin deficiency, but only slight or absent abnormalities on neurological examination.
Fritschi, Jürg, Sturzenegger, Matthias
core   +1 more source

Co‐Culture of Mammalian Cells and Photosynthetic Microorganisms for Oxygen Supply in Engineered Tissues

open access: yesCell Proliferation, EarlyView.
Continuous 28‐day light exposure alters behaviours of articular cartilage progenitor cells (ACPCs) and mesenchymal stromal cells (MSCs). Co‐culture with Leptolyngbya and Synechococcus does not adversely affect the chondrogenic capacity of ACPCs over a 28‐day period, in contrast to co‐culture with Chlorella.
Meng Wang   +10 more
wiley   +1 more source

Prurigo Pigmentosa – an increasingly diagnosed dermatological condition associated with ketogenic diet

open access: yesJDDG: Journal der Deutschen Dermatologischen Gesellschaft, EarlyView.
SUMMARY Prurigo pigmentosa (PP) is a rare inflammatory dermatosis, clinically characterized by intensely pruritic, erythematous papules and papulovesicles, with reticular hyperpigmentation upon healing. We herein report four cases in adults of different ethnic backgrounds, in which the disease was associated with ketogenic metabolic states due to ...
Antigona Aliu   +7 more
wiley   +1 more source

Informing disinvestment with limited evidence: Cobalamin deficiency in the fatigued

open access: yes, 2015
OBJECTIVES: Health technology reassessment and disinvestment can be difficult due to uncertainties regarding available evidence. Pathology testing to investigate cobalamin (vitamin B12) deficiency is a strong case in point.
Jonathan Karnon (296040)   +6 more
core   +2 more sources

Body Composition Remodelling During GLP‐1‐Based Therapy: A Systematic Review and Meta‐Analysis Using a Hierarchical Physiological Framework

open access: yesDiabetes, Obesity and Metabolism, EarlyView.
ABSTRACT Background Body composition changes during glucagon‐like peptide‐1 (GLP‐1)‐based therapy remain incompletely characterized, particularly regarding their effects on adiposity, muscle quantity, and muscle quality. We conducted a systematic review and meta‐analysis using a predefined physiological framework to evaluate body composition ...
Maria Luizza Lopes Menezes   +6 more
wiley   +1 more source

Bridging gaps in diabetic neuropathy care: A Delphi‐based regional consensus from the Gulf Cooperation Council

open access: yesJournal of Diabetes Investigation, EarlyView.
A three‐round Delphi consensus developed GCC‐specific, evidence‐based recommendations for diabetic peripheral neuropathy (DPN) and painful diabetic neuropathy (PND). The consensus emphasizes proactive screening, early multimodal management, and addressing regional barriers to improve early detection, optimize management, and enhance quality of life ...
Abdulrahman Alshaikh   +13 more
wiley   +1 more source

Cobalamin and Folic Acid Status in Relation to the Etiopathogenesis of Pancytopenia in Adults at a Tertiary Care Centre in North India

open access: yesAnemia, 2012
Background. Pancytopenia has multiple etiologies like megaloblastic anemia, aplastic anemia, leukemia, and various infections. We investigated the clinical, etiological and hematological profile including bone marrow morphology of patients with ...
M. Premkumar   +3 more
doaj   +1 more source

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