Results 1 to 10 of about 973 (108)

Review of cobalamin status and disorders of cobalamin metabolism in dogs [PDF]

open access: yesJournal of Veterinary Internal Medicine, 2020
Disorders of cobalamin (vitamin B12) metabolism are increasingly recognized in small animal medicine and have a variety of causes ranging from chronic gastrointestinal disease to hereditary defects in cobalamin metabolism.
Stefanie Kather   +2 more
exaly   +6 more sources

The Neurology of Cobalamin [PDF]

open access: yesCanadian Journal of Neurological Sciences / Journal Canadien des Sciences Neurologiques, 1992
ABSTRACT:The following review indicates that the impact of cobalamin on neurologic disease extends far beyond the traditional myelopathy of classical pernicious anemia. The delineation of a broad spectrum of inherited disorders of cobalamin processing has served to illustrate and precisely define each step in the normal absorption, transport and ...
M I, Shevell, D S, Rosenblatt
openaire   +2 more sources

Interspecies transfer of biosynthetic cobalamin for complete dechlorination of trichloroethene by Dehalococcoides mccartyi

open access: yesWater Science and Technology, 2022
Complete dechlorination of trichloroethene (TCE) by Dehalococcoides mccartyi is catalyzed by reductive dehalogenases (RDases), which possess cobalamin as the crucial cofactor. However, virtually all D. mccartyi isolated thus far are corrinoid auxotrophs.
Haijun Li   +4 more
doaj   +1 more source

Enhanced cobalamin biosynthesis in Ensifer adhaerens by regulation of key genes with gradient promoters

open access: yesSynthetic and Systems Biotechnology, 2022
Cobalamin is an essential human vitamin widely used in the pharmaceutical, food, and feed additive industries and currently produced by bacteria or archaea. Ensifer adhaerens HY-1 is an industrial strain that also produces cobalamin.
Sha Xu   +5 more
doaj   +1 more source

Cobalamin related parameters and disease patterns in patients with increased serum cobalamin levels. [PDF]

open access: yesPLoS ONE, 2012
BACKGROUND:Measurement of serum cobalamin levels is routinely used to diagnose cobalamin deficiency. Surprisingly, approximately 15% of patients have high cobalamin levels and no consensus exists regarding the clinical implications.
Johan F B Arendt, Ebba Nexo
doaj   +1 more source

Cobalamins and cobalamin-dependent enzymes in Candida utilis [PDF]

open access: yesJournal of Bacteriology, 1979
Candida utilis has been shown to contain 4.7 pmol of cobalamin per g of wet cell paste. Purification of the cobalamin showed it to be a mixture of methylcobalamin and adenosylcobalamin. Two cobalamin-dependent enzyme systems have been found in the yeast: methylcobalamin-dependent methionine biosynthesis and leucine 2,3-aminomutase.
J M, Poston, B A, Hemmings
openaire   +2 more sources

The Intestinal Microbiome in Dogs with Chronic Enteropathies and Cobalamin Deficiency or Normocobalaminemia—A Comparative Study

open access: yesAnimals, 2023
Cobalamin deficiency is a common sequela of chronic enteropathies (CE) in dogs. Studies comparing the intestinal microbiome of CE dogs with cobalamin deficiency to those that are normocobalaminemic are lacking.
Linda Toresson   +6 more
doaj   +1 more source

The cobalamin-binding protein in zebrafish is an intermediate between the three cobalamin-binding proteins in human.

open access: yesPLoS ONE, 2012
In humans, three soluble extracellular cobalamin-binding proteins; transcobalamin (TC), intrinsic factor (IF), and haptocorrin (HC), are involved in the uptake and transport of cobalamin.
Eva Greibe, Sergey Fedosov, Ebba Nexo
doaj   +1 more source

In Dogs With Chronic Enteropathies, Can Oral B12 Tablets Be Used to Treat Hypocobalaminaemia?

open access: yesVeterinary Evidence, 2019
PICO question In dogs with chronic enteropathy does treatment with oral cobalamin compared to parenteral cobalamin provide serum cobalamin levels greater than 270 ng/L?
Avril McGinn
doaj   +1 more source

Cobalamin Scarcity Modifies Carbon Allocation and Impairs DMSP Production Through Methionine Metabolism in the Haptophyte Microalgae Tisochrysis lutea

open access: yesFrontiers in Marine Science, 2020
Cobalamin (vitamin B12) is a cobalt-containing enzymatic cofactor involved in methionine synthesis. Provided only by select bacteria and archaea in marine systems, this vitamin is known to limit primary production in different oceanic areas ...
Charlotte Nef   +8 more
doaj   +1 more source

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