Results 11 to 20 of about 26,570 (248)

Review of cobalamin status and disorders of cobalamin metabolism in dogs [PDF]

open access: yesJournal of Veterinary Internal Medicine, 2020
Disorders of cobalamin (vitamin B12) metabolism are increasingly recognized in small animal medicine and have a variety of causes ranging from chronic gastrointestinal disease to hereditary defects in cobalamin metabolism.
Stefanie Kather   +2 more
exaly   +8 more sources

Cobalamin related parameters and disease patterns in patients with increased serum cobalamin levels. [PDF]

open access: yesPLoS ONE, 2012
BACKGROUND:Measurement of serum cobalamin levels is routinely used to diagnose cobalamin deficiency. Surprisingly, approximately 15% of patients have high cobalamin levels and no consensus exists regarding the clinical implications.
Johan F B Arendt, Ebba Nexo
doaj   +2 more sources

The retention of cobalamin by the liver in the cobalamin-deficient rat

open access: yesClinical Science, 1985
1. The effect of cobalamin deficiency on whole body cobalamin content and its turnover was examined in the rat. Quantitative and qualitative changes in hepatic cobalamin were also followed and the effect of deficiency on the turnover of this cobalamin was determined in the isolated perfused liver. 2.
Owens, J.A.   +2 more
core   +6 more sources

The cobalamin-binding protein in zebrafish is an intermediate between the three cobalamin-binding proteins in human.

open access: yesPLoS ONE, 2012
In humans, three soluble extracellular cobalamin-binding proteins; transcobalamin (TC), intrinsic factor (IF), and haptocorrin (HC), are involved in the uptake and transport of cobalamin.
Eva Greibe, Sergey Fedosov, Ebba Nexo
doaj   +2 more sources

Neuroprotective mechanisms of cobalamin in ischemic stroke insights from network pharmacology and molecular simulations [PDF]

open access: yesScientific Reports
This study aims to systematically investigate the multi-target mechanisms of cobalamin in the treatment of ischemic stroke using network pharmacology and molecular docking approaches.
Li Zhou   +6 more
doaj   +2 more sources

Relationship between cobalamin deficiency and delirium in elderly patients undergoing cardiac surgery

open access: yesNeuropsychiatric Disease and Treatment, 2015
Utkan Sevuk,1 Erkan Baysal,2 Nurettin Ay,3 Yakup Altas,2 Rojhat Altindag,2 Baris Yaylak,2 Vahhac Alp,3 Ertan Demirtas4 1Department of Cardiovascular Surgery, Diyarbakir Gazi Yasargil Education and Research Hospital, Diyarbakir, 2Department of Cardiology,
Sevuk U   +7 more
doaj   +1 more source

Associations Between Anorexia Nervosa Severity, Liver Dysfunction, and Cobalamin Serum Concentration [PDF]

open access: yesNeuropsychiatric Disease and Treatment
Masatoshi Miyauchi,1,2 Taku Furuno,2,3 Makoto Kawase,1,2 Kanon Shinokawa,2 Nobuhiko Noguchi,1,2 Saki Hattori,2 Akira Suda,1,2 Toshihiro Misumi,4 Takeshi Asami2 1Psychiatric Center, Yokohama City University Medical Center, Yokohama, Kanagawa, Japan ...
Miyauchi M   +8 more
doaj   +2 more sources

The Neurology of Cobalamin [PDF]

open access: yesCanadian Journal of Neurological Sciences / Journal Canadien des Sciences Neurologiques, 1992
ABSTRACT:The following review indicates that the impact of cobalamin on neurologic disease extends far beyond the traditional myelopathy of classical pernicious anemia. The delineation of a broad spectrum of inherited disorders of cobalamin processing has served to illustrate and precisely define each step in the normal absorption, transport and ...
M I, Shevell, D S, Rosenblatt
openaire   +2 more sources

Interspecies transfer of biosynthetic cobalamin for complete dechlorination of trichloroethene by Dehalococcoides mccartyi

open access: yesWater Science and Technology, 2022
Complete dechlorination of trichloroethene (TCE) by Dehalococcoides mccartyi is catalyzed by reductive dehalogenases (RDases), which possess cobalamin as the crucial cofactor. However, virtually all D. mccartyi isolated thus far are corrinoid auxotrophs.
Haijun Li   +4 more
doaj   +1 more source

Enhanced cobalamin biosynthesis in Ensifer adhaerens by regulation of key genes with gradient promoters

open access: yesSynthetic and Systems Biotechnology, 2022
Cobalamin is an essential human vitamin widely used in the pharmaceutical, food, and feed additive industries and currently produced by bacteria or archaea. Ensifer adhaerens HY-1 is an industrial strain that also produces cobalamin.
Sha Xu   +5 more
doaj   +1 more source

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