Results 11 to 20 of about 22,754 (198)

Review of cobalamin status and disorders of cobalamin metabolism in dogs [PDF]

Journal of Veterinary Internal Medicine, 2020
Disorders of cobalamin (vitamin B12) metabolism are increasingly recognized in small animal medicine and have a variety of causes ranging from chronic gastrointestinal disease to hereditary defects in cobalamin metabolism.
Stefanie Kather, Franziska Dengler, Peter Kook   +2 more
exaly   +6 more sources

Neuroprotective mechanisms of cobalamin in ischemic stroke insights from network pharmacology and molecular simulations [PDF]

Scientific Reports
This study aims to systematically investigate the multi-target mechanisms of cobalamin in the treatment of ischemic stroke using network pharmacology and molecular docking approaches.
Li Zhou, Yanli Cai, Haiyun Wu, Jiani Wang, Fangmei Xiao, Pingping Liu, Qin Yang   +6 more
doaj   +2 more sources

Associations Between Anorexia Nervosa Severity, Liver Dysfunction, and Cobalamin Serum Concentration [PDF]

Neuropsychiatric Disease and Treatment
Masatoshi Miyauchi,1,2 Taku Furuno,2,3 Makoto Kawase,1,2 Kanon Shinokawa,2 Nobuhiko Noguchi,1,2 Saki Hattori,2 Akira Suda,1,2 Toshihiro Misumi,4 Takeshi Asami2 1Psychiatric Center, Yokohama City University Medical Center, Yokohama, Kanagawa, Japan ...
Miyauchi M, Furuno T, Kawase M, Shinokawa K, Noguchi N, Hattori S, Suda A, Misumi T, Asami T   +8 more
doaj   +2 more sources

The Neurology of Cobalamin [PDF]

Canadian Journal of Neurological Sciences / Journal Canadien des Sciences Neurologiques, 1992
ABSTRACT:The following review indicates that the impact of cobalamin on neurologic disease extends far beyond the traditional myelopathy of classical pernicious anemia. The delineation of a broad spectrum of inherited disorders of cobalamin processing has served to illustrate and precisely define each step in the normal absorption, transport and ...
M I, Shevell, D S, Rosenblatt
openaire   +2 more sources

Interspecies transfer of biosynthetic cobalamin for complete dechlorination of trichloroethene by Dehalococcoides mccartyi

Water Science and Technology, 2022
Complete dechlorination of trichloroethene (TCE) by Dehalococcoides mccartyi is catalyzed by reductive dehalogenases (RDases), which possess cobalamin as the crucial cofactor. However, virtually all D. mccartyi isolated thus far are corrinoid auxotrophs.
Haijun Li, Shanming Wei, Na Liu, Yalu Du, Guantao Ding   +4 more
doaj   +1 more source

Enhanced cobalamin biosynthesis in Ensifer adhaerens by regulation of key genes with gradient promoters

Synthetic and Systems Biotechnology, 2022
Cobalamin is an essential human vitamin widely used in the pharmaceutical, food, and feed additive industries and currently produced by bacteria or archaea. Ensifer adhaerens HY-1 is an industrial strain that also produces cobalamin.
Sha Xu, Zhiqiang Xiao, Shiqin Yu, Weizhu Zeng, Yongming Zhu, Jingwen Zhou   +5 more
doaj   +1 more source

Cobalamin related parameters and disease patterns in patients with increased serum cobalamin levels. [PDF]

PLoS ONE, 2012
BACKGROUND:Measurement of serum cobalamin levels is routinely used to diagnose cobalamin deficiency. Surprisingly, approximately 15% of patients have high cobalamin levels and no consensus exists regarding the clinical implications.
Johan F B Arendt, Ebba Nexo
doaj   +1 more source

Cobalamins and cobalamin-dependent enzymes in Candida utilis [PDF]

Journal of Bacteriology, 1979
Candida utilis has been shown to contain 4.7 pmol of cobalamin per g of wet cell paste. Purification of the cobalamin showed it to be a mixture of methylcobalamin and adenosylcobalamin. Two cobalamin-dependent enzyme systems have been found in the yeast: methylcobalamin-dependent methionine biosynthesis and leucine 2,3-aminomutase.
J M, Poston, B A, Hemmings
openaire   +2 more sources

The Intestinal Microbiome in Dogs with Chronic Enteropathies and Cobalamin Deficiency or Normocobalaminemia—A Comparative Study

Animals, 2023
Cobalamin deficiency is a common sequela of chronic enteropathies (CE) in dogs. Studies comparing the intestinal microbiome of CE dogs with cobalamin deficiency to those that are normocobalaminemic are lacking.
Linda Toresson, Jan S. Suchodolski, Thomas Spillmann, Bruna C. Lopes, Johnathan Shih, Jörg M. Steiner, Rachel Pilla   +6 more
doaj   +1 more source

The cobalamin-binding protein in zebrafish is an intermediate between the three cobalamin-binding proteins in human.

PLoS ONE, 2012
In humans, three soluble extracellular cobalamin-binding proteins; transcobalamin (TC), intrinsic factor (IF), and haptocorrin (HC), are involved in the uptake and transport of cobalamin.
Eva Greibe, Sergey Fedosov, Ebba Nexo
doaj   +1 more source