Results 21 to 30 of about 1,025 (157)

Decreased cobalamin sensitivity and biological aging acceleration in the general population

The Journal of Nutrition, Health and Aging
Background: The evidence on the association between cobalamin (Cbl) and aging or relevant outcomes is limited and controversial. We aimed to investigate the relationships between cobalamin intake- and function-related biomarkers and biological aging ...
Fan Tang, Hongbin Qiu, Yan Liu, Junchen Guo, Zheming Huang, Shaohong Fang, Yiying Zhang, Shanjie Wang   +7 more
doaj   +1 more source

Transcriptomic and proteomic changes associated with cobalamin-dependent propionate production by the rumen bacterium Xylanibacter ruminicola

mSystems
Xylanibacter ruminicola is an abundant rumen bacterium that produces propionate in a cobalamin (vitamin B12)-dependent manner via the succinate pathway.
Sam C. Mahoney-Kurpe, Nikola Palevich, Dragana Gagic, Patrick J. Biggs, Peter M. Reid, Ianina Altshuler, Phillip B. Pope, Graeme T. Attwood, Christina D. Moon   +8 more
doaj   +1 more source

Cobalamin and folate status in 6 to 35 months old children presenting with acute diarrhea in Bhaktapur, Nepal.

PLoS ONE, 2014
BackgroundCobalamin and folate are essential micronutrients and are important in DNA and RNA synthesis, cell proliferation, growth, hematopoiesis, and cognitive function.
Manjeswori Ulak, Ram K Chandyo, Ramesh K Adhikari, Pushpa R Sharma, Halvor Sommerfelt, Helga Refsum, Tor A Strand   +6 more
doaj   +1 more source

Dynamics and interactions of cobalamin and folate status during advanced aging – a longitudinal study in a community-dwelling cohort with multiple follow-ups

Nutrition Journal, 2020
Background Older people are reported to be prone to imbalances between cobalamin and folate status with possible adverse effects on health. This longitudinal study investigates dynamics and interactions of cobalamin and folate status in a cohort of ...
Alexandra Jungert, Carola Zenke-Philippi, Monika Neuhäuser-Berthold   +2 more
doaj   +1 more source

Prevalence of serum cobalamin and folate deficiency among children aged 6–59 months: A hospital-based cross-sectional study from Northern India

Journal of Family Medicine and Primary Care, 2022
Context: Cobalamin and folate are essential for the synthesis of nucleic acids and in the maintenance of myelin. They are required during the period of the rapid growth of infancy and childhood.
Surbhi Gupta, Partha Haldar, Archana Singh, Sumit Malhotra, Shashi Kant   +4 more
doaj   +1 more source

Fat digestibility is reduced in old cats with subnormal cobalamin concentrations

Journal of Nutritional Science, 2014
Fat digestibility is decreased in old cats for unknown reasons. Subclinical gastrointestinal diseases and pancreatic dysfunction, both related to ageing, can affect food digestibility.
Anna Salas, Carmen-Loreto Manuelian, Marta Garganté, Núria Sanchez, Sonia Fernández, Marco Compagnucci, Jose Joaquín Cerón, Isabelle Jeusette, Lluís Vilaseca, Celina Torre   +9 more
doaj   +1 more source

Genetic testing is necessary for correct diagnosis and treatment in patients with isolated methylmalonic aciduria: a case report

BMC Pediatrics, 2021
Background Isolated methylmalonic aciduria can be caused by pathogenic mutations in the gene for methylmalonyl-CoA mutase or in the genes encoding enzymes involved in the intracellular metabolism of cobalamin.
Katarína Brennerová, Martina Škopková, Mária Ostrožlíková, Jana Šaligová, Juraj Staník, Vladimír Bzdúch, Daniela Gašperíková   +6 more
doaj   +1 more source

Sudden anaerobization in Amphibacillus xylanus increases intracellular labile ferrous iron and inhibits cell growth

FEBS Open Bio, EarlyView.
Abruptly changing from aerobic to anaerobic conditions (sudden anaerobization) induced growth inhibition and a significant increase in intracellular labile ferrous iron in the aerotolerant anaerobe Amphibacillus xylanus. We found that free flavins mediate efficient electron transfer from NADH to ferric iron under anaerobic conditions, suggesting that ...
Shinya Kimata, Yoichi Sakai, Keisuke Tanaka, Etsuro Yoshimura, Ken Kitano, Morio Ishikawa, Tadahiro Nakamoto, Tsutomu Takayama, Hirofumi Inoue, Kaho Nomura, Tomonori Suzuki, Masataka Uchino, Akira Abe, Youichi Niimura   +13 more
wiley   +1 more source

Cobalamin deficiency resulting in a rare haematological disorder: a case report

Journal of Medical Case Reports, 2009
Introduction We present the case of a patient with a cobalamin deficiency resulting in pancytopaenia, emphasizing the importance to define, diagnose and treat cobalamin deficiency. Case presentation A 52-year-old man from the Democratic Republic of Congo
Chapuis Thomas M, Favrat Bernard, Bodenmann Patrick   +2 more
doaj   +1 more source

Prevalence of Dietary Supplement Use and Potential Medication Interactions Among Adults with Systemic Lupus Erythematosus

Arthritis Care &Research, Accepted Article.
Objective To characterize the prevalence and correlates of dietary supplement use, identify commonly used supplements, and evaluate potential supplement–medication interactions among adults with systemic lupus erythematosus (SLE). Methods We analyzed cross‐sectional data from 451 adults in the Approaches to Positive, Patient‐centered Experiences of ...
Sarah L. Patterson, Russell Ellyson, Jessica Fitzpatrick, Ghizlane Yaakoubi, Bradley Pearce, S. Sam Lim, Jinoos Yazdany, Laura C. Plantinga   +7 more
wiley   +1 more source