Results 31 to 40 of about 11,202 (214)

A dodecylamine derivative of cyanocobalamin potently inhibits the activities of cobalamin-dependent methylmalonyl-CoA mutase and methionine synthase of Caenorhabditis elegans

FEBS Open Bio, 2014
In this study, we showed that cyanocobalamin dodecylamine, a ribose 5′-carbamate derivative of cyanocobalamin, was absorbed and accumulated to significant levels by Caenorhabditis elegans and was not further metabolized.
Tomohiro Bito, Yukinori Yabuta, Tsuyoshi Ichiyanagi, Tsuyoshi Kawano, Fumio Watanabe   +4 more
doaj   +1 more source

Spinal MRI supporting myelopathic origin of early symptoms in unsuspected cobalamin deficiency [PDF]

, 2003
We report two patients with subjectively progressive sensory symptoms and gait disturbance due to cobalamin deficiency, but only slight or absent abnormalities on neurological examination.
Fritschi, Jürg, Sturzenegger, Matthias
core   +1 more source

Informing disinvestment with limited evidence: Cobalamin deficiency in the fatigued [PDF]

, 2015
OBJECTIVES: Health technology reassessment and disinvestment can be difficult due to uncertainties regarding available evidence. Pathology testing to investigate cobalamin (vitamin B12) deficiency is a strong case in point.
Jonathan Karnon (296040), Adam G. Elshaug (3344180), John R. Moss (2526133), George Mnatzaganian (447529), Janet Hiller (18924124), Oliver R. Frank (19000292), Michael Metz (19000289)   +6 more
core   +3 more sources

Hereditary intrinsic factor deficiency in China caused by a novel mutation in the intrinsic factor gene—a case report

BMC Medical Genetics, 2020
Background Hereditary intrinsic factor deficiency is a rare disease characterized by cobalamin deficiency with the lack of gastric intrinsic factor because of gastric intrinsic factor (GIF) mutations.
Jing Ruan, Bing Han, Junling Zhuang, Miao Chen, Fangfei Chen, Yuzhou Huang, Wenzhe Zhou   +6 more
doaj   +1 more source

Serum cobalamin and methylmalonic acid concentrations in juvenile dogs with parvoviral enteritis or other acute enteropathies

Journal of Veterinary Internal Medicine, 2023
Background Low serum cobalamin concentrations have been associated with ileal malabsorption in dogs with chronic enteropathy. Increased serum methylmalonic acid (MMA) concentrations indicate cobalamin deficiency on a cellular level.
Michael Hung, Justin Heinz, Jӧrg M. Steiner, Jan Suchodolski, Jonathan Lidbury   +4 more
doaj   +1 more source

Analysis of the causes of vitamin B12 deficiency in different age groups - a review of the literature

Journal of Education, Health and Sport, 2022
Introduction and purpose  Vitamin B12 plays an important role in the process of erythropoiesis and the proper functioning of the nervous system. Its source for humans is food, in particular meat, eggs and shellfish.
Adrianna Nieciecka, Kornelia Kędziora-Kornatowska, Magdalena Lamch, Monika Jabłońska, Natalia Błasik, Agata Wójcik   +5 more
doaj   +1 more source

Cobalamin deficiency in dogs and cats [PDF]

, 2018
Cobalamin is a member of the B-group of vitamins and a cofactor for metabolic processes like nucleic acid synthesis, amino acid synthesis, and the citric acid cycle.
Toresson, Linda, Spillmann, Thomas, Hanisch, Franziska   +2 more
core   +1 more source

An update on cobalamin deficiency in adults [PDF]

QJM, 2009
Cobalamin (vitamin B12) deficiency is particularly common in the elderly (>65 years of age), but is often unrecognized because of its subtle clinical manifestations; although they can be potentially serious, particularly from a neuropsychiatric and hematological perspective.
Dali-Youcef, N., Andres, E.
openaire   +3 more sources

An on-line solid phase extraction procedure for the routine quantification of urinary methylmalonic acid by liquid chromatography-tandem mass spectrometry [PDF]

, 2010
Background: The goal of this study was to develop and to validate an improved isotope-dilution-liquid chromatography-tandem mass spectrometry (LC-MS/MS) method for the quantification of methylmalonic acid (MMA) in urine.
Michael Vogeser, Lorenzl, Stephan, Stephan Lorenzl, Fabian Kirchhoff, Vogeser, Michael, Kirchhoff, Fabian   +5 more
core   +1 more source

Review: State of the knowledge on the importance of folates and cobalamin for dairy cow metabolism

Animal, 2023
Synthesis of B vitamins by the rumen microbiota is usually sufficient to avoid the appearance of clinical deficiency symptoms in dairy cows under normal feeding conditions.
C.L. Girard, M. Duplessis
doaj   +1 more source