Results 101 to 110 of about 11,202 (214)
Background: Autoimmune gastritis (AG) is a chronic gastritis characterized by inflammation of the stomach lining and is often associated with intrinsic factor deficiency and pernicious anemia.
Zainab Mohammed Jasim +2 more
doaj +1 more source
ABSTRACT Background Cognitive impairment is common in bipolar disorder (BD), but the underlying pathophysiology remains unclear. This systematic review aimed to (1) summarize all literature describing relationships of biofluid biomarkers and cognition in BD and (2) identify which biofluid biomarkers correlate most consistently with cognition in BD ...
Alexandra J. M. Beunders +21 more
wiley +1 more source
The regulatory roles of liver and kidney in cobalamin (vitamin-B(12)) metabolism in the rat: the uptake and intracellular binding of cobalamin and the activity of the cobalamin-dependent enzymes in response to varying cobalamin supply [PDF]
To examine possible regulatory roles of liver and kidney in cobalamin metabolism, specific activities of the two cobalamin-dependent enzymes, uptake in vivo of cyano [57Co]cobalamin [( 57Co]CNCbl) and the binding of [57Co]Cbl to intracellular proteins ...
Treston, A.M. +4 more
core +1 more source
Background: The gold standard for cobalamin deficiency treatment is administration of cobalamin by intramuscular injection. The injection is painful and inconvenient, particularly for elderly persons.
Monique P.H. Tillemans, PharmD +4 more
doaj +1 more source
The metabolism of ribose starts with the phosphorylation of its 5′ hydroxyl group. Salmonella typhimurium has two kinases that perform this function, namely ribose rinase (RbsK) and deoxyribose kinase (DeoK). Here we report a new ribose kinase that we named RikA. The illustration was partially created in BioRender.
Regan D. McCormick +2 more
wiley +1 more source
Phenotype, treatment practice and outcome in the cobalamin-dependent remethylation disorders and MTHFR deficiency: Data from the E-HOD registry [PDF]
Aim: To explore the clinical presentation, course, treatment and impact of early treatment in patients with remethylation disorders from the European Network and Registry for Homocystinurias and Methylation Defects (E-HOD) international web-based ...
Ballhausen, Diana +136 more
core +1 more source
Neurocognitive and Psychologic Bio-Markers in Old People in Mashhad, Iran
Background and Objectives: Incidence of neurocognitive and psychologic disorders in elderly seems to become high There are numerous factors affecting neurocognitive functions like vascular factors, Vitamin B12 and folate and homocysteine levels.
L Manavifar +5 more
doaj
Here, we demonstrate that polysaccharide chain length regulation plays a distinct role in enabling formation of a cyclic molecule important for the bacterial cell surface. However, this function is necessary, but not sufficient for the cyclic molecule's biosynthesis.
Joseph F. Carr +4 more
wiley +1 more source
S‐Adenosyl‐d‐Methionine as a Non‐Physiological Substrate for a Wide Range of SAM‐Dependent Enzymes
From methylation and cyclisation to radical chemistry, diverse enzyme classes utilise the non‐canonical cofactor d‐SAM. These findings reveal an unexpected tolerance of SAM‐dependent catalysis towards inversion of the methionine Cα stereocentre. The ability of SAM‐dependent enzymes to accept S‐adenosyl‐d‐methionine [d‐SAM, (SS,RCα)‐SAM] instead of the ...
Philipp Germer +17 more
wiley +1 more source
Idiopathic recurrent pyoderma gangrenosum with cobalamin deficiency in a 62-year-old male: a case report. [PDF]
Sitaula S +4 more
europepmc +1 more source

