Results 191 to 200 of about 43,635 (227)

Positron emission tomography in primary brain tumours using cobalt-55

Nuclear Medicine Communications, 1997
Primary brain tumours are usually assessed by computed tomography (CT) and magnetic resonance imaging (MRI), sometimes in conjunction with positron emission tomography (PET). We used cobalt-55 (55Co) as a calcium (Ca) tracer to visualize decaying tumour tissue, based on the fact that Ca-influx is essential in both cell death and leukocyte activation ...
Jansen, HM, Dierckx, RA, Hew, JM, Paans, AM, Minderhoud, JM, Korf, J   +5 more
  +10 more sources

Cobalt-55 positron emission tomography in ischemic stroke

Clinical Neurology and Neurosurgery, 1997
After acute cerebral stroke, the (peri-) infarct tissue is characterized by calcium (Ca)-mediated neuronal damage and inflammatory processes. Monitoring Ca-mediated damage using the isotope cobalt-55 (Co) as a Ca-tracer may enable PET-imaging of this tissue.
Jansen, HML, Paans, AMJ, Vliet, AMV, VeenmavanderDuin, L, BolwijnMeijer, CJW, Pruim, J, Willemsen, ATM, Franssen, EJF, Minderhoud, JM, Korf, J   +9 more
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Cobalt-55 positron emission tomography in recurrent ischaemic stroke

Clinical Neurology and Neurosurgery, 1999
The present study investigates if Cobalt-55 (55Co) positron emission tomography (PET) allows us to distinguish and detect recent, recurrent strokes in patients who had already suffered a previous infarct in the same vascular territory. Fourteen patients with recurrent strokes underwent a 55Co PET scan of the brain. Recently infarcted areas, less than 2
De Reuck, J, Santens, P, Keppens, J, De Bleecker, J, Strijckmans, K, Goethals, P, Lemahieu, I, Korf, J   +7 more
openaire   +2 more sources

Cobalt-55 positron emission tomography in relapsing-progressive multiple sclerosis

Journal of the Neurological Sciences, 1995
Multiple sclerosis (MS) is an immune-mediated disease of the white matter in the brain that can have a progressive course. However, the progression of relapsing-remitting (RR) MS into relapsing-progressive (RP) MS might represent a more fundamental change in disease activity, i.e. decay of vulnerable neurons and oligodendrocytes.
JANSEN, HML, WILLEMSEN, ATM, SINNIGE, LGF, PAANS, AMJ, HEW, JM, FRANSSEN, EJF, ZORGDRAGER, AM, PRUIM, J, MINDERHOUD, JM, KORF, J   +9 more
openaire   +3 more sources

The significance of cobalt-55 positron emission tomography in ischemic stroke

Journal of Stroke and Cerebrovascular Diseases, 1999
Cobalt-55 ((55)Co) has been shown to be an interesting positron emission tomography (PET) tracer that may reflect calcium (Ca) influx in damaged cerebral tissue. Because Ca load is important in the ischemic cascade, the exact meaning of (55)Co PET in stroke patients has to be shown.
J, De Reuck, H, Stevens, H, Jansen, J, Keppens, K, Strijckmans, P, Goethals, I, Lemahieu, P, Santens, J, Korf   +8 more
openaire   +2 more sources

Production of cobalt-55, a short-lived, positron emitting radiolabel for bleomycin

International Journal of Radiation Applications and Instrumentation. Part A. Applied Radiation and Isotopes, 1986
The production and radiochemical separation of 55Co from deuteron irradiation of enriched 54Fe target is described. Methods used for the recovery and reuse of the target material (54Fe) are also described. The yield of 55Co at 12 MeV incident deuteron energy is 1.7 mCi per mu Ah at end of bombardment and the contamination with 57Co is 0.016%.
Sharma, HL, Zweit, J, Smith, A, Downey, S   +3 more
openaire   +3 more sources

A PSMA Ligand Labeled with Cobalt-55 for PET Imaging of Prostate Cancer

Molecular Imaging and Biology, 2017
Prostate-specific membrane antigen (PSMA) comprises a recognized target for molecular imaging of prostate cancer. As such, radiolabeled PSMA inhibitors are of great value for diagnosis and staging of this disease. Herein, we disclose the preclinical characterization of [55Co]PSMA-617 for positron emission tomography (PET)/x-ray computed tomography (CT)
Dam, Johan Hygum, Olsen, Birgitte Brinkmann, Baun, Christina, Høilund-Carlsen, Poul Flemming, Thisgaard, Helge   +4 more
openaire   +3 more sources

Cobalt-55 positron emission tomography in symptomatic atherosclerotic carotid artery disease: borderzone versus territorial infarcts

Clinical Neurology and Neurosurgery, 2004
Borderzone as well as territorial infarcts can occur in severe atherosclerotic carotid artery disease. It remains controversial whether the borderzone distribution of infarcts is due to hypoperfusion or due to artery-to-artery embolism.The present study investigates whether cobalt-55 (55Co) positron emission tomography (PET) shows a different pattern ...
Jacques, De Reuck, Koen, Paemeleire, Patrick, Santens, Karel, Strijckmans, Ignace, Lemahieu   +4 more
openaire   +2 more sources

Cobalt-55 Positron Emission Tomography of Ipsilateral Thalamic and Crossed Cerebellar Hypometabolism after Supratentorial Ischaemic Stroke

Cerebrovascular Diseases, 1999
Cobalt-55 (⁵⁵Co) is a positron emission tomography (PET) tracer used to demonstrate brain damage, possibly associated to calcium-mediated processes. The degree of ⁵⁵Co accumulation correlates with the severity of ischaemia in stroke patients.
De Reuck, J, Stevens, H, Jansen, H, Keppens, J, Strijckmans, K, Goethals, P, Lemahieu, I, Santens, P, Korf, J   +8 more
openaire   +3 more sources

Cyclotron production of carrier-free cobalt-55, a new positron-emitting label for bleomycin

The International Journal of Applied Radiation and Isotopes, 1979
A method for producing carrier-free 55Co (18.5 h) by proton bombardment of natural iron targets is presented. 55Co is formed primarily by means of the 56Fe (p, 2n)55Co reaction. Thin-target and thick-target yields as well as cross-section calculations are given in the 15-MeV to 40-MeV proton-energy range. Half-life measurements indicate a value of 18.5
M.C. Lagunas-Solar, J.A. Jungerman
openaire   +1 more source