Results 11 to 20 of about 13,397 (223)

COBRA methods and metabolic drug targets in cancer [PDF]

Molecular & Cellular Oncology, 2018
The identification of therapeutic strategies exploiting the metabolic alterations of malignant cells is a relevant area in cancer research. Here, we discuss a novel computational method, based on the COBRA (COnstraint-Based Reconstruction and Analysis ...
Iñigo Apaolaza, Edurne San José-Eneriz, Xabier Agirre, Felipe Prósper, Francisco J. Planes   +4 more
doaj   +5 more sources

Financial Performance Analysis Using the Merec-Based Cobra Method: An Application to Traditional and Low-Cost Airlines

Gospodarka Narodowa. The Polish Journal of Economics
The aim of this study is to examine the impact of the COVID-19 pandemic on the financial performance of traditional and low-cost airlines. In this context, the financial performance of 32 traditional and 14 low-cost airlines operating in different ...
Veysi Asker
doaj   +4 more sources

COBRA-IV: the model and the method [PDF]

, 1977
The objective of this report is to present the mathematical basis of the COBRA-IV computer program (Wheeler et al., 1976) being developed by Battelle, Pacific Northwest Laboratory.
Stewart, C.W., Wheeler, C.L., McMonagle, C.A., Cuta, J.M., Trent, D.S., Cena, R.J.   +5 more
core   +3 more sources

COBRA: A Fast and Simple Method for Active Clustering with Pairwise Constraints [PDF]

Proceedings of the Twenty-Sixth International Joint Conference on Artificial Intelligence, 2017
Clustering is inherently ill-posed: there often exist multiple valid clusterings of a single dataset, and without any additional information a clustering system has no way of knowing which clustering it should produce.
Blockeel, Hendrik, Hendrik Blockeel, Dumancic, Sebastijan, Sebastijan Dumancic, Toon Van Craenendonck, Van Craenendonck, Toon   +5 more
core   +3 more sources

Multi-COBRA hemagglutinin formulated with cGAMP microparticles elicits protective immune responses against influenza viruses

mSphere
In humans, seasonal influenza viruses cause epidemics. Avian influenza viruses are of particular concern because they can infect multiple species and lead to unpredictable and severe disease.
Xiaojian Zhang, Hua Shi, Dylan A. Hendy, Eric M. Bachelder, Kristy M. Ainslie, Ted M. Ross   +5 more
doaj   +4 more sources

Purification and antibacterial activities of an L-amino acid oxidase from king cobra (Ophiophagus hannah) venom [PDF]

Journal of Venomous Animals and Toxins including Tropical Diseases, 2012
Some constituents of snake venom have been found to display a variety of biological activities. The antibacterial property of snake venom, in particular, has gathered increasing scientific interest due to antibiotic resistance. In the present study, king
CS Phua, J Vejayan, S Ambu, G Ponnudurai, A Gorajana   +4 more
doaj   +2 more sources

COBRA: A Hybrid Method for Software Cost Estimation, Benchmarking, and Risk Assessment

Proceedings of the 20th International Conference on Software Engineering, 1997
Current cost estimation techniques have a number of drawbacks. For example, developing algorithmic models requires extensive past project data. Also, off-the-shelf models have been found to be difficult to calibrate but inaccurate without calibration ...
Khaled El Emam, K. El Emam, Frank Bomarius, L.C. Briand, Lionel C. Briand, F. Bomarius, Lionel C. Bri   +6 more
core   +2 more sources

ENT COBRA (Consortium for Brachytherapy Data Analysis): interdisciplinary standardized data collection system for head and neck patients treated with interventional radiotherapy (brachytherapy)

Journal of Contemporary Brachytherapy, 2016
Purpose : Aim of the COBRA (Consortium for Brachytherapy Data Analysis) project is to create a multicenter group (consortium) and a web-based system for standardized data collection. Material and methods: GEC-ESTRO (Groupe Européen de Curiethérapie –
Luca Tagliaferri, György Kovács, Rosa Autorino, Ashwini Budrukkar, Jose Luis Guinot, Guido Hildebrand, Bengt Johansson, Rafael Martìnez Monge, Jens E. Meyer, Peter Niehoff, Angeles Rovirosa, Zoltàn Takàcsi-Nagy, Nicola Dinapoli, Vito Lanzotti, Andrea Damiani, Tamer Soror, Vincenzo Valentini   +16 more
doaj   +2 more sources

Results of the ribonuclease isolation from the cobra venom by ion-exchange column with CM-cellulose method [PDF]

TAP CHI SINH HOC, 2014
In this paper, the cobra (Naja atra Cantor, 1842) venom ribonuclease (RNase) was isolated of ion-exchange column with CM-cellulose method. The chromatographic isolation was carried out at different values of pH within an interval of pH = 4.4 – 5.8. At pH
Giang Thai Son, Thiet, Nguyen Van, Nguyen Van Thiet, Son, Giang Thai   +3 more
core   +2 more sources

Analysis of the circular economy of Serbia based on the Cobra method

Journal of Economics
Recently, the problem of the circular economy has been very topical. In the literature, it is investigated from different angles. This study analyzes the problem of the circular economy in Serbia based on the COBRA method. The results of the COBRA method
Lukic, Radojko
core   +2 more sources