Results 11 to 20 of about 12,151 (195)

COBRA methods and metabolic drug targets in cancer [PDF]

Molecular & Cellular Oncology, 2018
The identification of therapeutic strategies exploiting the metabolic alterations of malignant cells is a relevant area in cancer research. Here, we discuss a novel computational method, based on the COBRA (COnstraint-Based Reconstruction and Analysis ...
Iñigo Apaolaza, Edurne San José-Eneriz, Xabier Agirre, Felipe Prósper, Francisco J. Planes   +4 more
doaj   +4 more sources

The Effect of the Cobra Stretch Training Method on Students' Kayang Abilities

Gladi: Jurnal Ilmu Keolahragaan
The bridge (kayang) is a fundamental floor gymnastics skill that requires spinal flexibility, back muscle strength, and abdominal muscle strength.
Yoga Aziz Kurnia Anggara, Nurman Ramadhan, Mohamad Da'i   +2 more
doaj   +2 more sources

Financial Performance Analysis Using the Merec-Based Cobra Method: An Application to Traditional and Low-Cost Airlines

Gospodarka Narodowa. The Polish Journal of Economics
The aim of this study is to examine the impact of the COVID-19 pandemic on the financial performance of traditional and low-cost airlines. In this context, the financial performance of 32 traditional and 14 low-cost airlines operating in different ...
Veysi Asker
doaj   +3 more sources

Examination of Financial Performance of Manufacturing Sector Companies in the BIST Participation Sustainability Index by MEREC and COBRA Methods

Ekonomi, Politika & Finans Araştırmaları Dergisi
Measuring the financial performance of companies is important in terms of ensuring superiority in competition, achieving profitability targets, and ensuring the continuity of activities.
Kemal Vatansever, Tuba Bayraktar
doaj   +4 more sources

Financial performance evaluation of firms in BIST 100 index with ITARA and COBRA methods

Financial Innovation
Evaluating firms’ financial performance is important for survival in the competitive environment arising from technological advancements and gaining a competitive advantage.
Ali Katrancı, Nilsen Kundakcı, Dragan Pamucar   +2 more
doaj   +4 more sources

Diagnosis of Indian Big Four and monocled Cobra snakebites in envenomed plasma using smartphone-based digital imaging colourimetry method.

PLoS Neglected Tropical Diseases
BackgroundVenomous or dry bites can result from snake envenomation. Therefore, developing a detection test for venomous snakebites in envenomed patients can prevent from unnecessary antivenom therapy for dry bites, thereby, saving them from adverse ...
Upasana Puzari, Mojibur R Khan, Ashis K Mukherjee   +2 more
doaj   +3 more sources

COBRA: A Fast and Simple Method for Active Clustering with Pairwise Constraints [PDF]

Proceedings of the Twenty-Sixth International Joint Conference on Artificial Intelligence, 2017
Clustering is inherently ill-posed: there often exist multiple valid clusterings of a single dataset, and without any additional information a clustering system has no way of knowing which clustering it should produce. This motivates the use of constraints in clustering, as they allow users to communicate their interests to the clustering system ...
Van Craenendonck, Toon, Dumancic, Sebastijan, Blockeel, Hendrik   +2 more
openaire   +2 more sources

The ‘COmorBidity in Relation to AIDS’ (COBRA) cohort: Design, methods and participant characteristics [PDF]

PLOS ONE, 2018
Persons living with HIV on combination antiretroviral therapy (cART) may be at increased risk of the development of age-associated non-communicable comorbidities (AANCC) at relatively young age. It has therefore been hypothesised that such individuals, despite effective cART, may be prone to accelerated aging.The COmorBidity in Relation to AIDS (COBRA)
Davide De Francesco, Ferdinand W Wit, James H Cole, Neeltje A Kootstra, Alan Winston, Caroline A Sabin, Jonathan Underwood, Rosan A van Zoest, Judith Schouten, Katherine W Kooij, Maria Prins, Giovanni Guaraldi, Matthan W A Caan, David Burger, Claudio Franceschi, Claude Libert, Alexander Bürkle, Peter Reiss, COmorBidity in Relation to AIDS (COBRA) collaboration   +18 more
openaire   +10 more sources

COBRA-IV: the model and the method [PDF]

, 1977
The objective of this report is to present the mathematical basis of the COBRA-IV computer program (Wheeler et al., 1976) being developed by Battelle, Pacific Northwest Laboratory. The COBRA-IV code is an extended version of the COBRA-IIIC subchannel analysis code that computes the flow and enthalpy distributions in nuclear fuel rod bundles and cores ...
Stewart, C.W., Wheeler, C.L., Cena, R.J., McMonagle, C.A., Cuta, J.M., Trent, D.S.   +5 more
openaire   +2 more sources

Buprenorphine and methadone in the treatment of opioid dependence: methods and design of the COBRA study [PDF]

International Journal of Methods in Psychiatric Research, 2005
Buprenorphine and methadone are the two established substitution drugs licensed in many countries for the treatment of opioid dependence. Little is known, however, about how these two drugs are applied and how they work in clinical practice. In this paper we present the aims, methods, design and sampling issues of a collaborative multi-stage ...
Hans-Ulrich, Wittchen, Sabine M, Apelt, Gerhard, Bühringer, Markus, Gastpar, Markus, Backmund, Jörg, Gölz, Michael R, Kraus, Felix, Tretter, Jens, Klotsche, Jens, Siegert, David, Pittrow, Michael, Soyka   +11 more
openaire   +2 more sources