Results 271 to 280 of about 346,320 (307)

A Multicentre, 4‐Year Mirror‐Image Study Comparing the Effectiveness of Long‐Acting Injectable Antipsychotics in the Treatment of Bipolar Disorder: Results From the LAICO Study

open access: yesBipolar Disorders, Volume 28, Issue 1, February 2026.
ABSTRACT Background This was a 4‐year mirror‐image study of adult patients diagnosed with bipolar disorder (BD) assessing the effects on treatment continuation and hospitalisation between aripiprazole 1‐month (A1M), risperidone‐LAI (R‐LAI) and the monthly and 3‐monthly formulations of paliperidone palmitate (PP1M, PP3M).
Juan Antonio García‐Carmona   +5 more
wiley   +1 more source

Health risks of cocaine adulteration: local anesthetics as modulators of monoamine and organic cation transporters. [PDF]

open access: yesFront Pharmacol
Kudlacek O   +9 more
europepmc   +1 more source

Troriluzole attenuates opioid intake, reinforcing efficacy, seeking behaviours, physical dependence and antinociceptive tolerance in rats

open access: yesBritish Journal of Pharmacology, Volume 183, Issue 3, Page 505-519, February 2026.
Background and Purpose Riluzole, approved for amyotrophic lateral sclerosis (ALS), has a glutamate‐modulating profile favourable for mitigating opioid addiction. It reduces neuronal glutamate release and enhances glutamate reuptake, offering advantages over agents that only increase glutamate reuptake.
Ewa Galaj   +7 more
wiley   +1 more source

Approach Motivation and Reward Sensitivity: Effects of High‐Definition Transcranial Direct Current Stimulation (HD‐tDCS) to Brain Hemispheres on Effort‐Related Cardiovascular Response

open access: yesEuropean Journal of Neuroscience, Volume 63, Issue 3, February 2026.
Brain stimulation over the dorsolateral prefrontal cortex affects effort‐related cardiovascular responses during a mental concentration task of unclear difficulty in presence of moderate incentives. Right cathodal stimulation leads to higher physiological effort compared to left cathodal and sham stimulation.
David Framorando   +2 more
wiley   +1 more source

Changes in social reward across adolescence in male mice. [PDF]

open access: yesSci Rep
Harda Z   +9 more
europepmc   +1 more source

Glutamate Delta 1 Receptor in Synapses, Circuits, and Disease

open access: yesEuropean Journal of Neuroscience, Volume 63, Issue 3, February 2026.
This review discusses our current understanding of the structure–function, expression and roles in neural circuits of the less studied glutamate delta 1 (GluD1) receptor. Converging data suggests many unique features of GluD1 including expression at both excitatory and inhibitory synapses and binding to D‐serine and GABA.
Diane Choi   +3 more
wiley   +1 more source

The rising burden of drug use disorders in the Americas, 2000-2021. [PDF]

open access: yesRev Panam Salud Publica
Martinez R   +6 more
europepmc   +1 more source

EAN 2024 Guideline on the Diagnostic Approach to Oligo/Asymptomatic HyperCKemia

open access: yesEuropean Journal of Neurology, Volume 33, Issue 2, February 2026.
ABSTRACT Background Recent epidemiological studies on the general population reveal that up to 1.3% have oligo/asymptomatic hyperCKemia. Objective This guideline aims to provide updated, evidence‐based recommendations on investigating persons older than 18 years.
T. Kyriakides   +15 more
wiley   +1 more source

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