Results 191 to 200 of about 66,419 (330)

Noninvasive in vivo imaging reveals differences between tectorial membrane and basilar membrane traveling waves in the mouse cochlea

open access: yesProceedings of the National Academy of Sciences of the United States of America, 2015
Hee Yoon Lee   +5 more
semanticscholar   +1 more source

Adverse Effects of Steroid Therapy in Sudden Sensorineural Hearing Loss: A Scoping Review

open access: yesClinical Otolaryngology, EarlyView.
ABSTRACT Objective Sudden sensorineural hearing loss (SSNHL) is an otologic emergency and is treated with steroid therapy. Despite adverse events (AEs) associated with long‐term steroid use being well evidenced, there is sparsity of literature regarding the AEs of short‐course prescriptions in the SSNHL cohort, which limits the quality of patient ...
M. Achanta   +5 more
wiley   +1 more source

Implication of GPRASP2 in the Proliferation and Hair Cell‐Forming of Cochlear Supporting Cells

open access: yesCell Proliferation, EarlyView.
Schematic diagram of GPRASP2‐mediated SCs proliferation and HCs formation. GPRASP2 deficiency results in increased lysosomal degradation of SMO. GPRASP2‐mediated SMO/GLI1 signalling promotes SC proliferation, which contributes to HC formation. GPRASP2‐mediated SMO/β‐catenin signalling is implicated in HCs fate specification and differentiation ...
Jing Cai   +9 more
wiley   +1 more source

Single‐Nucleus Transcriptomics Uncovers Xaf1‐Driven PANoptosis as a Therapeutic Target in Aminoglycoside‐Induced Hearing Loss

open access: yesCell Proliferation, EarlyView.
Neomycin induces increased expression of Xaf1 in cochlear HCs, triggering PANoptosis, which encompasses pyroptosis, apoptosis and necroptosis (left). Targeted Xaf1 knockdown in HCs through gene therapy can significantly inhibit the occurrence of PANoptosis in HCs (right).
Xinlin Wang   +10 more
wiley   +1 more source

Micro-CT Analysis of Rodent Temporal Bones: Identifying Optimal Species for Otological Research. [PDF]

open access: yesLaryngoscope Investig Otolaryngol
Daoudi H   +8 more
europepmc   +1 more source

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