Results 61 to 70 of about 41,682 (330)

Views of reproductive genetic carrier screening participants regarding screening for genes associated with non‐syndromic hearing loss

Prenatal Diagnosis, Volume 42, Issue 13, Page 1658-1666, December 2022., 2022
Abstract Objective Reproductive genetic carrier screening (RGCS) panels often include genes associated with non‐syndromic hearing loss (NSHL) despite a lack of evidence of acceptability. Although some couples take steps to avoid having a child who is deaf, there are effective interventions for children who are deaf.
Lucinda Freeman, Martin B. Delatycki, Jackie Leach Scully, Edwin P. Kirk   +3 more
wiley   +1 more source

The use of nouns by deaf students and students with cochlear implant [PDF]

Revija za Elementarno Izobraževanje, 2017
Cochlear implants have fundamentally changed the rehabilitation and education of deaf people, particularly children. Early operations in children make parents justifiably hopeful that a successful early surgery and hearing and speech rehabilitation may ...
Bojana Globačnik
doaj  

Pinoresinol Diglucoside Attenuates Nuclear Receptor Coactivator 4‐Mediated Ferritinophagy Associated with Cisplatin‐Induced Hearing Loss

Advanced Science, EarlyView.
Pinoresinol diglucoside, a bioactive component extracted from traditional Chinese medicine, attenuates cisplatin‐induced ototoxicity in vivo and in vitro. The protective effect is achieved by downregulation of Socs1. The present study is the first to investigate the expression and function of Socs1 in inner ear, which is known to promote ferroptosis ...
Yin Chen, Cheng Cheng, Ao Li, Dengbin Ma, Siyu Li, Handong Wang, Song Gao, Dingding Liu, Panpan Song, Chenjie Yu, Xiaoyun Qian, Guoqiang Wan, Xia Gao   +12 more
wiley   +1 more source

Cochlear Implantation: An Overview [PDF]

Journal of Neurological Surgery Part B: Skull Base, 2018
AbstractA cochlear implant (CI) is a surgically implanted device for the treatment of severe to profound sensorineural hearing loss in children and adults. It works by transducing acoustic energy into an electrical signal, which is used to stimulate surviving spiral ganglion cells of the auditory nerve.
Eric M. Dowling, Matthew L. Carlson, Daniel Jethanamest, Nicholas L. Deep   +3 more
openaire   +3 more sources

A Multifunctional Nanodelivery System Modified by Fusion Peptides Acts as Teriparatide Carrier for Noise‐Induced Hearing Loss Therapy

Advanced Science, EarlyView.
The fusion peptide LR27‐modified thermosensitive nanodelivery system exhibits both hair cell targeting and inner ear penetrating properties. This system sustainably and effectively delivers PTH1‐34 to the inner ear of a hearing loss mouse model via the synergistic effects of multiple peptides, achieving satisfactory hearing protection through ...
Jiawen Li, Zhuowen Hao, Fangzi Ke, Zhihui Liu, Weilong Wang, Sihui Wen, Fan Wu, Bowen Xu, Miao He, Shengyu Zou, Xiong Chen, Jingfeng Li, Zuhong He   +12 more
wiley   +1 more source

School wellbeing and psychological characteristics of online learning in families of children with and without hearing loss during the Covid‐19 pandemic

Psychology in the Schools, Volume 60, Issue 1, Page 78-104, January 2023., 2023
Abstract This study investigated the psychological characteristics of online learning on Italian students with and without hearing loss (HL) and on their parents, who were forced into isolation during the Covid‐19 pandemic. An online survey collected information on socio‐demographic data and opinions concerning online learning from 61 children (mean ...
Bianca Maria Serena Inguscio, Maria Nicastri, Ilaria Giallini, Antonio Greco, Fabio Babiloni, Giulia Cartocci, Patrizia Mancini   +6 more
wiley   +1 more source

Single Administration of AAV‐mAtp6v1b2 Gene Therapy Rescues Hearing and Vestibular Disorders Caused by Atp6v1b2‐Induced Lysosomal Dysfunction in Hair Cells

Advanced Science, EarlyView.
Wei et al. establish a hair cell‐specific conditional knockout mouse model (Atp6v1b2fl/fl;Atoh1Cre/+), and demonstrate the importance of Atp6v1b2 for hair cell through maintaining the survival of lysosomes. A single administration of AAV‐ie‐Eh3‐mAtp6v1b2 through scala media at P0‐P2 realizes function compensation and restores hearing and balance ...
Gege Wei, Shiwei Qiu, Xue Gao, Lu Zheng, Yijin Chen, Ying Ma, Haifeng Feng, Jinyuan Yang, Guojie Dong, Huiyi Nie, Weihao Zhao, Xiaoge Li, Guangqin Wang, Wei Xiong, Pu Dai, Yongyi Yuan   +15 more
wiley   +1 more source

Long‐Lasting Auditory and Vestibular Recovery Following Gene Replacement Therapy in a Novel Usher Syndrome Type 1c Mouse Model

Advanced Science, EarlyView.
This study shows that gene replacement therapy using the AAV2/Anc80L65 virus can successfully restore hearing and balance in Ush1c knockout mice. The treatment leads to lasting improvements in both auditory and vestibular functions, highlighting its potential as a therapeutic approach for genetic hearing loss and vestibular disorders in humans ...
Weinan Du, Jun Huang, Aizhen Zhang, Fangfang Zhao, Tianwen Chen, Quinn M. McDermott, Tony Zheng, Haibo Wang, Rongli Zhang, Xiaolin Zhang, Jerome Allison, Hong Zhu, Wu Zhou, Qing Yin Zheng   +13 more
wiley   +1 more source

After cochlear implantation: Complications related to flap around implants

Journal of Otology, 2016
Objective: To report complications related to flap around implants after cochlear implantation, possible causes of such complications and treatments. Methods and material: We performed a retrospective analysis of children in whom complications related to
Feifei Qin, Wen Li, Jianxin Qiu, Li Zhang, Mei Zhong   +4 more
doaj   +1 more source

Head shadow enhancement with low-frequency beamforming improves sound localization and speech perception for simulated bimodal listeners [PDF]

, 2017
Many hearing-impaired listeners struggle to localize sounds due to poor availability of binaural cues. Listeners with a cochlear implant and a contralateral hearing aid -- so-called bimodal listeners -- are amongst the worst performers, as both interaural time and level differences are poorly transmitted.
arxiv   +1 more source