Results 61 to 70 of about 429,682 (252)

Transient Sleep Deprivation Induces Persistent Auditory Neuropathy via ROS‐Initiated Neuroinflammation and BK Channel Suppression

open access: yesAdvanced Science, EarlyView.
Sleep disturbance severity closely tracks hearing loss in a clinical cohort, yet the mechanistic link remains unclear. Acute sleep deprivation is shown to trigger transient cochlear oxidative stress that switches into a self‐sustaining neuroinflammatory state, suppressing BK channels and causing irreversible synaptopathy.
Dan Chen   +11 more
wiley   +1 more source

Transcanal approach for implantation of a cochlear nerve electrode array [PDF]

open access: yes, 2013
Objectives/hypothesisTo evaluate a transcanal approach for placement of a stimulating electrode array in the cochlear nerve.Study designProspective cadaveric temporal bone study.MethodsTen human cadaveric temporal bones were dissected.
John C. Middlebrooks   +7 more
core   +1 more source

Frequency-Following Response (FFR) in Military Pilots

open access: yesInternational Archives of Otorhinolaryngology, 2021
Introduction Good hearing in pilots, including central auditory skills, is critical for flight safety and the prevention of aircraft accidents. Pure tone audiometry alone may not be enough to assess hearing in the members of this population who, in ...
Graziela Maria Martins-Moreira   +1 more
doaj   +1 more source

Degeneration in the cochlear nerve of the rat following cochlear lesions

open access: yesBrain Research, 1988
Left unilateral cochlear lesions were performed on 26 albino rats at 1.5 months of age. After survival times ranging from 1 h to 6 months, the animals were perfused via the aorta with mixed aldehydes. Blocks including the cochlear nerves were removed, embedded in Araldite, sectioned in a plane transverse to the longitudinal axis of the nerve, and ...
V, Hoeffding, M L, Feldman
openaire   +2 more sources

Targeting Mitochondrial Redox Signaling Promotes Neuroregeneration and Functional Recovery in a Multiple Sclerosis Model

open access: yesAdvanced Science, EarlyView.
Modulation of mitochondrial redox signaling by furapyrrodole activates CYB5R3 and suppresses Notch signaling, unlocking the regenerative potential of endogenous neural progenitor cells. This approach promotes neurogenesis, oligodendrogenesis, and remyelination, thereby improving neuronal function in a mouse model of multiple sclerosis and identifying ...
Yuki Narushima   +18 more
wiley   +1 more source

The morphology of the oval window in Paranthropus robustus compared to humans and other modern primates

open access: yesThe Anatomical Record, EarlyView.
Abstract The oval window (OW) is an opening connecting the inner and middle ear. Its area has been shown to consistently scale with body mass (BM) in primates, and has been used alongside semi‐circular canal (SCC) size to differentiate Homo sapiens and fossil hominins, including Paranthropus robustus.
Ruy Fernandez, José Braga
wiley   +1 more source

Age-Dependent Auditory Processing Deficits after Cochlear Synaptopathy Depend on Auditory Nerve Latency and the Ability of the Brain to Recruit LTP/BDNF

open access: yesBrain Sciences, 2020
Age-related decoupling of auditory nerve fibers from hair cells (cochlear synaptopathy) has been linked to temporal processing deficits and impaired speech recognition performance. The link between both is elusive.
Philine Marchetta   +9 more
doaj   +1 more source

Bony Cochlear Nerve Canal as a Predictor for Cochlear Nerve Status in Prelingually Deaf Children

open access: yesPRILOZI, 2023
Abstract Objectives : The presence of a functional cochlear nerve is a key issue in the preoperative evaluation of pediatric candidates for cochlear implants. Correlations between cochlear nerve deficiency (CND) and bony abnormalities of the labyrinth or bony canal of the cochlear nerve are not
Marija, Dokoska   +4 more
openaire   +2 more sources

Otopathology in CHARGE syndrome

open access: yesLaryngoscope Investigative Otolaryngology, 2020
Postmortem temporal bone computed tomography (CT) and histopathologic findings in an infant with CHARGE syndrome revealed bilateral cochleovestibular hypoplasia, including cochlear pathology relevant to cochlear implant candidacy.
Jenny X. Chen   +5 more
doaj   +1 more source

EVALUATION OF THE RESULTS OF DIFFERENT PROCEDURES IN COCHLEAR IMPLANTATION. [PDF]

open access: yesZagazig University Medical Journal, 2014
Background: The cochlear implantation has radically changed the outlook for profoundly deaf adults and children. The cochlear implant can provide sufficient hearing sensations to enable most severely or profoundly deafened persons to continue ...
Alaa El-Din El-Feky   +2 more
doaj   +1 more source

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