Results 81 to 90 of about 398,151 (282)

Betahistine exerts a dose-dependent effect on cochlear stria vascularis blood flow in guinea pigs in vivo. [PDF]

, 2012
Betahistine is a histamine H(1)-receptor agonist and H(3)-receptor antagonist that is administered to treat Menière's disease. Despite widespread use, its pharmacological mode of action has not been entirely elucidated. This study investigated the effect
Canis, Martin, Sebastian Strieth, Canis Martin, Kariem Sharaf, Ihler Fritz, Sharaf, Kariem, Strieth, Sebastian, Bertlich, Mattis, Mattis Bertlich, Bertlich Mattis, Ihler, Fritz, Strupp, Michael, Martin Canis, Strupp Michael, Fritz Ihler, Sharaf Kariem, Michael Strupp, Strieth Sebastian   +17 more
core   +1 more source

Redescription of the Triassic cynodont Cistecynodon parvus and reassessment of its phylogeny

The Anatomical Record, EarlyView.
Abstract Cynodontia is an important subclade of Therapsida that first occurred in the late Permian. It includes extinct subclades which are the non‐mammaliaform cynodonts and Mammaliaformes, with the latter ultimately giving rise to crown mammals. The systematics of non‐mammaliaform cynodonts has been extensively studied and is relatively well‐resolved,
Erin S. Lund, Frederik P. Wolvaardt, Roger M. H. Smith, Jaganmoy Jodder, Julien Benoit   +4 more
wiley   +1 more source

FM1-43 reveals membrane recycling in adult inner hair cells of the mammalian cochlea [PDF]

, 2002
Neural transmission of complex sounds demands fast and sustained rates of synaptic release from the primary cochlear receptors, the inner hair cells (IHCs). The cells therefore require efficient membrane recycling.
Ashmore, JF, Griesinger, CB, Richards, CD   +2 more
core  

Oldest well‐preserved euprimate petrosal, from the early Eocene of India (Vastan Lignite Mine, Gujarat)

The Anatomical Record, EarlyView.
Abstract An exquisitely preserved, isolated partial petrosal with associated fragmentary stapes is described from the Vastan Lignite Mine (Gujarat, India), dated to the early Eocene (~54.5 Ma). Several anatomical traits (e.g., large petrosal plate; posterolateral entry of the internal carotid artery to the tympanic cavity; bony tubes surrounding the ...
Mary T. Silcox, Kenneth D. Rose, Rachel H. Dunn, Kishor Kumar, Rajendra S. Rana, Ashok Sahni, Lachham Singh, Thierry Smith, Jordan W. Crowell   +8 more
wiley   +1 more source

Bony cochlear nerve canal and internal auditory canal measures predict cochlear nerve status

, 2017
Objectives:The bony cochlear nerve canal is the space between the fundus of the internal auditory canal and the base of the cochlear modiolus that carries cochlear nerve fibres.
Mocan, B. O., L Sennaroğlu, Atay, G., Tahir, E., Bajin, M. D., M D Bajin, Sennaroglu, L., B Ö Mocan, G Atay, E Tahir   +9 more
core   +1 more source

Histamine and the mechanisms of nausea and vomiting: Translating the uncertain pharmacology of cyclizine

British Journal of Clinical Pharmacology, EarlyView.
Abstract Cyclizine is a long‐established, short‐acting drug, registered for preventing motion sickness, post‐operative nausea and vomiting (PONV) and ‘vomiting of known cause’. The latter is not defined but may include pregnancy and patients receiving palliative care, historically accepted without large, controlled trials.
Gareth J. Sanger, Paul L. R. Andrews
wiley   +1 more source

Does Cochlear Nerve Size Differ Among Societies?

, 2015
Objective: Cochlear nerve size is a prognostic factor for successful cochlear implantation. Reports about the cochlear nerve size in normal-hearing patients and differences among societies in the cochlear nerve size are not satisfactory.
Imamoglu, Hakan, Umit Erkan Vurdem, Durmus, Kasim, Dogan, Mansur, Kasim Durmus, ERKOÇ, Mustafa Fatih, VURDEM, Umit Erkan, Aydemir, Eylem Itir, Hakan Imamoglu, Mustafa Fatih Erkoc, Mavili, Ertuğrul, Ertugrul Mavili, Eylem Itir Aydemir, Mansur Dogan   +13 more
core   +3 more sources

Classification and Current Management of Inner Ear Malformations

Balkan Medical Journal, 2017
Morphologically congenital sensorineural hearing loss can be investigated under two categories. Majority of the congenital hearing loss (80%) are membranous malformations. Here the pathology involves inner ear hair cells.
Levent Sennaroğlu, Münir Demir Bajin
doaj   +1 more source

Role of SoxE transcription factors in development and disease

Developmental Dynamics, EarlyView.
Abstract Sox8, Sox9, and Sox10 arose by multiple rounds of genome duplications from a single SoxE gene in ancestral vertebrates. In this review, we will briefly discuss the molecular structure and function of SoxE transcription factors and their evolutionary origin. We will then discuss their expression, function, and developmental disorders.
Merin Lawrence, Gerhard Schlosser
wiley   +1 more source

Development of a feline model for preclinical research of a new translabyrinthine auditory nerve implant

Frontiers in Neuroscience
Cochlear implants are among the most successful neural prosthetic devices to date but exhibit poor frequency selectivity and the inability to consistently activate apical (low frequency) spiral ganglion neurons. These issues can limit hearing performance
W. Mitchel Thomas, Steven A. Zuniga, Inderbir Sondh, Moritz Leber, Florian Solzbacher, Florian Solzbacher, Thomas Lenarz, Hubert H. Lim, Hubert H. Lim, David J. Warren, David J. Warren, Loren Rieth, Meredith E. Adams   +12 more
doaj   +1 more source