Results 91 to 100 of about 920,707 (289)

Transforming Brain Health With Neurotechnology Convergence (Part II): Intelligent Neurointervention Systems for Neurological Disorders

open access: yesBrain Health, EarlyView.
ABSTRACT Neurological disorders represent a critical domain within global health, necessitating advanced interventions to address complex pathologies such as tumors, functional disorders, and cerebrovascular diseases. Despite the proven benefits of early intervention, current treatment paradigms face significant challenges: (1) limited precision in ...
Qing Ye   +14 more
wiley   +1 more source

The segregation of Calb1, Calb2, and Prph neurons reveals distinct and mixed neuronal populations and projections to hair cells in the inner ear and central nuclei

open access: yesDevelopmental Dynamics, EarlyView.
Three populations of hair cells have a distinct expression of Calb1 and Calb2. (A, A′D) The central is highly positive for Calb1 while surrounding HC are positive for Calb2. Later, a calyx forms primarily with Calb1. (B, B′, D′, D″) Saccule and utricle start out positive for Calb2 but will upregulate the Calb1 in the striola that is primarily forming ...
Jeong Han Lee   +6 more
wiley   +1 more source

Immunohistopathology of Cochleovestibular Schwannoma in Human Temporal Bone Specimens

open access: yesBiology
The aim of this study was to investigate the pathology of hearing loss caused by cochleo-vestibular schwannoma. Surgical specimens have demonstrated that a tumor may displace normal nerve fibers of the cochlear nerve to one side (pushing pattern) or the ...
Jennifer T. O’Malley   +5 more
doaj   +1 more source

The Development of a Single Frequency Place in the Mammalian Cochlea: The Cochlear Resonance in the Mustached Bat Pteronotus parnellii [PDF]

open access: yes, 2003
Cochlear microphonic potentials (CMs) were recorded from the sharply tuned, strongly resonant auditory foveae of 1- to 5-week-old mustached bats that were anesthetized with Rompun and Ketavet.
Drexl, Markus   +4 more
core   +2 more sources

Role of SoxE transcription factors in development and disease

open access: yesDevelopmental Dynamics, EarlyView.
Abstract Sox8, Sox9, and Sox10 arose by multiple rounds of genome duplications from a single SoxE gene in ancestral vertebrates. In this review, we will briefly discuss the molecular structure and function of SoxE transcription factors and their evolutionary origin. We will then discuss their expression, function, and developmental disorders.
Merin Lawrence, Gerhard Schlosser
wiley   +1 more source

The local translation of KNa in dendritic projections of auditory neurons and the roles of KNa in the transition from hidden to overt hearing loss [PDF]

open access: yes, 2019
Local and privileged expression of dendritic proteins allows segregation of distinct functions in a single neuron but may represent one of the underlying mechanisms for early and insidious presentation of sensory neuropathy.
Chiamvimonvat, Nipavan   +8 more
core   +1 more source

Assembly of the Auditory Circuitry by a Hox Genetic Network in the Mouse Brainstem [PDF]

open access: yes, 2013
Rhombomeres (r) contribute to brainstem auditory nuclei during development. Hox genes are determinants of rhombomere-derived fate and neuronal connectivity.
Andolfi, G.   +9 more
core   +5 more sources

Understanding the Symptom Burden of Complex Skull Base Tumors From the Patient's Perspective

open access: yesHead &Neck, EarlyView.
ABSTRACT Background Symptom burden of skull base tumor (SBT) patients, especially those undergoing multimodality treatment, is poorly understood. We aim to understand symptom burden in this patient group using the core module the MD Anderson Symptom Inventory (MDASI).
Shirley Y. Su   +8 more
wiley   +1 more source

Analysis of electrically evoked compound action potential of the auditory nerve in children with bilateral cochlear implants

open access: yesBrazilian Journal of Otorhinolaryngology, 2016
INTRODUCTION: The cochlear implant device has the capacity to measure the electrically evoked compound action potential of the auditory nerve. The neural response telemetry is used in order to measure the electrically evoked compound action potential of ...
Fernanda Ferreira Caldas   +6 more
doaj   +1 more source

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