Results 91 to 100 of about 23,205 (193)

Causal relationship between type 2 diabetes and glioblastoma: bidirectional Mendelian randomization analysis

open access: yesScientific Reports
As the prevalence of Type 2 Diabetes Mellitus (T2DM) and Glioblastoma (GBM) rises globally, the relationship between T2DM and GBM remains controversial. This study aims to investigate whether genetically predicted T2DM is causally associated with GBM. We
Wei Chen, Taoyuan Zhang, Hui Zhang
doaj   +1 more source

Return to sport after meniscectomy, meniscal repair, and meniscal allograft transplantation for meniscal lesions in athletes: A systematic review and meta‐analysis

open access: yesKnee Surgery, Sports Traumatology, Arthroscopy, EarlyView.
Abstract Purpose The aim of this systematic review and meta‐analysis was to quantify and compare the evidence on the results obtained with the surgical treatments for meniscal lesions in athletes. Methods A literature search was conducted on PubMed, Cochrane and Web of Science in August 2025 according to the PRISMA guidelines.
Alessandro Bensa   +5 more
wiley   +1 more source

Imaging modalities demonstrate moderate and heterogeneous diagnostic accuracy for periprosthetic joint infection: A systematic review and meta‐analysis

open access: yesKnee Surgery, Sports Traumatology, Arthroscopy, EarlyView.
Abstract Purpose The diagnostic accuracy of imaging modalities in periprosthetic joint infections (PJIs) remains uncertain. This study assessed and compared the performance of different imaging techniques for diagnosing PJI. Methods A systematic review and meta‐analysis of studies published in PubMed and Embase (1 January 2000 to 1 March 2024) was ...
Armita Armina Abedi   +4 more
wiley   +1 more source

Olfactory Dysfunction and Metabolic Syndrome Components: A Systematic Review and Meta‐Analysis

open access: yesThe Laryngoscope, EarlyView.
ABSTRACT Objective To elucidate the association between olfactory dysfunction (OD) and metabolic syndrome components. Data Sources PubMed (National Library of Medicine—National Institutes of Health), Scopus (Elsevier), CINAHL Complete (EBSCOhost), and the Cochrane Library (Wiley) databases were searched from inception through March 23rd, 2026.
Neeti Gandra   +6 more
wiley   +1 more source

Maxillomandibular Advancement Outcomes in Obstructive Sleep Apnea by Age and Gender

open access: yesThe Laryngoscope, EarlyView.
This systematic review and meta‐analysis of 36 studies (608 patients) found that maxillomandibular advancement significantly improves polysomnographic, cephalometric, and subjective measures of obstructive sleep apnea across both sexes and throughout the lifespan. Odds of surgical cure decline roughly 3% per year of age.
Matthew O. Herbst   +7 more
wiley   +1 more source

Contributions of Vegetation Restoration to Soil Organic Carbon Sequestration in Deserts of China: A Meta‐Analysis

open access: yesLand Degradation &Development, EarlyView.
ABSTRACT Vegetation restoration has been widely used to curb desertification in northern and central desert shifting sandy lands of China. However, the general pattern, variability, and drivers of its effects on soil organic carbon (SOC) remain unclear.
Benmo Li   +4 more
wiley   +1 more source

Topographic and Climatic Determinants of Soil Organic Carbon Across Landscapes: A Meta‐Analysis

open access: yesLand Degradation &Development, EarlyView.
ABSTRACT The soil is the greatest natural store of organic carbon, holding between 1500 to 1550 Pg C of organic carbon at the top 100 cm of the soil globally—roughly twice the carbon pool in the atmosphere. The spatial distribution of this stock is controlled by a complex chain of controls: topographic position regulates the hydrological redistribution,
Vishal Sharma   +8 more
wiley   +1 more source

Placebo Effect in Levodopa‐Induced Dyskinesia: A Systematic Review and Meta‐Analysis

open access: yesMovement Disorders Clinical Practice, EarlyView.
Abstract Background Levodopa‐induced dyskinesia (LID) is a complication of Parkinson's disease (PD) treatment. While the placebo effect is a known component in PD clinical trials, its specific magnitude in the context of LID is not well characterized.
Luiz Vinicius Silva Correa   +5 more
wiley   +1 more source

Staged Bilateral Magnetic Resonance‐Guided Focused Ultrasound for Treating Essential Tremor: Systematic Review and Meta‐Analysis

open access: yesMovement Disorders Clinical Practice, EarlyView.
Abstract Background Unilateral magnetic resonance guided focused ultrasound (MRgFUS) thalamotomy reduces tremor in essential tremor, yet disability often persists on the untreated side. The added benefit and safety of a staged contralateral lesion remain uncertain.
Nima Norbu Sherpa   +7 more
wiley   +1 more source

Mapping Causal Biology: Mendelian Randomization in the Era of Big Data

open access: yesMed Research, EarlyView.
Mendelian randomization (MR) leverages genetic variants to mitigate confounding biases in causal inference. This review systematically maps MR's methodological evolution, highlights its expanding applications in epidemiology and drug target validation, and outlines future directions for overcoming current biases through dynamic, multi‐omics, and cross ...
Xuanlu Shen   +10 more
wiley   +1 more source

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