Results 81 to 90 of about 23,205 (193)

Bidirectional mendelian randomization assessment of causality between lactate levels and multiple autoimmune diseases

Scientific Reports
Bidirectional two-sample Mendelian randomization (MR) was performed to provide genetic evidence for the causal association between multiple sclerosis (MS), type 1 diabetes(T1D), rheumatoid arthritis (RA) and inflammatory bowel disease (IBD), Crohn’s ...
Hua Fan, Hongna Song, Qizhi Fu, Ganqin Du, Yongjie Bai, Canfei Zhang, Xiaofei Shi   +6 more
doaj   +1 more source

Neuroprotective effects of quercetin in animal models of neurodegenerative diseases: A systematic review and meta‐analysis

Journal of the Science of Food and Agriculture, EarlyView.
Abstract Neurodegenerative conditions such as Alzheimer's disease and Parkinson's disease are characterized by progressive neuronal loss driven by oxidative stress and inflammation. Quercetin, a dietary flavonoid with established antioxidant and anti‐inflammatory properties, has emerged as a potential neuroprotective agent.
In Ho Cho, Hendra Mahakam Putra, Cheol Woon Jung, Gyu Hwan Hyun, Hwan‐Hee Jang, In Guk Hwang, Sung Won Kwon   +6 more
wiley   +1 more source

Serum uric acid levels and intracerebral hemorrhage: A two-sample Mendelian randomization study

Journal of Stroke and Cerebrovascular Diseases
Objective: Previous observational studies have generated controversy regarding the correlation between serum uric acid (UA) levels and intracerebral hemorrhage (ICH), with the causal relationship remaining uncertain.
Buyou Lu, Xiaorui Sun, Qi Zhong, Zijiu Sun   +3 more
doaj   +1 more source

Timing Matters: A Meta‐Analysis of BREAST‐Q Administration in Tissue‐Expander and Implant‐Based Breast Reconstruction

Journal of Surgical Oncology, EarlyView.
ABSTRACT Background BREAST‐Q is the most widely used patient‐reported outcome measure following breast reconstruction, yet no consensus exists on optimal timing or duration of administration. We analyzed BREAST‐Q follow‐up after implant‐based reconstruction, comparing direct‐to‐implant (DTI) and two‐stage tissue expander (TE), to determine how outcomes
Emanuella M. Brito, Isabel Bernal, Sean K. Park, Julia L. Armstrong, Natalia Correa, Anthony Pasarin, Anastasia Tousimis, Graham S. Schwarz, Martin I. Newman   +8 more
wiley   +1 more source

Protective role of gout against colorectal cancer: a Mendelian randomization study

Discover Oncology
Background The battle against cancer is often hindered by the complex mechanisms of drug resistance, a key challenge in treatment. In this context, the inflammatory condition gout, characterized by hyperuricemia, has shown potential protective effects ...
Xia Pan, Yong’an Liu, Xiaoming Zhang, Yan Meng   +3 more
doaj   +1 more source

Feasibility and Reproducibility of a Structure‐Guided Deep Learning Model for Automatic Detection of the Standard Sagittal Plane in First‐Trimester Nuchal Translucency Assessment Using 3D Ultrasound

Journal of Ultrasound in Medicine, EarlyView.
Objectives Accurate nuchal translucency (NT) measurement for assessing the risk of fetal genetic abnormalities requires precise acquisition of the mid‐sagittal plane (MSP). However, achieving an appropriate MSP is technically challenging due to anatomical variability and operator dependence inherent in conventional 2‐dimensional (2D) ultrasound.
Hayan Kwon, Hyewon Hur, Hyun Cheol Cho, Yun ji Jung, Suhra Kim, Ja‐Young Kwon   +5 more
wiley   +1 more source

Vitiligo and Skin Cancer Risk: A Systematic Review and Meta‐Analysis With Subtype and Phototherapy Stratification

JEADV Clinical Practice, EarlyView.
Vitiligo was associated with directionally lower odds of melanoma and non‐melanoma skin cancer in this systematic review and meta‐analysis of 14 studies. A statistically significant inverse association was observed for squamous cell carcinoma. Phototherapy exposure showed higher, but non‐significant, point estimates for melanoma and non‐melanoma skin ...
Simonetta I. Gaumond, Luis F. Andrade, Peyton V. Warp, Isabella Kamholtz, Sophie Shrestha, Hannah Metheny, Alireza Abdshah, Paolo Romanelli, Joaquin J. Jimenez   +8 more
wiley   +1 more source

Causal relationships of total testosterone and bioavailable testosterone with aortic aneurysm: A Mendelian randomization study

陆军军医大学学报
Objective To explore the causal relationships between plasma total testosterone (TT), bioavailable testosterone (Bio-T) levels and the pathogenesis of aortic aneurysm (AA) using Mendelian randomization (MR).
HOU Liwen, HOU Liwen, WANG Ying
doaj   +1 more source

Functional alignment in robotic total knee arthroplasty provides favourable outcomes and minimal early revisions: A systematic review and meta‐analysis

Knee Surgery, Sports Traumatology, Arthroscopy, EarlyView.
Abstract Purpose Functional alignment (FA) has emerged as a personalised alignment strategy in total knee arthroplasty (TKA), enabled by robotic‐assisted technology. Although early clinical results are encouraging, evidence remains heterogeneous and long‐term safety is uncertain.
Vasileios Giovanoulis, Angelo V. Vasiliadis, Luca Andriollo, Pietro Gregori, Konstantinos Dretakis, Christos Koutserimpas, Sébastien Lustig   +6 more
wiley   +1 more source

Comparison of the Effectiveness of Interventions to Reduce Smoking in Ecuadorian Patients with Cardiovascular Diseases

Medisur
Foundation: cardiovascular diseases are the main cause of death worldwide. Tobacco consumption constitutes a relevant risk factor. There are numerous therapeutic proposals from different health disciplines with the aim of facilitating the transition from
Elsy Labrada González, Angélica Victoria Martínez Herrera, Manuel Conrado Ezcurdia Bárzaga   +2 more
doaj