Results 11 to 20 of about 23,205 (193)
Relationship between NAFLD and coronary artery disease: A Mendelian randomization study
Hepatology, EarlyView., 2022 Abstract Background and Aims There is an ongoing debate on whether NAFLD is an active contributor or an innocent bystander in the pathogenesis of coronary artery disease (CAD). The aim of the present study was to assess the causal relationship between NAFLD and CAD.
Zhewen Ren +4 more
wiley +1 more source
Additional file 3 of An accurate test for homogeneity of odds ratios based on Cochranâ s Q-statistic
, 2015 Description of the R program for computing the homogeneity test Q Îł .
Kulinskaya, Elena, Dollinger, Michael
openaire +1 more source
Rheumatoid arthritis and coronary atherosclerosis: a two-sample Mendelian randomization study
Frontiers in Cardiovascular Medicine, 2023 ObjectivesThe relationship between rheumatoid arthritis (RA) and coronary atherosclerosis is widely concerned, but observational studies have not clarified causality.
Qiong Nie +5 more
doaj +1 more source
Effects of Hyperthyroidism on Venous Thromboembolism: A Mendelian Randomization Study
Journal of Immunology Research, 2022 Objective. Observational studies show the correlation between thyroid dysfunction and risk of venous thromboembolism. However, the causal effects remain uncertain. Our study was conducted to evaluate whether thyroid function and dysfunction were causally
Fushi Han +5 more
doaj +1 more source
Frontiers in Neurology, 2022 BackgroundObservational studies have suggested that hearing impairment (HI) was associated with the risk of falls, but it remains unclear if this association is of causal nature.MethodsA two-sample Mendelian randomization (MR) study was conducted to ...
Jun Wang +8 more
doaj +1 more source
Mendelian randomization study on the relationship between fibroblast growth factors and their receptors and the risk of spontaneous abortion [PDF]
Yixue xinzhi zazhiObjective To investigate the causal relationship between fibroblast growth factors (FGFs), their receptors (FGFRs) and spontaneous abortion (SA). Methods FGFs, FGFRs, and SA related GWAS data were obtained from the FinnGen Alliance and Genome-wide ...
LI Jing +6 more
doaj +1 more source
Tumor B‐cell infiltration in platinum‐treated advanced muscle‐invasive urothelial carcinoma
Molecular Oncology, EarlyView.Bladder tumors with higher pretreatment memory B‐cell infiltration were linked to longer survival after cisplatin chemotherapy, but not carboplatin. These tumors also showed more organized immune structures (tertiary lymphoid structures) and a shared pro‐inflammatory B‐cell‐rich community, suggesting that memory B cells may help identify patients most ...
Konrad Stawiski +10 more
wiley +1 more source
The Role of Calcitonin Gene‐Related Peptide in High‐Altitude Headache: A Prospective Field Study
Annals of Clinical and Translational Neurology, EarlyView.ABSTRACT Objective High‐altitude headache (HAH) is a common neurological condition associated with rapid ascent to high altitude. The pathophysiological mechanisms underlying HAH remain incompletely understood. Calcitonin gene‐related peptide (CGRP), a neuropeptide implicated in migraine pathophysiology, may play a key role in the pathophysiology of ...
Roman Schniepp +4 more
wiley +1 more source
Advanced Science, EarlyView.This study reveals a metabolic signaling axis in the OSCC microenvironment where palmitic acid (PA) drives the activation of CAFs. PA uptake triggers CEBPG‐dependent epigenetic remodeling to upregulate ERN1 and TMBIM6, thereby mitigating ER stress. This adaptive program sustains CAF survival and the pro‐metastatic phenotype, establishing this pathway ...
Yiling Duan +6 more
wiley +1 more source
Renal FailureBackground There is a close clinical association between hypothyroidism and nephrotic syndrome (NS) was close, but whether there is genetic causality between the two is not known.Objective Using pooled data from a genome-wide association study (GWAS ...
Can Liu +4 more
doaj +1 more source