Results 41 to 50 of about 23,205 (193)

Coeliac disease and postpartum depression: are they linked? A two-sample Mendelian randomization study

Frontiers in Psychiatry
BackgroundTo explore the potential causal associations between coeliac disease(CD) and postpartum depression(PPD) by using two-sample Mendelian randomization(MR) analysis.MethodsThe IEU OPEN GWAS project was utilized to identify genetic loci strongly ...
Xiaomeng Yu, Mosong Cheng, Jindan Zheng
doaj   +1 more source

Causal correlations between inflammatory proteins and heart failure: A two‐sample Mendelian randomization analysis

ESC Heart Failure, Volume 12, Issue 2, Page 1374-1385, April 2025.
Abstract Aims Inflammation plays a critical role in both the development and progression of heart failure (HF), which is a leading cause of morbidity and mortality worldwide. However, the causality between specific inflammation‐related proteins and HF risk remains unclear.
Xian‐Guan Zhu, Gui‐Qin Liu, Ya‐Ping Peng, Li‐Ling Zhang, Xian‐Jin Wang, Liang‐Chuan Chen, Yuan‐Xi Zheng, Xue‐Jun Xiang, Rui Qiao, Xian‐He Lin   +9 more
wiley   +1 more source

Association between systemic lupus erythematosus and osteoporosis: a mendelian randomization analysis

BMC Rheumatology
Background Systemic Lupus Erythematosus (SLE) and Osteoporosis are two prevalent medical conditions. Previous studies have suggested a possible correlation between SLE and osteoporosis, though the underpinning causal relationship remains largely unknown.
Danfeng Xu, Bing Wu
doaj   +1 more source

Mendelian randomization study of childhood asthma and chronic obstructive pulmonary disease in European and East Asian population

World Allergy Organization Journal
Objective: The present study aimed to explore the potential causal relationship between childhood asthma and chronic obstructive pulmonary disease (COPD) in European and East Asian populations with Mendelian randomization (MR) analysis. Methods: Based on
Guo Zhen Fan, PhD, Ke Yang Chen, MD, Xiao Meng Liu, MD, Zheng Hai Qu, MD   +3 more
doaj   +1 more source

Clinical significance of subclinical seizures in epilepsy presurgical evaluation: A systematic review and meta‐analysis

Epilepsia, EarlyView.
Abstract Objective Subclinical seizures (SCSs) remain an understudied aspect of presurgical evaluation in patients with drug‐resistant epilepsy (DRE), with uncertain prevalence, distribution among epilepsy types, and predictive value for surgical outcomes.
Pilar Bosque‐Varela, Panagiota‐Eleni Tsalouchidou, Petra Levicka, Lara Wadi, Elizabeth R. Blackwood, Eugen Trinka, Birgit Frauscher   +6 more
wiley   +1 more source

Hepatic Mechanisms and Therapeutic Target Underpinning Hypercoagulation in Obesity: Insights From Genetic and Transcriptomic Analyses

Exploration, EarlyView.
Obesity‐linked hypercoagulation is driven by fibrinogen overproduction in a specific hepatocyte cluster via IL6 signalling. Genetic and mechanistic studies reveal this pathway as a key target for therapies to mitigate clotting risks and associated complications in obese individuals.
Shumin Li, Gengchen Feng, Xin Huang, Xiao Teng, Ziyi Yang, Yue Liu, Yonghui Jiang, Tao Zhu, Teng Liu, Yunfei Xu, Chang Pan, Han Zhao, Shaozhuang Liu, Shigang Zhao, Zi‐Jiang Chen   +14 more
wiley   +1 more source

Fungitoxic Potential of Secondary Eucalyptus Metabolites in the Inhibition of Neopestalotiopsis clavispora Isolated From Macadamia

Flavour and Fragrance Journal, EarlyView.
Fungi cause injury in forest plantations; then it was tested the fungitoxic potential of Corymbia citriodora, Eucalyptus camaldulensis and Eucalyptus urophylla leaves for inhibiting the mycelial growth of the Neopestalotiopsis clavispora fungus. The presence of citronellal and citronellol compounds in the C. citriodora essential oil was more associated
Dalton Longue Júnior, Catia dos Santos Libarino, Quelmo Silva de Novaes, Patrícia Baier Krepsky, Gabriela Nunes Santana, Bruno Oliveira Moreira, Laura da Silva Rocha, Victor Vinicius Sousa Martinelli Sales   +7 more
wiley   +1 more source

Cochran's Q Test of Stimulus Overselectivity within the Verbal Repertoire of Children with Autism. [PDF]

Perspect Behav Sci, 2022
Mason L, Otero M, Andrews A.
europepmc   +1 more source

Multi‐Cohort Analysis Reveals Genetic Predispositions to Clonal Hematopoiesis as Mutation‐Specific Risk Factors for Stroke

Advanced Genetics, Volume 6, Issue 1, March 2025.
This study comprehensively evaluated the differential effect of clonal hematopoiesis (CH) mutations on the risk of various stroke subtypes and functional recovery. It shows that TET2 is associated with small vessel stroke possibly via a pro‐inflammatory pathway. Abstract Recent observational studies have found an association between Clonal Hematopoesis
Shuyang Lin, Yang E. Li, Yan Wang
wiley   +1 more source

Causal relationship between genetic proxies for calcium channel blockers and the risk of depression: a drug-target Mendelian randomization study

Frontiers in Psychiatry
BackgroundCalcium channel blockers (CCBs) are widely used in the clinical management of hypertension. Depression, a common comorbidity of hypertension, is an important issue in the management of hypertension.
Chaoyi Ye, Chaoyi Ye, Chaoyi Ye, Chaoyi Ye, Chaoyi Ye, Chaoyi Ye, Tingjun Wang, Tingjun Wang, Tingjun Wang, Tingjun Wang, Tingjun Wang, Huajun Wang, Huajun Wang, Huajun Wang, Huajun Wang, Huajun Wang, Guili Lian, Guili Lian, Guili Lian, Guili Lian, Guili Lian, Liangdi Xie, Liangdi Xie, Liangdi Xie, Liangdi Xie, Liangdi Xie   +25 more
doaj   +1 more source