Results 41 to 50 of about 25,534 (196)

Multi‐Cohort Analysis Reveals Genetic Predispositions to Clonal Hematopoiesis as Mutation‐Specific Risk Factors for Stroke

Advanced Genetics, Volume 6, Issue 1, March 2025.
This study comprehensively evaluated the differential effect of clonal hematopoiesis (CH) mutations on the risk of various stroke subtypes and functional recovery. It shows that TET2 is associated with small vessel stroke possibly via a pro‐inflammatory pathway. Abstract Recent observational studies have found an association between Clonal Hematopoesis
Shuyang Lin, Yang E. Li, Yan Wang
wiley   +1 more source

Association between systemic lupus erythematosus and osteoporosis: a mendelian randomization analysis

BMC Rheumatology
Background Systemic Lupus Erythematosus (SLE) and Osteoporosis are two prevalent medical conditions. Previous studies have suggested a possible correlation between SLE and osteoporosis, though the underpinning causal relationship remains largely unknown.
Danfeng Xu, Bing Wu
doaj   +1 more source

Mendelian randomization study of childhood asthma and chronic obstructive pulmonary disease in European and East Asian population

World Allergy Organization Journal
Objective: The present study aimed to explore the potential causal relationship between childhood asthma and chronic obstructive pulmonary disease (COPD) in European and East Asian populations with Mendelian randomization (MR) analysis. Methods: Based on
Guo Zhen Fan, PhD, Ke Yang Chen, MD, Xiao Meng Liu, MD, Zheng Hai Qu, MD   +3 more
doaj   +1 more source

Coeliac disease and postpartum depression: are they linked? A two-sample Mendelian randomization study

Frontiers in Psychiatry
BackgroundTo explore the potential causal associations between coeliac disease(CD) and postpartum depression(PPD) by using two-sample Mendelian randomization(MR) analysis.MethodsThe IEU OPEN GWAS project was utilized to identify genetic loci strongly ...
Xiaomeng Yu, Mosong Cheng, Jindan Zheng
doaj   +1 more source

Oral and Fecal Microbial Dysbiosis as Non‐Invasive Diagnostic Biomarkers for Gastrointestinal Cancers: A Systematic Review and Meta‐Analysis of Diagnostic Accuracy

International Journal of Cancer, EarlyView.
ABSTRACT Gastrointestinal (GI) cancers, including esophageal (EC), gastric (GC), and colorectal cancer (CRC), impose a substantial global burden, with early detection remaining crucial for improving patient outcomes. The oral and gut microbiota are increasingly implicated in cancer development and hold promise as sources of non‐invasive biomarkers ...
Saidi Hu, Zhouyan Chen, Yanxia Li, Qingyan Liao, Mingdong Luo, Danyang Song, Hanyue Yu, Yuetong Gao, Shuanglong Yang, Siran Wan, Shunhong Zhang, Chenchen Luo, Lin‐Yong Zhao   +12 more
wiley   +1 more source

The mitochondrial DNA copy number and ovary‐related reproductive disorders: A bidirectional two‐sample Mendelian randomization study

International Journal of Gynecology &Obstetrics, Volume 169, Issue 1, Page 112-120, April 2025.
Abstract Objective In the present study, a bidirectional two‐sample Mendelian randomization approach was utilized to explore potential causal relationships between mitochondrial DNA copy number (mtDNA‐CN) and ovary‐related reproductive disorders (ORRDs), including ovarian dysfunction, ovarian cyst, polycystic ovary syndrome (PCOS), premature ovarian ...
Ke Peng, Xiao Han, Congquan Wu, Qiaowen Lu, Shujun Gao   +4 more
wiley   +1 more source

Cochran's Q Test of Stimulus Overselectivity within the Verbal Repertoire of Children with Autism. [PDF]

Perspect Behav Sci, 2022
Mason L, Otero M, Andrews A.
europepmc   +1 more source

The role of large language models as screening assistants in the diagnosis of placenta accreta spectrum pathologies

International Journal of Gynecology &Obstetrics, EarlyView.
Abstract Objective Large language models (LLMs) are increasingly utilized in modern medicine. In obstetrics, their ability to interpret complex imaging, such as ultrasound images for placenta accreta spectrum (PAS), remains largely unexplored. This study aimed to investigate the capacity of multimodal LLMs to interpret sonographic images of placentae ...
Iason Psilopatis, Heidrun Schoenberger, Annkatrin Butenschoen, Thabea K. Musik, Georgia Levidou, Beatrice Mosimann, Gwendolin Manegold‐Brauer   +6 more
wiley   +1 more source

Correction to: Cochran's Q Test of Stimulus Overselectivity within the Verbal Repertoire of Children with Autism. [PDF]

Perspect Behav Sci, 2022
Mason L, Otero M, Andrews A.
europepmc   +1 more source

Shared Genetic Pathways Linking Oral Diseases to Gastrointestinal Disorders: An Integrative Multi‐Omics Study

iMetaMed, EarlyView.
Shared genetics pathways connect oral diseases and gut disorders. ABSTRACT Oral diseases are highly prevalent and increasingly recognized as contributors to gastrointestinal disorders. Despite clinical observations of oral–gut comorbidity, the underlying genetic architecture and causal mechanisms remain poorly understood.
Rui Zhang, Yuelan Gao, Yuyang Zhao, Wanyang Zhong, Xingxiang Duan, Yan He, Qingsong Ye   +6 more
wiley   +1 more source