Results 71 to 80 of about 133,391 (266)

Efficacy and safety of gantenerumab in the treatment of Alzheimer's disease: A meta-analysis of randomized controlled trials

Archives of Gerontology and Geriatrics Plus
Introduction: Gantenerumab has garnered considerable attention for its potential to modify the natural course of Alzheimer's disease. However, recent studies have shown mixed results for the use of this medication for the treatment of Alzheimer's Disease.
Milene Vitória Sampaio Sobral, Victor Gonçalves Soares, Ocilio Ribeiro Gonçalves, Victoria Städler de Abreu, Lucas Cael Azevedo Ramos Bendaham, Brenda Leticia Lopes Batista, M.D., Marco Antonnio Rocha dos Santos, M.D., MsC   +6 more
doaj   +1 more source

Clinical Significance of Therapeutic Drug Level Monitoring for Mycophenolate in Patients With Extrarenal Systemic Lupus Erythematosus—A Systematic Review and Meta‐Analysis

Arthritis Care &Research, EarlyView.
Objective Clinical response to mycophenolic acid (MPA) is highly heterogeneous; thus, therapeutic drug level monitoring (TDM) may help improve treatment efficacy. This systematic review and meta‐analysis examined therapeutic ranges for MPA levels associated with better outcomes and safety in patients with systemic lupus erythematosus (SLE ...
Zahraa Qamhieh, Dalia Sriwi, Callie Saric, Tripti Singh, Christie M. Bartels, Shivani Garg   +5 more
wiley   +1 more source

Forecasting the term structure of government bond yields [PDF]

, 2002
Despite powerful advances in yield curve modeling in the last twenty years, comparatively little attention has been paid to the key practical problem of forecasting the yield curve. In this paper we do so.
Canlin Li, Canlin Li, Francis X. Diebold, Francis X. Diebold, Jan Pieter Krahnen, Prof Dr   +5 more
core   +6 more sources

Lyophilized Synthetic Platelets: In Vitro Characterization and in Vivo Evaluation in Mouse Thrombocytopenia Model

Advanced Science, EarlyView.
ABSTRACT Platelet transfusions to treat bleeding complications use donor‐derived platelets stored at room‐temperature, that have a shelf‐life of only 5–7 days due to bacterial contamination risks. Cold‐stored and freeze‐dried platelets are being investigated for extending shelf‐life, but these still have the inherent challenge of donor‐dependency.
Ujjal Didar Singh Sekhon, Dante Disharoon, Shrijal S. Desai, Baylee Traylor, Emily Gahagan, Emma Quill, Kristin Aldridge, Norman F. Luc, Sonali Rohiwal, Shruti Raghunathan, Rebecca Ahn, Sana Syed, Alexander Dornback, Bipin Chakravarthy Paruchuri, Andrew Ditto, Susan M. Shea, Philip C. Spinella, Matthew D. Neal, Michael A. Bruckman, Christa L. Pawlowski, Anirban Sen Gupta   +20 more
wiley   +1 more source

On the Economics of US Agricultural Policy

Applied Economic Perspectives and Policy, EarlyView.
ABSTRACT This paper presents an economic analysis of US agricultural policy, building on a modified version of Gardner's efficient redistribution. We argue that agricultural policy is motivated as an attempt to implement an efficient redistribution scheme that redistributes income toward farmers who, as a group, have been adversely affected by ...
Jean‐Paul Chavas
wiley   +1 more source

The limits to stock return predictability [PDF]

, 2009
We examine predictive return regressions from a new angle. We ask what observable univariate properties of returns tell us about the “predictive space” that defines the true predictive model: the triplet ¡ λ, R2 x, ρ¢ , where λ is the predictor’s ...
Robertson, D., Wright, Stephen
core  

Food Prices and Inflation Expectations in New Zealand

Agribusiness, EarlyView.
ABSTRACT Food prices are conspicuous, and spending on food constitutes a considerable share of household expenditure. In this study, we use partially identified Bayesian structural vector autoregression models to analyze the effects of food price shocks on core inflation and 1‐ and 5‐year inflation expectations in New Zealand.
Puneet Vatsa, Gabriel Pino, Alex Acheampong   +2 more
wiley   +1 more source

Default Risk and Equity Returns: A Comparison of the Bank-Based German and the U.S. Financial System [PDF]

, 2009
In this paper, we address the question whether the impact of default risk on equity returns depends on the financial system firms operate in. Using an implementation of Merton's option-pricing model for the value of equity to estimate firms' default risk,
Andreas Schrimpf, Andrei Shleifer, Andrew Zhang, Arnoud W A Boot, Christoph M. Breig, Craig H Furfine, Dan Galai, David J Denis, Edward I Altman, Eli Ofek, Eugene Fama, Eugene Fama, Fischer Black, Glenn N Pettengill, Ilia D Dichev, James Ohlson, John H Cochrane, John H Cochrane, John M Griffin, Lars Hansen, Lorenzo Garlappi, Maria Vassalou, Michael F Ferguson, Murillo Campello, Murray Carlson, Ozgur Ince, Peter J Crosbie, Ralf Elsas, Ralf Elsas, Ralf Elsas, Robert C Merton, Stephen A Ross, Tim Loughran, Whitney K Newey   +33 more
core   +2 more sources

Primary Tumor Resection in Patients With Unresectable Metastatic Colorectal Cancer: A Systematic Review and Meta‐Analysis

Annals of Gastroenterological Surgery, EarlyView.
This systematic review and meta‐analysis evaluated the role of primary tumor resection (PTR) in asymptomatic patients with unresectable metastatic colorectal cancer. Across 17 eligible studies including 9317 patients, PTR did not improve overall or progression‐free survival compared with chemotherapy alone.
Junpei Takashima, Hirotoshi Kobayashi, Daisuke Fujimoto, Fumihiko Miura   +3 more
wiley   +1 more source

Effectiveness and acceptability of methods of communicating the results of clinical research to lay and professional audiences: protocol for a systematic review

Systematic Reviews, 2019
Background Phase III randomised controlled trials aim not just to increase the sum of human knowledge, but also to improve treatment, care or prevention for future patients through changing policy and practice.
Annabelle South, Julia Bailey, Mahesh K. B. Parmar, Claire L. Vale   +3 more
doaj   +1 more source