Results 31 to 40 of about 347,347 (243)

Organ‐specific redox imbalances in spinal muscular atrophy mice are partially rescued by SMN antisense oligonucleotides

open access: yesFEBS Letters, EarlyView.
We identified a systemic, progressive loss of protein S‐glutathionylation—detected by nonreducing western blotting—alongside dysregulation of glutathione‐cycle enzymes in both neuronal and peripheral tissues of Taiwanese SMA mice. These alterations were partially rescued by SMN antisense oligonucleotide therapy, revealing persistent redox imbalance as ...
Sofia Vrettou, Brunhilde Wirth
wiley   +1 more source

Transferrin receptor 1‐mediated iron uptake supports thermogenic activation in human cervical‐derived adipocytes

open access: yesFEBS Letters, EarlyView.
In this study, we found that human cervical‐derived adipocytes maintain intracellular iron level by regulating the expression of iron transport‐related proteins during adrenergic stimulation. Melanotransferrin is predicted to interact with transferrin receptor 1 based on in silico analysis.
Rahaf Alrifai   +9 more
wiley   +1 more source

Leishman-Giemsa Cocktail - Is it an Effective Stain for Air Dried Cytology Smears [PDF]

open access: yesJournal of Clinical and Diagnostic Research, 2017
Introduction: Air dried cytology smears are stained routinely with Romanowsky stains so that the relative cell size, nuclear size, cytoplasmic details, smear background elements and intercellular matrix components are better appreciated. A variety of
Shilpa Manigatta Doddagowda   +2 more
doaj   +1 more source

Influence of different types of noise on sentence recognition in normally hearing adults

open access: yesRevista CEFAC, 2021
Objective: to analyze speech perception in normally hearing adults when listening in silence and with different types of noise. Methods: 40 individuals of both sexes, aged 18 to 45 years, participated in the study.
Matheus Carvalho Ferreira   +3 more
doaj   +2 more sources

The planar cell polarity protein Vangl2 interacts with the PDZ‐domains of Scribble but not with a unique PDZ‐like domain in Inturned

open access: yesFEBS Letters, EarlyView.
Structural and biochemical characterisations show that the planar cell polarity (PCP) protein Inturned harbours a unique PDZ‐like domain that does not bind canonical PDZ‐binding motifs (PBMs) like that of another PCP protein Vangl2. In contrast, the apical‐basal polarity protein Scribble contains four PDZ domains that bind Vangl2, but one PDZ domain ...
Stephan Wilmes   +4 more
wiley   +1 more source

Optimization of a fruit juice cocktail containing soursop, pineapple, orange and mango using mixture design

open access: yesScientific African, 2020
A simplex lattice mixture design was used to optimize the formulation of a juice cocktail containing soursop, pineapple, mango and orange, based on physicochemical and sensory attributes of the cocktail.
Paa Toah Akonor
doaj   +1 more source

Supplementation of enzyme cocktail in chickens diet is an effective approach to increase the utilization of nutrient in wheat-based diets

open access: yesJournal of Animal Science and Technology, 2021
This experiment was conducted to evaluate the effect of supplementing enzyme cocktail on growth performance, digestibility of nutrients, and monosaccharide concentration in ileum and ceca of broiler chickens fed ...
Hanseo Ko   +4 more
doaj   +1 more source

Tau acetylation at K331 has limited impact on tau pathology in vivo

open access: yesFEBS Letters, EarlyView.
We mapped tau post‐translational modifications in humanized MAPT knock‐in mice and in amyloid‐bearing double knock‐in mice. Acetylation within the repeat domain, particularly around K331, showed modest increases under amyloid pathology. To test functional relevance, we generated MAPTK331Q knock‐in mice.
Shoko Hashimoto   +3 more
wiley   +1 more source

Cytoplasmic p21 promotes stemness of colon cancer cells via activation of the NFκB pathway

open access: yesMolecular Oncology, EarlyView.
Cytoplasmic p21 promotes colorectal cancer stem cell (CSC) features by destabilizing the NFκB–IκB complex, activating NFκB signaling, and upregulating BCL‐xL and COX2. In contrast to nuclear p21, cytoplasmic p21 enhances spheroid formation and stemness transcription factor CD133.
Arnatchai Maiuthed   +10 more
wiley   +1 more source

Produksi Nata de Whey: Solusi Penanganan Limbah Keju dari PT. Mazaraat Lokanatura Indonesia dan Pemberdayaan Masyarakat

open access: yesPrima: Journal of Community Empowering and Services
Nata de Whey Production: Solutions for Handling Cheese Waste from PT. Mazaraat Lokanatura Indonesia and Community Empowerment. One of the problems faced by PT Mazaraat Lokanatura Indonesia is the abundant liquid cheese waste (whey).
Siti Lusi Arum Sari   +5 more
doaj   +1 more source

Home - About - Disclaimer - Privacy