Results 141 to 150 of about 195,547 (311)
Molecular Oncology, EarlyView.Loss of the miR‐214/199a cluster is associated with recurrence in ovarian cancer. Engineered small extracellular vesicles (m214‐sEVs) elevate miR‐214‐3p/miR‐199a‐5p in tumor cells, suppress β‐catenin, TLR4, and YKT6 signaling, reprogram tumor‐derived sEV cargo, reduce chemoresistance and migration, and enhance carboplatin efficacy and survival in ...
Weida Wang +12 more
wiley +1 more source
, 1988 cod 2 nMost fishermen also used nets with meshes of five to six inches. These were leaded at intervals along the foot ropes, while cork floats..supported and kept the net fully extended when anchored to the bottom of the fishing grounds.
core
, 1989 cod 2 n[His] cod farm has been in operation for three years and has a total of 24 holding cages. Located in the inner, sheltered portion of Bay Bulls harbor, the cages are constructed of 1.75 inch mackerel mest (h?)[check] or netting with four ...
core +1 more source
Interrogating the immune landscape of microsatellite stable RAS‐mutated colon cancer
Molecular Oncology, EarlyView.COLOSSUS project RAS‐mutated MSS colon cancer study explored transcriptomics and immune cell density by immunohistochemistry (IHC), Immunoscore (IS), ISIC/TuLIS scores, mutation counts, and detected different prevalences but similar microenvironment composition across immune markers with clinical relevance for future immunotherapy combination ...
Rodrigo Dienstmann +61 more
wiley +1 more source
cod 2 nUsed I and SupUsed I3Not Usedcodd,codde,cod-fish,FISH n,BANK,RED,ROCK,SHORE1,TOM COD,as cold as a cod's nose,codfish is cod by name and by nature,no cod, no cash,cod-bag/blubber/fish/fishery/fishing/fish weather/flake/hauler/jigger/jigging/line ...
core
Molecular Oncology, EarlyView.Cytarabine is a key therapy for acute myeloid leukaemia (AML), but its efficacy is limited by the dNTPase SAMHD1, which hydrolyses its active metabolite. Screening nucleotide biosynthesis inhibitors revealed that IMPDH inhibitors selectively sensitise SAMHD1‐proficient AML cells to cytarabine.
Miriam Yagüe‐Capilla +9 more
wiley +1 more source
Molecular Oncology, EarlyView.Keratin 19 (KRT19) is overexpressed in high‐grade serous ovarian cancer with high levels of Kallikrein‐related peptidases (KLK) 4–7 and is associated with poor survival. In vivo analyses demonstrate that elevated KRT19 increases peritoneal tumour burden.
Sophia Bielesch +13 more
wiley +1 more source
, 1965 cod 2 nI sold fish for 1 1/2¢ a pound, cod net fish, Do you all use cod nets? Well this year nylon nets.DNE-cit W. J. KIRWINNOV 17 1965Used I and SupUsed I and Sup3Not Usedcodd,codde,cod-fish,FISH n,BANK,RED,ROCK,SHORE1,TOM COD,as cold as a cod's ...
core
Somatic mutational landscape in von Hippel–Lindau familial hemangioblastoma
Molecular Oncology, EarlyView.The causes of central nervous system (CNS) hemangioblastoma in Von Hippel–Lindau (vHL) disease are unclear. We used Whole Exome Sequencing (WES) on familial hemangioblastoma to investigate events that underlie tumor development. Our findings suggest that VHL loss creates a permissive environment for tumor formation, while additional alterations ...
Maja Dembic +5 more
wiley +1 more source