Results 241 to 250 of about 100,837 (319)
Cytarabine is a key therapy for acute myeloid leukaemia (AML), but its efficacy is limited by the dNTPase SAMHD1, which hydrolyses its active metabolite. Screening nucleotide biosynthesis inhibitors revealed that IMPDH inhibitors selectively sensitise SAMHD1‐proficient AML cells to cytarabine.
Miriam Yagüe‐Capilla +9 more
wiley +1 more source
Assessing the feasibility and appropriateness of verbal autopsy using contact information of the deceased from burial records in urban Bangladesh. [PDF]
Hossain AT +22 more
europepmc +1 more source
Keratin 19 (KRT19) is overexpressed in high‐grade serous ovarian cancer with high levels of Kallikrein‐related peptidases (KLK) 4–7 and is associated with poor survival. In vivo analyses demonstrate that elevated KRT19 increases peritoneal tumour burden.
Sophia Bielesch +13 more
wiley +1 more source
Adaptive modelling approach for predicting causes of death: insights from verbal autopsy data in Tanzania. [PDF]
Tunga M, Chambua J, Lungo J.
europepmc +1 more source
Somatic mutational landscape in von Hippel–Lindau familial hemangioblastoma
The causes of central nervous system (CNS) hemangioblastoma in Von Hippel–Lindau (vHL) disease are unclear. We used Whole Exome Sequencing (WES) on familial hemangioblastoma to investigate events that underlie tumor development. Our findings suggest that VHL loss creates a permissive environment for tumor formation, while additional alterations ...
Maja Dembic +5 more
wiley +1 more source
Lower-limb strength and power characteristics in relation to 180° change of direction ability in elite female basketball players. [PDF]
Ogata H +4 more
europepmc +1 more source
Correction: Oil droplet fouling and differential toxicokinetics of polycyclic aromatic hydrocarbons in embryos of Atlantic haddock and cod. [PDF]
Sørensen L +7 more
europepmc +1 more source
Schacktavelslek och intertextuell dialog i AM 191 fol. och Cod. Holm. D 3
Massimiliano Bampi
openalex +1 more source

