Results 91 to 100 of about 19,870 (237)
Phosphoinositides and inositol phosphates as molecular glues
FEBS Letters, EarlyView.Inositol phosphates (IPs) and phosphoinositides (PIPs) regulate diverse eukaryotic processes. Beyond recruiting signaling proteins or acting as structural cofactors, recent studies suggest they mediate protein–protein interactions as natural molecular glues.
Aleshia Seaton‐Terry +9 more
wiley +1 more source
The role of miR‐335‐5p in the redifferentiation of BRAF p.V600E thyroid cancers
Molecular Oncology, EarlyView.The BRAF p.V600E mutation promotes thyroid cancer dedifferentiation and radioiodine resistance. Using a network approach, we identified miR‐335‐5p as a key regulator of BRAF‐mutated thyroid tumors. Restoring miR‐335‐5p increased thyroid‐specific gene expression and iodine uptake in cells and organoids.
Valeria Pecce +11 more
wiley +1 more source
Identity-Based Cryptography: Feasibility & Applications in Next Generation Sensor Networks
, 2007 Elliptic Curve Cryptography (ECC) has been a very interesting research field for many applications, especially in sensor networks. The main reason for this is the restrictions on resources posed by sensor motes. ECC alleviates these restrictions by using
Kampanakis, Panagiotis T.
core
Molecular Oncology, EarlyView.Aptamers are used both therapeutically and as targeting agents in cancer treatment. We developed an aptamer‐targeted PLGA–TRAIL nanosystem that exhibited superior therapeutic efficacy in NOD/SCID breast cancer models. This nanosystem represents a novel biotechnological drug candidate for suppressing resistance development in breast cancer.
Gulen Melike Demirbolat +8 more
wiley +1 more source
Lossy Cryptography from Code-Based Assumptions
Over the past few decades, we have seen a proliferation of advanced cryptographic primitives with lossy or homomorphic properties built from various assumptions such as Quadratic Residuosity, Decisional Diffie-Hellman, and Learning with Errors. These primitives imply hard problems in the complexity class $SZK$ (statistical zero-knowledge); as a ...
Quang Dao, Aayush Jain
openaire +3 more sources
Molecular Oncology, EarlyView.In this explorative study, the abundance of circular RNA molecules in bone marrow stem cells was found to be elevated in patients with high‐risk myelodysplastic neoplasms, and to be associated with an increased risk of progression to acute myeloid leukemia.
Eileen Wedge +17 more
wiley +1 more source
Tensor-based trapdoors for CVP and their application to public key cryptography
, 1999 We propose two trapdoors for the Closest-Vector-Problem in lattices (CVP) related to the lattice tensor product.
Jean-Pierre Seifert +3 more
core +1 more source
Subtype‐specific enhancer RNAs define transcriptional regulators and prognosis in breast cancers
Molecular Oncology, EarlyView.This study employed machine learning methodologies to perform the subtype‐specific classification of RNA‐seq data sets, which are mapped on enhancers from TCGA‐derived breast cancer patients. Their integration with gene expression (referred to as ProxCReAM eRNAs) and chromatin accessibility profiles has the potential to identify lineage‐specific and ...
Aamena Y. Patel +6 more
wiley +1 more source
Introduction to code-based post-quantum cryptography
, 2020 This document serves as an introduction to code-based post-quantum cryptography for readers with no prior knowledge of cryptography or coding theory. The first chapter contains an introduction to cryptography from classical to post-quantum.
Saldarriaga Pérez, Juan Carlos
core
Molecular Oncology, EarlyView.Tumors contain diverse cellular states whose behavior is shaped by context‐dependent gene coordination. By comparing gene–gene relationships across biological contexts, we identify adaptive transcriptional modules that reorganize into distinct vulnerability axes.
Brian Nelson +9 more
wiley +1 more source