Results 91 to 100 of about 23,280,321 (280)
Golgi enzymes are retrieved from the plasma membrane to the trans‐Golgi network
FEBS Letters, EarlyView.Golgi enzymes are traditionally considered resident proteins retained within the Golgi apparatus. Here, we demonstrate that a subset transiently reaches the cell surface and is subsequently retrieved to the trans‐Golgi network via retrograde transport. Using a nanobody‐based toolkit, we uncover a dynamic trafficking cycle of several Golgi enzymes.
Dominik P. Buser, Tina Junne
wiley +1 more source
Ligand‐dependent transcriptional heterogeneity in cell cycle gene expression delays G1/S entry
FEBS Letters, EarlyView.EGF and HRG induce distinct G1/S progression programs in ErbB2‐amplified BT474 breast cancer cells. Despite activating the potent ErbB2–ErbB3 heterodimer, HRG does not accelerate cell‐cycle entry. Instead, EGF promotes earlier restriction‐point passage via ERK–FOS signaling, whereas HRG activates the AKT–MYC axis, driving transcriptional heterogeneity ...
Ririn Rahmala Febri +5 more
wiley +1 more source
Identity-Based Cryptography: Feasibility & Applications in Next Generation Sensor Networks
, 2007 Elliptic Curve Cryptography (ECC) has been a very interesting research field for many applications, especially in sensor networks. The main reason for this is the restrictions on resources posed by sensor motes. ECC alleviates these restrictions by using
Kampanakis, Panagiotis T.
core
Emerging experimental and computational methods for studying redox‐regulated structural transitions
FEBS Letters, EarlyView.Redox reactions can reshape proteins and alter how they behave in cells, with important consequences for health and disease. This review explores emerging experimental and computational approaches for discovering these redox‐sensitive protein switches, revealing their structural effects, and predicting their behavior, opening new opportunities to ...
Tasneem Rass +2 more
wiley +1 more source
New Developments in Quasigroup-Based Cryptography
, 2014 This chapter offers an overview of new developments in quasigroup-based cryptography, especially of new defined quasigroup-based block ciphers and stream ciphers, hash functions and message authentication codes, PRNGs, public key cryptosystems, etc ...
Mileva, Aleksandra
core +2 more sources
Lossy Cryptography from Code-Based Assumptions
Over the past few decades, we have seen a proliferation of advanced cryptographic primitives with lossy or homomorphic properties built from various assumptions such as Quadratic Residuosity, Decisional Diffie-Hellman, and Learning with Errors. These primitives imply hard problems in the complexity class $SZK$ (statistical zero-knowledge); as a ...
Quang Dao, Aayush Jain
openaire +3 more sources
Translophagy—A potential link between autophagy impairment and translational errors
FEBS Letters, EarlyView.Neurodegenerative diseases are characterised by the accumulation of abnormal proteins and protein aggregates, but their origin often remains unknown. We propose that selective autophagy removes damaged protein‐making machinery, preventing errors during protein synthesis.
Mykola V. Korolchuk +11 more
wiley +1 more source
FEBS Letters, EarlyView.Mycobacterial 3‐methylcrotonyl‐CoA carboxylase uses a mobile biotin‐carrying domain to shuttle a carboxyl group between two catalytic sites, enabling carboxylation of 3‐methylcrotonyl‐CoA during leucine breakdown. Cryo‐electron microscopy captures the carrier at both sites and reveals an inward loop movement that may prevent futile rebinding to the ...
Ajit Yadav +2 more
wiley +1 more source
FEBS Letters, EarlyView.How do genomes gain new functional parts? In eukaryotes, which tend to evolve under weak selection, much of the genome is junk. Palazzo and Qiu borrow the logic of Markov chains to show how non‐functional DNA becomes functional through the appearance of intermediate states, which arise due to epistasis, buffering, and biochemical messiness, allowing ...
Alexander F. Palazzo, Yi Qiu
wiley +1 more source
Code-based cryptography : new privacy-preserving constructions
, 2020 Code-based cryptography is one of the promising candidates of post-quantum cryptography. It has a long history, dated back to the seminal work by McEliece in 1978, but did suffer from a relatively slow development.
Zeng, Neng
core +1 more source