Results 61 to 70 of about 2,113,123 (295)

Degradation mechanism of the von Willebrand factor A2 domain by nattokinase

open access: yesFEBS Letters, EarlyView.
Nattokinase, a natto‐derived protease, exhibits potent antithrombotic effects. This study demonstrates that nattokinase directly cleaves the von Willebrand factor (vWF) A2 domain in vitro. Unlike the native regulator ADAMTS13, nattokinase degrades folded vWF independently of shear stress.
Ryuichi Hyakumoto   +3 more
wiley   +1 more source

Code Switching and Code Mixing Study in “Hitam Putih” Talk Show Program

open access: yesVivid: Journal of Language and Literature, 2021
This research aimed to investigate the kinds of code-switching and code-mixing used by the participants in Hitam Putih talk show. By analysing each statement of code-switching and code mixing which is spoken by the speakers of Hitam Putih talk show, the ...
Ayu Wulandari
doaj   +1 more source

Harmonizing Code-mixed Conversations: Personality-assisted Code-mixed Response Generation in Dialogues

open access: yesFindings of the Association for Computational Linguistics: EACL 2024
14 pages, 8 figures, 7 tables.
Shivani Kumar, Tanmoy Chakraborty 0002
openaire   +3 more sources

Design and analysis strategies for robust microbiome ageing research

open access: yesFEBS Letters, EarlyView.
The gut microbiome changes with age and associates with age‐related morbidity and mortality, establishing it as a potential biomarker and intervention target for ageing. Realising this potential requires methodological rigour, yet distinguishing biological signals from methodological artefacts remains challenging across cohorts. This review provides an
Mark Olenik   +5 more
wiley   +1 more source

CODE SWITCHING AND CODE MIXING IN BILINGUAL CLASSROOM INTERACTION [PDF]

open access: yes, 2023
There are several international schools or even semi-international schools that utilize foreign language, especially the youth who has mastered their mother tongue sometimes (if not often) do code switch and/or code mix language to English alternately or
Syam, Andi Tenrisanna
core   +1 more source

AN ANALYSIS OF CODE MIXING IN A DEBATE ACTIVITY AS PART OF ENGLISH CLUB PROGRAMS AT SMAN 2 BENGKULU CITY

open access: yesJournal of English Education and Teaching, 2018
The aim of this research is to investigate code mixing produced by the students of ‘Debate Activity as part of English Club’ program at SMAN 2 Bengkulu city. The design are descriptive quantitative and qualitative.
Darpeli Eli Zetri   +2 more
doaj   +1 more source

An epithelial GPR35 isoform supports tumor‐associated transcriptional and metabolic phenotypes

open access: yesFEBS Letters, EarlyView.
GPR35 generates two functionally distinct isoforms with previously unresolved roles. GPR35‐short mediates immune‐cell chemotaxis, while GPR35‐long is enriched in colorectal cancer epithelium, where it supports increased metabolism, proliferation, and tumor‐associated transcriptional programs.
Jørgen D. Rønneberg   +14 more
wiley   +1 more source

Peripheral lysosomes recruit PLEKHG3 to focal adhesions and restrain protrusion dynamics

open access: yesFEBS Letters, EarlyView.
Proximity‐dependent labeling at the LAMTOR complex revealed the Rho GEF PLEKHG3 as a lysosome‐proximal protein directing the study toward the influence of lysosome positioning on actin dynamics and cell motility. We show that PLEKHG3 colocalizes with lysosomes at focal adhesion sites and observe that forced peripheral dispersion of lysosomes hinders ...
Rainer Ettelt   +8 more
wiley   +1 more source

Engineering peptides into antibodies—opportunities and strategies for therapeutic innovation

open access: yesFEBS Letters, EarlyView.
Peptides and antibodies occupy complementary therapeutic niches. Peptides recognize difficult targets in a compact format, while antibodies add specificity, long half‐life, and effector functions. This review examines strategies that merge both modalities—peptide grafting into loops, terminal and Fc fusions, and bioconjugation—highlighting how ...
Jinling Wang   +2 more
wiley   +1 more source

International Building Code: 2009 [PDF]

open access: yes, 2009
Manual describing best practices for constructing buildings that meet safety and energy requirements; appropriate building materials and use; and related issues: "This comprehensive building code establishes minimum regulations for building systems using
International Code Council
core  

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