Results 81 to 90 of about 1,423,399 (288)

Hyperosmotic stress‐induced redistribution of pre‐mRNA cleavage factor I subunits is associated with shifts in alternative polyadenylation

open access: yesFEBS Open Bio, EarlyView.
Hyperosmotic stress triggers the relocation of the CFIm complex from the nucleus to the cytoplasm. This shift creates a nuclear ‘stoichiometric bottleneck’, limiting CFIm availability for mRNA processing. Consequently, specific mRNAs like NUDT21 and DICER1 undergo targeted 3′UTR shortening, demonstrating how spatial protein dynamics drive rapid ...
Hitomi Soumiya   +2 more
wiley   +1 more source

Code Switching Types Used by Lecturers

open access: yes, 2018
It became one phenomenon occurred when lecturer changed one language (L1) into other language (L2) in one utterance. This was one kind of bilingualism named code switching.
J, Syilvia Wenny
core   +1 more source

MagmaFlow: A desktop platform for artificial intelligence‐driven expression analysis

open access: yesFEBS Open Bio, EarlyView.
MagmaFlow is a free, no‐code platform for gene expression analysis. It generates interactive volcano plots, links genes to literature, pathways, and diseases, prioritizes candidates using millions of publications, identifies affected biological processes, builds network diagrams, and exports publication‐ready figures and reports for macOS and Windows ...
Carlos E. Buss   +7 more
wiley   +1 more source

A Depolarizing Leak in Sodium Bicarbonate Cotransporter NBCe1 Causes Brain Edema

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objectives SLC4A4 encodes electrogenic sodium bicarbonate cotransporter NBCe1, prominently expressed in kidney and brain. Recessive loss‐of‐function variants in SLC4A4 cause proximal renal tubular acidosis, no brain edema. In the brain, NBCe1 is expressed by astrocytes, where it regulates pH and mediates astrocyte volume changes.
Quinty Bisseling   +16 more
wiley   +1 more source

Teachers’ and students’ attitudes and practices regarding code switching in writing: A study in selected primary schools in St. Lucia.

open access: yes, 2011
This study was conducted in three primary schools in St. Lucia, a multilingual country situated in the Caribbean. The goal of this research was to investigate teachers’ and students’ attitudes and practices regarding the use of code switching in the ...
Auguste-Walter, Berthina
core  

Elusive or self-evident? Looking for common ground in approaches to code-switching

open access: yes, 2015
The study of code-switching has been tackled by three distinct strands of research, namely linguistic, psycholinguistic and sociolinguistic. The linguistic strand has been concerned with the search for universal grammatical constraints to code-switching.
Stell, Gerald   +3 more
core   +1 more source

A Pedagogical Evaluation of Intra-Sentential Code-Switching Patterns in L2 Classroom Talk [PDF]

open access: yes, 2009
The paper is concerned with teachers' and students' alternation between L1 and L2 within the same utterance, i.e. uses of intra-sentential code-switching which in classroom discourse tends to be less accepted by modern language pedagogy than its inter ...
Jan Majer, Majer, Jan
core   +1 more source

The That-Trace Effect: Evidence from Spanish–English Code-Switching

open access: yes, 2021
The that-trace effect is the fact that many languages (like English) ban the extraction of embedded-clause subjects but not objects over an overt complementizer like that, while many other languages (like Spanish) allow such extractions.
Shane Ebert (10639046)   +1 more
core   +1 more source

Real‐World Longitudinal Data on the Impact of Hydroxychloroquine Blood Level Monitoring on Lupus Outcomes: Results of a Prospective Longitudinal Cohort Study

open access: yesArthritis Care &Research, EarlyView.
Objective Hydroxychloroquine (HCQ) is a cornerstone therapy in systemic lupus erythematosus (SLE), but the weight‐based dosing does not account for clinical factors that can introduce individual variability in drug metabolism and clearance. We leveraged longitudinal data from a prospective SLE cohort to identify clinical factors that predict ...
Jay J. Patel   +6 more
wiley   +1 more source

Code-Switching

open access: yes, 2015
Code-Switching ist ein Sprachstil, der sich durch das Mischen mehrerer Sprachen auszeichnet und wie jeder andere Sprachstil pragmatischen und syntaktischen Beschränkungen unterliegt. Während LinguistInnen Code-Switching als Indiz für einen hohen Beherrschungsgrad der Sprachen ansehen, wird das Sprachenmischen vom Laien als Kompetenzmangel wahrgenommen.
Anika Schmeißer   +8 more
openaire   +2 more sources

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