Results 101 to 110 of about 4,394,633 (291)

Nuanced Code Clone Detection Through LLM-Based Code Revision and AST Graph Modeling

open access: yesIEEE Access
Detecting semantically equivalent but syntactically diverse code clones (Type-4) remains challenging for traditional AST- or token-based approaches. We propose a clone detection framework that couples LLM-based code revision with AST graph modeling and ...
Chunguang Li   +3 more
doaj   +1 more source

USP29‐regulated noncanonical stabilization of the hypoxia‐inducible factor‐α in aggressive prostate cancer

open access: yesMolecular Oncology, EarlyView.
We identify USP29 as the only DUB mirroring CA9 expression, a marker of hypoxia and HIF pathway activation associated with PCA aggressiveness. USP29 stabilizes HIF‐1α and HIF‐2α via a noncanonical mechanism that is independent of PHD/pVHL activity yet relies on proteasomal regulation, establishing USP29 as a previously unrecognized regulator of hypoxic
Amelie S Schober   +16 more
wiley   +1 more source

Enhancing generic code clone detection model through protected access modifier rule and weightage [PDF]

open access: yes, 2016
Code clone is a common term used to refer codes that have been repeated multiple times in a program. There are four types of code clone which are type I, type II, type III and type IV.
Siti An Nasihah, Mohd Napi
core   +2 more sources

Finding novel vulnerabilities of hypomorphic BRCA1 alleles

open access: yesMolecular Oncology, EarlyView.
Synthetic lethality screens performed to identify novel vulnerabilities often model complete gene loss, thereby overlooking patient‐derived hypomorphic mutations. In this study, we have performed genome‐wide CRISPR screens on BRCA1 hypomorphic mutations, showing BRCA1I26A behaves like wild‐type, while BRCA1R1699Q mimics deficiency. Furthermore, we have
Anne Schreuder   +10 more
wiley   +1 more source

A novel quinazolinone insulin receptor inhibitor and its synergy with an EGFR inhibitor in glucose‐driven glioblastoma

open access: yesMolecular Oncology, EarlyView.
The novel styrylquinazolinone‐based molecule W1B effectively suppresses glioblastoma by inhibiting IGF1R and EGFR. In high‐glucose microenvironments driving tumor resistance, W1B acts synergistically with the EGFR inhibitor dacomitinib. This combination safely blocks compensatory survival signaling in zebrafish xenograft models. Showcasing promising in
Patryk Rurka   +9 more
wiley   +1 more source

Detecting Java Code Clones Based on Bytecode Sequence Alignment

open access: yesIEEE Access, 2019
When the source code is copied and pasted or modified, there will be a lot of identical or similar code snippets in the software system, which are called code clones.
Dongjin Yu   +3 more
doaj   +1 more source

Loss of proton‐sensing TDAG8 increases tumor progression in mouse models of colon cancer

open access: yesMolecular Oncology, EarlyView.
Loss of the pH‐sensing receptor TDAG8 accelerates colorectal cancer progression in mice. Animals lacking TDAG8 expression had increased tumor growth, DNA damage, and recruitment of tumor‐associated immune cells, including macrophages, neutrophils, and monocytes.
Ermanno Malagola   +11 more
wiley   +1 more source

Code Clone Detection Using Wavelets [PDF]

open access: yes, 2014
For different reasons, developers may produce code that is cloned. It has a negative impact on code quality and code clones are one of the most frequent problems that may appear in a software project.
Kilgi, Karl
core  

AN APPROACH FOR CLONE DETECTION IN DOCUMENTATION REUSE [PDF]

open access: yesНаучно-технический вестник информационных технологий, механики и оптики, 2014
The paper focuses on the searching method for repetitions in DocBook/DRL or plain text documents. An algorithm has been designed based on software clone detection. The algorithm supports filtering results: clones are rejected if clone length in the group
D. V. Lutsiv   +5 more
doaj  

PAK1 activation drives divergent resistance mechanisms to aromatase inhibition and tamoxifen in a luminal: A breast cancer model

open access: yesMolecular Oncology, EarlyView.
Breast cancer remains a major cause of cancer death in women, frequently developing endocrine therapy resistance. This study demonstrates that upregulated p21‐activated kinase 1 (PAK1) activity drives resistance to tamoxifen and long‐term estrogen deprivation in ER+ breast cancer models.
Luisa Schwarzmüller   +10 more
wiley   +1 more source

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