Results 81 to 90 of about 4,394,633 (291)

Scalable code clone detection tool based on semantic analysis

open access: yesТруды Института системного программирования РАН, 2018
This article describes the methods of code clones detection. New approach of code clones detection is proposed for C/C++ languages based on analysis of existed methods.
Sevak Sargsyan   +4 more
doaj   +1 more source

Ligand‐dependent transcriptional heterogeneity in cell cycle gene expression delays G1/S entry

open access: yesFEBS Letters, EarlyView.
EGF and HRG induce distinct G1/S progression programs in ErbB2‐amplified BT474 breast cancer cells. Despite activating the potent ErbB2–ErbB3 heterodimer, HRG does not accelerate cell‐cycle entry. Instead, EGF promotes earlier restriction‐point passage via ERK–FOS signaling, whereas HRG activates the AKT–MYC axis, driving transcriptional heterogeneity ...
Ririn Rahmala Febri   +5 more
wiley   +1 more source

Code Clones: Detection and Management

open access: yesProcedia Computer Science, 2018
Abstract In a software system, similar or identical fragments of code are known as code clones. Instead of implementing a new code from scratch, most of the developers prefer copy–paste programming in which they use existing code fragments. So, the primary reason behind code cloning isboth developers and programming languages used by them.
Neha Saini, Sukhdip Singh, null Suman
openaire   +1 more source

Emerging experimental and computational methods for studying redox‐regulated structural transitions

open access: yesFEBS Letters, EarlyView.
Redox reactions can reshape proteins and alter how they behave in cells, with important consequences for health and disease. This review explores emerging experimental and computational approaches for discovering these redox‐sensitive protein switches, revealing their structural effects, and predicting their behavior, opening new opportunities to ...
Tasneem Rass   +2 more
wiley   +1 more source

Platform-independent and scalable tool for binary code clone detection

open access: yesТруды Института системного программирования РАН, 2018
During the software development developers often copy and paste fragments of code to achieve the desired result. Copying of code can lead to variety of errors, as well as can increase the size of the source and binary code.
H. K. Aslanyan   +4 more
doaj   +1 more source

Structural and biochemical analysis of a B12 superbinder

open access: yesFEBS Letters, EarlyView.
BtuG proteins are vitamin B12 scavengers in Bacteroides thetaiotaomicron, a dominant human gut bacterium. We present crystal structures of three BtuG homologs bound to cobalamin and its precursor cobinamide, revealing picomolar binding affinities, among the highest known for any natural protein.
Jose M. Martinez Felices   +3 more
wiley   +1 more source

Structures of mycobacterial 3‐methylcrotonyl‐CoA carboxylase reveal carrier‐domain translocation between catalytic sites

open access: yesFEBS Letters, EarlyView.
Mycobacterial 3‐methylcrotonyl‐CoA carboxylase uses a mobile biotin‐carrying domain to shuttle a carboxyl group between two catalytic sites, enabling carboxylation of 3‐methylcrotonyl‐CoA during leucine breakdown. Cryo‐electron microscopy captures the carrier at both sites and reveals an inward loop movement that may prevent futile rebinding to the ...
Ajit Yadav   +2 more
wiley   +1 more source

A Novel Method for Code Clone Detection Based on Minimally Random Kernel Convolutional Transform

open access: yesIEEE Access
Effectively detecting code clones is essential for maintaining and evolving software systems. This paper introduces a novel approach that leverages minimally random kernel convolutional transform (MiniRocket) to represent source code for clone detection.
Mostefai Abdelkader
doaj   +1 more source

The Shewanella oneidensis Fic enzyme SoFic targets the switch‐I region of EF‐Tu for AMPylation

open access: yesFEBS Letters, EarlyView.
Fic enzymes mediate diverse post‐translational modifications across all domains of life, including AMPylation. Prokaryotic EF‐Tu can be AMPylated and deAMPylated by the conserved Fic enzyme SoFic. Structural and biochemical approaches were used to characterize the effect of AMPylation on EF‐Tu, SoFic's enzymatic activities, and the enzyme‐target ...
Svenja Runge   +6 more
wiley   +1 more source

LeONet: A Hybrid Deep Learning Approach for High-Precision Code Clone Detection Using Abstract Syntax Tree Features

open access: yesBig Data and Cognitive Computing
Code duplication, commonly referred to as code cloning, is not inherent in software systems but arises due to various factors, such as time constraints in meeting project deadlines.
Thanoshan Vijayanandan   +4 more
doaj   +1 more source

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