Results 81 to 90 of about 240,865 (343)

Comparing Assembler Procedures by Analyzing Sequences of Opcodes

open access: yesTelfor Journal, 2020
Static analysis of executables for the purpose of comparing them can be made more difficult if the binaries are created using different compilers. In order to compensate for the noise introduced by the compilers, the arguments of the instructions are ...
N. Pejić   +2 more
doaj   +1 more source

Liquid biopsy epigenetics: establishing a molecular profile based on cell‐free DNA

open access: yesMolecular Oncology, EarlyView.
Cell‐free DNA (cfDNA) fragments in plasma from cancer patients carry epigenetic signatures reflecting their cells of origin. These epigenetic features include DNA methylation, nucleosome modifications, and variations in fragmentation. This review describes the biological properties of each feature and explores optimal strategies for harnessing cfDNA ...
Christoffer Trier Maansson   +2 more
wiley   +1 more source

Intein‐based modular chimeric antigen receptor platform for specific CD19/CD20 co‐targeting

open access: yesMolecular Oncology, EarlyView.
CARtein is a modular CAR platform that uses split inteins to splice antigen‐recognition modules onto a universal signaling backbone, enabling precise, scarless assembly without re‐engineering signaling domains. Deployed here against CD19 and CD20 in B‐cell malignancies, the design supports flexible multi‐antigen targeting to boost T‐cell activation and
Pablo Gonzalez‐Garcia   +9 more
wiley   +1 more source

Test-Based Clone Detection: an Initial Try on Semantically Equivalent Methods

open access: yesIEEE Access, 2018
Most code clone detection approaches identify clones via static source code analysis. Such approaches are effective and efficient in detecting lexically similar clones.
Guangjie Li   +3 more
doaj   +1 more source

Incremental Detection of Parameterized Code Clones [PDF]

open access: yesSoftwaretechnik-Trends, 2013
This paper presents a new approach to incremental code clone detection that is based on a special clone representation model. The algorithm detects parameterized clones with parameters of arbitrary size. It can be used for cross-system and cross-revision clone detection.
openaire   +1 more source

Improving PARP inhibitor efficacy in bladder cancer without genetic BRCAness by combination with PLX51107

open access: yesMolecular Oncology, EarlyView.
Clinical trials on PARP inhibitors in urothelial carcinoma (UC) showed limited efficacy and a lack of predictive biomarkers. We propose SLFN5, SLFN11, and OAS1 as UC‐specific response predictors. We suggest Talazoparib as the better PARP inhibitor for UC than Olaparib.
Jutta Schmitz   +15 more
wiley   +1 more source

Cytoplasmic p21 promotes stemness of colon cancer cells via activation of the NFκB pathway

open access: yesMolecular Oncology, EarlyView.
Cytoplasmic p21 promotes colorectal cancer stem cell (CSC) features by destabilizing the NFκB–IκB complex, activating NFκB signaling, and upregulating BCL‐xL and COX2. In contrast to nuclear p21, cytoplasmic p21 enhances spheroid formation and stemness transcription factor CD133.
Arnatchai Maiuthed   +10 more
wiley   +1 more source

MSSA: multi-stage semantic-aware neural network for binary code similarity detection [PDF]

open access: yesPeerJ Computer Science
Binary code similarity detection (BCSD) aims to identify whether a pair of binary code snippets is similar, which is widely used for tasks such as malware analysis, patch analysis, and clone detection.
Bangrui Wan   +4 more
doaj   +2 more sources

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