Results 61 to 70 of about 2,037,717 (291)
Protein pyrophosphorylation by inositol pyrophosphates — detection, function, and regulation
FEBS Letters, EarlyView.Protein pyrophosphorylation is an unusual signaling mechanism that was discovered two decades ago. It can be driven by inositol pyrophosphate messengers and influences various cellular processes. Herein, we summarize the research progress and challenges of this field, covering pathways found to be regulated by this posttranslational modification as ...
Sarah Lampe +3 more
wiley +1 more source
Building on the DEPLOY legacy: code generation and simulation
, 2012 The RODIN, and DEPLOY projects have laid solid foundations for further theoretical, and practical (methodological and tooling) advances with Event-B; we investigated code generation for embedded, multi-tasking systems. This work describes activities from
Butler, Michael +2 more
core +1 more source
Function‐driven design of a surrogate interleukin‐2 receptor ligand
FEBS Letters, EarlyView.Interleukin (IL)‐2 signaling can be achieved and precisely fine‐tuned through the affinity, distance, and orientation of the heterodimeric receptors with their ligands. We designed a biased IL‐2 surrogate ligand that selectively promotes effector T and natural killer cell activation and differentiation. Interleukin (IL) receptors play a pivotal role in
Ziwei Tang +9 more
wiley +1 more source
An Approach for Rapid Source Code Development Based on ChatGPT and Prompt Engineering
IEEE AccessCode generation stands as a powerful technique in modern software development, improving development efficiency, reducing errors, and fostering standardization and consistency.
Youjia Li, Jianjun Shi, Zheng Zhang
doaj +1 more source
Loo.py: transformation-based code generation for GPUs and CPUs
, 2014 Today's highly heterogeneous computing landscape places a burden on programmers wanting to achieve high performance on a reasonably broad cross-section of machines.
Asanovic K., Ellson J., Rubinsteyn A.
core +1 more source
Multiple ETS family transcription factors bind mutant p53 via distinct interaction regions
FEBS Letters, EarlyView.Mutant p53 gain‐of‐function is thought to be mediated by interaction with other transcription factors. We identify multiple ETS transcription factors that can bind mutant p53 and found that this interaction can be promoted by a PXXPP motif. ETS proteins that strongly bound mutant p53 were upregulated in ovarian cancer compared to ETS proteins that ...
Stephanie A. Metcalf +6 more
wiley +1 more source
Code Generation Untuk Object Relational Mapping Dengan Menggunakan LINQ Dan Text Templating [PDF]
, 2016 The increase towards Object Oriented Design creates a big gap between OO and relational database. In the other side, relational database still a big favor in designing business-powered application.
Rismanto, R. (Ridwan)
core
Automatic Generation of Text Descriptive Comments for Code Blocks
, 2018 We propose a framework to automatically generate descriptive comments for source code blocks. While this problem has been studied by many researchers previously, their methods are mostly based on fixed template and achieves poor results.
Liang, Yuding, Zhu, Kenny Q.
core +1 more source
The newfound relationship between extrachromosomal DNAs and excised signal circles
FEBS Letters, EarlyView.Extrachromosomal DNAs (ecDNAs) contribute to the progression of many human cancers. In addition, circular DNA by‐products of V(D)J recombination, excised signal circles (ESCs), have roles in cancer progression but have largely been overlooked. In this Review, we explore the roles of ecDNAs and ESCs in cancer development, and highlight why these ...
Dylan Casey, Zeqian Gao, Joan Boyes
wiley +1 more source
Particle-in-Cell simulations of electron spin effects in plasmas
, 2012 We have here developed a particle-in-cell code accounting for the magnetic dipole force and for the magnetization currents associated with the electron spin.
Brodin, G., Holkundkar, A., Marklund, M.
core +1 more source