Results 61 to 70 of about 2,043,855 (291)

From product codes to structured generalized LDPC codes [PDF]

open access: yesProceedings of the 5th International ICST Conference on Communications and Networking in China, 2010
Product codes, due to their relatively large minimum distance, are often seen as a natural solution for applications requiring low error floors. In this paper, we show by means of an ensemble weight enumerator analysis that the minimum distance multiplicities of product codes are much higher than those obtainable by other generalized LDPC (GLDPC ...
M. Lentmaier   +3 more
openaire   +5 more sources

Structural biology of ferritin nanocages

open access: yesFEBS Letters, EarlyView.
Ferritin is a conserved iron‐storage protein that sequesters iron as a ferric mineral core within a nanocage, protecting cells from oxidative damage and maintaining iron homeostasis. This review discusses ferritin biology, structure, and function, and highlights recent cryo‐EM studies revealing mechanisms of ferritinophagy, cellular iron uptake, and ...
Eloise Mastrangelo, Flavio Di Pisa
wiley   +1 more source

Tau acetylation at K331 has limited impact on tau pathology in vivo

open access: yesFEBS Letters, EarlyView.
We mapped tau post‐translational modifications in humanized MAPT knock‐in mice and in amyloid‐bearing double knock‐in mice. Acetylation within the repeat domain, particularly around K331, showed modest increases under amyloid pathology. To test functional relevance, we generated MAPTK331Q knock‐in mice.
Shoko Hashimoto   +3 more
wiley   +1 more source

Building on the DEPLOY legacy: code generation and simulation

open access: yes, 2012
The RODIN, and DEPLOY projects have laid solid foundations for further theoretical, and practical (methodological and tooling) advances with Event-B; we investigated code generation for embedded, multi-tasking systems. This work describes activities from
Butler, Michael   +2 more
core   +1 more source

Gut microbiome and aging—A dynamic interplay of microbes, metabolites, and the immune system

open access: yesFEBS Letters, EarlyView.
Age‐dependent shifts in microbial communities engender shifts in microbial metabolite profiles. These in turn drive shifts in barrier surface permeability of the gut and brain and induce immune activation. When paired with preexisting age‐related chronic inflammation this increases the risk of neuroinflammation and neurodegenerative diseases.
Aaron Mehl, Eran Blacher
wiley   +1 more source

Analysis of Intelligent Transportation Systems Using Model-Driven Simulations

open access: yesSensors, 2015
Intelligent Transportation Systems (ITSs) integrate information, sensor, control, and communication technologies to provide transport related services. Their users range from everyday commuters to policy makers and urban planners. Given the complexity of
Alberto Fernández-Isabel   +1 more
doaj   +1 more source

A methionine‐lined active site governs carbocation stabilization and product specificity in a bacterial terpene synthase

open access: yesFEBS Letters, EarlyView.
This study reveals a unique active site enriched in methionine residues and demonstrates that these residues play a critical role by stabilizing carbocation intermediates through novel sulfur–cation interactions. Structure‐guided mutagenesis further revealed variants with significantly altered product profiles, enhancing pseudopterosin formation. These
Marion Ringel   +13 more
wiley   +1 more source

Valosin‐containing protein counteracts ATP‐driven dissolution of FUS condensates through its ATPase activity in vitro

open access: yesFEBS Letters, EarlyView.
Biomolecular condensates formed by fused in sarcoma (FUS) are dissolved by high ATP concentrations yet persist in cells. Using a reconstituted system, we demonstrate that valosin‐containing protein (VCP), an AAA+ ATPase, counteracts ATP‐driven dissolution of FUS condensates through its D2 ATPase activity.
Hitomi Kimura   +2 more
wiley   +1 more source

Program Code Generation with Generative AIs

open access: yesAlgorithms
Our paper compares the correctness, efficiency, and maintainability of human-generated and AI-generated program code. For that, we analyzed the computational resources of AI- and human-generated program code using metrics such as time and space ...
Baskhad Idrisov, Tim Schlippe
doaj   +1 more source

Automatic Generation of Text Descriptive Comments for Code Blocks

open access: yes, 2018
We propose a framework to automatically generate descriptive comments for source code blocks. While this problem has been studied by many researchers previously, their methods are mostly based on fixed template and achieves poor results.
Liang, Yuding, Zhu, Kenny Q.
core   +1 more source

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