Results 81 to 90 of about 4,499,855 (300)
Code generation approaches for parallel geometric multigrid solvers
Analele Stiintifice ale Universitatii Ovidius Constanta: Seria Matematica, 2020 Software development for applications in computational science and engineering has become complex in recent years. This is mainly due to the increasing parallelism and heterogeneity in modern computer architectures and to the more realistic physical and ...
Köstler Harald +5 more
doaj +1 more source
Golgi enzymes are retrieved from the plasma membrane to the trans‐Golgi network
FEBS Letters, EarlyView.Golgi enzymes are traditionally considered resident proteins retained within the Golgi apparatus. Here, we demonstrate that a subset transiently reaches the cell surface and is subsequently retrieved to the trans‐Golgi network via retrograde transport. Using a nanobody‐based toolkit, we uncover a dynamic trafficking cycle of several Golgi enzymes.
Dominik P. Buser, Tina Junne
wiley +1 more source
Alaska Criminal Code Revision Subcommission [PDF]
, 1978 As of 1975, Alaska’s criminal laws were based primarily on Oregon criminal statutes as they existed at the close of the nineteenth century, with new statutes added and old statutes amended over the succeeding 75 years by Alaska territorial and state ...
Alaska Criminal Code Revision Subcommission
core
ISPRS International Journal of Geo-InformationGeospatial data provide an important basis for urban governance, resource management, disaster assessment, and public health analysis by linking spatial locations, attribute information, and dynamic processes.
Zhiyuan Le +6 more
doaj +1 more source
Anemic Domain Model vs Rich Domain Model to Improve the Two-Hemisphere Model-Driven Approach
Applied Computer Systems, 2020 Evolution of software development process and increasing complexity of software systems calls for developers to pay great attention to the evolution of CASE tools for software development.
Nikiforova Oksana, Gusarovs Konstantins
doaj +1 more source
Ligand‐dependent transcriptional heterogeneity in cell cycle gene expression delays G1/S entry
FEBS Letters, EarlyView.EGF and HRG induce distinct G1/S progression programs in ErbB2‐amplified BT474 breast cancer cells. Despite activating the potent ErbB2–ErbB3 heterodimer, HRG does not accelerate cell‐cycle entry. Instead, EGF promotes earlier restriction‐point passage via ERK–FOS signaling, whereas HRG activates the AKT–MYC axis, driving transcriptional heterogeneity ...
Ririn Rahmala Febri +5 more
wiley +1 more source
Algorithmic Bias and Logical Inconsistency in LLM-Generated Code
Big Data and Cognitive ComputingGenerative AI enables both software engineers and non-programmer domain experts to easily generate executable code. However, software engineers often lack domain-specific nuance to detect subtle AI logic errors, while domain experts typically lack the ...
Puspha Raj Pandeya, Igor Crk
doaj +1 more source
Emerging experimental and computational methods for studying redox‐regulated structural transitions
FEBS Letters, EarlyView.Redox reactions can reshape proteins and alter how they behave in cells, with important consequences for health and disease. This review explores emerging experimental and computational approaches for discovering these redox‐sensitive protein switches, revealing their structural effects, and predicting their behavior, opening new opportunities to ...
Tasneem Rass +2 more
wiley +1 more source
Translophagy—A potential link between autophagy impairment and translational errors
FEBS Letters, EarlyView.Neurodegenerative diseases are characterised by the accumulation of abnormal proteins and protein aggregates, but their origin often remains unknown. We propose that selective autophagy removes damaged protein‐making machinery, preventing errors during protein synthesis.
Mykola V. Korolchuk +11 more
wiley +1 more source
Code Generation for Niche Programming Languages with Large Language Models
Code generation is a prominent use-case for Large Language Models (LLMs). Specialized LLMs such as CodeLlama or Codestral are trained on a large variety of programming languages and achieve a strong performance on coding tasks.
Chen, Wei +2 more
core +1 more source