Results 101 to 110 of about 461,576 (313)

Circular RNA expression landscapes in myelodysplastic neoplasms: Associations with mutational signatures and disease progression

open access: yesMolecular Oncology, EarlyView.
In this explorative study, the abundance of circular RNA molecules in bone marrow stem cells was found to be elevated in patients with high‐risk myelodysplastic neoplasms, and to be associated with an increased risk of progression to acute myeloid leukemia.
Eileen Wedge   +17 more
wiley   +1 more source

Generation of all-optical Walsh–Hadamard code using silicon micro-ring resonator [PDF]

open access: yes
Silicon micro-ring resonator-based generation of all-optical ( 2 × 2 ) Walsh–Hadamard code is proposed. The energy-efficient, ultra-high-speed, and compact nature of micro-ring resonator-based devices is essential for optical computing.
Massoud, Yehia Mahmoud   +5 more
core   +1 more source

AUKE: Automatic Kernel Code Generation for an analogue SIMD Focal-plane Sensor-Processor Array [PDF]

open access: yes, 2018
Focal-plane Sensor-Processor Arrays (FPSPs) are new imaging devices with parallel Single Instruction Multiple Data (SIMD) computational capabilities built into every pixel.
Debrunner, Thomas   +2 more
core   +1 more source

Subtype‐specific enhancer RNAs define transcriptional regulators and prognosis in breast cancers

open access: yesMolecular Oncology, EarlyView.
This study employed machine learning methodologies to perform the subtype‐specific classification of RNA‐seq data sets, which are mapped on enhancers from TCGA‐derived breast cancer patients. Their integration with gene expression (referred to as ProxCReAM eRNAs) and chromatin accessibility profiles has the potential to identify lineage‐specific and ...
Aamena Y. Patel   +6 more
wiley   +1 more source

Network divergence analysis identifies adaptive gene modules and two orthogonal vulnerability axes in pancreatic cancer

open access: yesMolecular Oncology, EarlyView.
Tumors contain diverse cellular states whose behavior is shaped by context‐dependent gene coordination. By comparing gene–gene relationships across biological contexts, we identify adaptive transcriptional modules that reorganize into distinct vulnerability axes.
Brian Nelson   +9 more
wiley   +1 more source

Building on the DEPLOY legacy: code generation and simulation [PDF]

open access: yes, 2012
The RODIN, and DEPLOY projects have laid solid foundations for further theoretical, and practical (methodological and tooling) advances with Event-B; we investigated code generation for embedded, multi-tasking systems. This work describes activities from
Edmunds, Andrew   +2 more
core  

DOLFIN: Automated finite element computing [PDF]

open access: yes, 2009
We describe here a library aimed at automating the solution of partial differential equations using the finite element method. By employing novel techniques for automated code generation, the library combines a high level of expressiveness with efficient
Wells, G.N., Logg, Anders,, Logg, Anders
core   +2 more sources

Pre‐analytical optimization of cell‐free DNA and extracellular vesicle‐derived DNA for mutation detection in liquid biopsies

open access: yesMolecular Oncology, EarlyView.
Pre‐analytical handling critically determines liquid biopsy performance. This study defines practical best‐practice conditions for cell‐free DNA (cfDNA) and extracellular vesicle–derived DNA (evDNA), showing how processing time, storage conditions, tube type, and plasma input volume affect DNA integrity and mutation detection.
Jonas Dohmen   +11 more
wiley   +1 more source

Distribution Network Protection Considering Grid Code Requirements for Distributed Generation [PDF]

open access: yes, 2015
peer reviewedThe amount of inverter based distributed generation (DG) connected to the low and medium voltage levels is increasing rapidly. Their growing impact on the power system has already driven some distribution network operators to start imposing ...
Sachau, Juergen   +3 more
core   +1 more source

EDNRB‐dependent endothelin signaling reduces proliferation and promotes proneural‐to‐mesenchymal transition in gliomas

open access: yesMolecular Oncology, EarlyView.
Glioma cells mainly express the endothelin receptor EDNRB, while EDNRA is restricted to a perivascular tumor subpopulation. Endothelin signaling reduces glioma cell proliferation while promoting migration and a proneural‐to‐mesenchymal transition associated with poor prognosis. This pathway activates Ca2+, K+, ERK, and STAT3 signalings and is regulated
Donovan Pineau   +36 more
wiley   +1 more source

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