Results 91 to 100 of about 4,499,855 (300)
Structural and biochemical analysis of a B12 superbinder
FEBS Letters, EarlyView.BtuG proteins are vitamin B12 scavengers in Bacteroides thetaiotaomicron, a dominant human gut bacterium. We present crystal structures of three BtuG homologs bound to cobalamin and its precursor cobinamide, revealing picomolar binding affinities, among the highest known for any natural protein.
Jose M. Martinez Felices +3 more
wiley +1 more source
FEBS Letters, EarlyView.Mycobacterial 3‐methylcrotonyl‐CoA carboxylase uses a mobile biotin‐carrying domain to shuttle a carboxyl group between two catalytic sites, enabling carboxylation of 3‐methylcrotonyl‐CoA during leucine breakdown. Cryo‐electron microscopy captures the carrier at both sites and reveals an inward loop movement that may prevent futile rebinding to the ...
Ajit Yadav +2 more
wiley +1 more source
Model based code generation for distributed embedded systems [PDF]
, 2010 Embedded systems are becoming increasingly complex and more distributed. Cost and quality requirements necessitate reuse of the functional software components for multiple deployment architectures.
Gopalswamy, Swaminathan +4 more
core
Program Code Generation with Generative AIs
AlgorithmsOur paper compares the correctness, efficiency, and maintainability of human-generated and AI-generated program code. For that, we analyzed the computational resources of AI- and human-generated program code using metrics such as time and space ...
Baskhad Idrisov, Tim Schlippe
doaj +1 more source
FEBS Letters, EarlyView.How do genomes gain new functional parts? In eukaryotes, which tend to evolve under weak selection, much of the genome is junk. Palazzo and Qiu borrow the logic of Markov chains to show how non‐functional DNA becomes functional through the appearance of intermediate states, which arise due to epistasis, buffering, and biochemical messiness, allowing ...
Alexander F. Palazzo, Yi Qiu
wiley +1 more source
The Shewanella oneidensis Fic enzyme SoFic targets the switch‐I region of EF‐Tu for AMPylation
FEBS Letters, EarlyView.Fic enzymes mediate diverse post‐translational modifications across all domains of life, including AMPylation. Prokaryotic EF‐Tu can be AMPylated and deAMPylated by the conserved Fic enzyme SoFic. Structural and biochemical approaches were used to characterize the effect of AMPylation on EF‐Tu, SoFic's enzymatic activities, and the enzyme‐target ...
Svenja Runge +6 more
wiley +1 more source
Alaska Criminal Code Revision — Tentative Draft, Part 3: Offenses against Property [PDF]
, 1977 As of 1975, Alaska’s criminal laws were based primarily on Oregon criminal statutes as they existed at the close of the nineteenth century, with new statutes added and old statutes amended over the succeeding 75 years by Alaska territorial and state ...
Alaska Criminal Code Revision Subcommission
core
Repeat accumulate code division multiple access and its hybrid detection
, 2008 In this paper, we propose the novel concept of Repeat Accumulate Code Division Multiple Access (RA-CDMA), which employs unique, user-specific channel code generator matrices (interleavers) for differentiating the users.
S. Chen +7 more
core +2 more sources
Security Analysis of Automated Code Generation: Structural Vulnerabilities in AI-Generated Code
Tehnički GlasnikAI-driven code generation enhances operational efficiency; however, it also introduces security vulnerabilities due to insufficient human oversight during development.
Sang Hyun Yoo, Hyun Jung Kim
doaj +1 more source
FEBS Letters, EarlyView.Synechocystis strains deficient in succinate dehydrogenase (SDH) secrete more succinate than the WT under dark anaerobic conditions, supporting that SDH then primarily acts as SDH, not as a fumarate reductase. L‐aspartate oxidase (Laspo) from Synechocystis is functional under anaerobic conditions, reducing fumarate to succinate.
Kateryna Kukil +3 more
wiley +1 more source