Results 71 to 80 of about 11,564,024 (351)

The (Glg)ABCs of cyanobacteria: modelling of glycogen synthesis and functional divergence of glycogen synthases in Synechocystis sp. PCC 6803

open access: yesFEBS Letters, EarlyView.
We reconstituted Synechocystis glycogen synthesis in vitro from purified enzymes and showed that two GlgA isoenzymes produce glycogen with different architectures: GlgA1 yields denser, highly branched glycogen, whereas GlgA2 synthesizes longer, less‐branched chains.
Kenric Lee   +3 more
wiley   +1 more source

SAST Implementation for Evaluating LLM-Generated Code Quality using Prompt Engineering

open access: yesSistemasi: Jurnal Sistem Informasi
The use of Large Language Models (LLMs) for generating programming code has become increasingly widespread; however, the quality of the generated output heavily depends on the instructions or prompts provided. This study aims to evaluate the influence of
Muhammad Luthfi Abdillah   +1 more
doaj   +1 more source

Quality Estimation & Interpretability for Code Translation

open access: yesCoRR, 2020
NeurIPS 2020 Workshop on Computer-Assisted ...
Mayank Agarwal   +7 more
openaire   +2 more sources

Tau acetylation at K331 has limited impact on tau pathology in vivo

open access: yesFEBS Letters, EarlyView.
We mapped tau post‐translational modifications in humanized MAPT knock‐in mice and in amyloid‐bearing double knock‐in mice. Acetylation within the repeat domain, particularly around K331, showed modest increases under amyloid pathology. To test functional relevance, we generated MAPTK331Q knock‐in mice.
Shoko Hashimoto   +3 more
wiley   +1 more source

Improving your test code with Wrangler [PDF]

open access: yes, 2009
In this paper we show how the 'similar code' detection facilities of Wrangler, combined with its portfolio of refactorings, allow test code to be shrunk dramatically, under the guidance of the test engineer.
Lindberg, Adam   +3 more
core  

Investigating the Refactoring Capabilities of Small Open-Weight Language Models

open access: yesSoftware
Refactoring is essential for developing maintainable software. Using Large Language Models in software engineering is widespread, but compared to well-established domains such as code generation, reliable refactoring is still relatively underexplored. In
Tamás Márton   +3 more
doaj   +1 more source

Structural insights into an engineered feruloyl esterase with improved MHET degrading properties

open access: yesFEBS Letters, EarlyView.
A feruloyl esterase was engineered to mimic key features of MHETase, enhancing the degradation of PET oligomers. Structural and computational analysis reveal how a point mutation stabilizes the active site and reshapes the binding cleft, expading substrate scope.
Panagiota Karampa   +5 more
wiley   +1 more source

Gut microbiome and aging—A dynamic interplay of microbes, metabolites, and the immune system

open access: yesFEBS Letters, EarlyView.
Age‐dependent shifts in microbial communities engender shifts in microbial metabolite profiles. These in turn drive shifts in barrier surface permeability of the gut and brain and induce immune activation. When paired with preexisting age‐related chronic inflammation this increases the risk of neuroinflammation and neurodegenerative diseases.
Aaron Mehl, Eran Blacher
wiley   +1 more source

Pizza versus Pinsa: On the Perception and Measurability of Unit Test Code Quality

open access: yesIEEE International Conference on Software Maintenance and Evolution, 2020
Test cases are an essential asset to evaluate software quality. The research community has provided various alternatives to help developers assessing the quality of tests, like code or mutation coverage.
Giovanni Grano   +3 more
semanticscholar   +1 more source

Does Code Quality Affect Pull Request Acceptance? An empirical study [PDF]

open access: yesJournal of Systems and Software, 2019
Background. Pull requests are a common practice for contributing and reviewing contributions, and are employed both in open-source and industrial contexts. One of the main goals of code reviews is to find defects in the code, allowing project maintainers
Valentina Lenarduzzi   +3 more
semanticscholar   +1 more source

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