Results 91 to 100 of about 11,564,024 (351)
Phosphoinositides and inositol phosphates as molecular glues
FEBS Letters, EarlyView.Inositol phosphates (IPs) and phosphoinositides (PIPs) regulate diverse eukaryotic processes. Beyond recruiting signaling proteins or acting as structural cofactors, recent studies suggest they mediate protein–protein interactions as natural molecular glues.
Aleshia Seaton‐Terry +9 more
wiley +1 more source
Water quality model code and guidebook
, 2000 Title from PDF cover (viewed on May 20, 2019).This archived document is maintained by the State Library of Oregon as part of the Oregon Documents Depository Program.
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Automated Code-Smell Detection in Microservices Through Static Analysis: A Case Study
Applied Sciences, 2020 Microservice Architecture (MSA) is becoming the predominant direction of new cloud-based applications. There are many advantages to using microservices, but also downsides to using a more complex architecture than a typical monolithic enterprise ...
Andrew Walker, Dipta Das, Tomas Cerny
doaj +1 more source
FEBS Letters, EarlyView.Inositol pyrophosphates are energy‐rich signaling molecules that perform critical functions in cells. Three different families of phosphatases hydrolyze the β phosphate of the inositol pyrophosphate molecules: two have narrow specificities and one is promiscuous.
Ronda J. Rolfes
wiley +1 more source
Design and analysis strategies for robust microbiome ageing research
FEBS Letters, EarlyView.The gut microbiome changes with age and associates with age‐related morbidity and mortality, establishing it as a potential biomarker and intervention target for ageing. Realising this potential requires methodological rigour, yet distinguishing biological signals from methodological artefacts remains challenging across cohorts. This review provides an
Mark Olenik +5 more
wiley +1 more source
Analysis of Code Refactoring Impact on Software Quality
MATEC Web of Conferences, 2016 Code refactoring is a “Technique used for restructuring an existing source code, improving its internal structure without changing its external behaviour”.
Kaur Amandeep, Kaur Manpreet
doaj +1 more source
The role of miR‐335‐5p in the redifferentiation of BRAF p.V600E thyroid cancers
Molecular Oncology, EarlyView.The BRAF p.V600E mutation promotes thyroid cancer dedifferentiation and radioiodine resistance. Using a network approach, we identified miR‐335‐5p as a key regulator of BRAF‐mutated thyroid tumors. Restoring miR‐335‐5p increased thyroid‐specific gene expression and iodine uptake in cells and organoids.
Valeria Pecce +11 more
wiley +1 more source
AICodeReview: Advancing code quality with AI-enhanced reviews
SoftwareXThis paper presents a research investigation into the application of Artificial Intelligence (AI) within code review processes, aiming to enhance the quality and efficiency of this critical activity.
Yonatha Almeida +7 more
doaj +1 more source
Molecular Oncology, EarlyView.Aptamers are used both therapeutically and as targeting agents in cancer treatment. We developed an aptamer‐targeted PLGA–TRAIL nanosystem that exhibited superior therapeutic efficacy in NOD/SCID breast cancer models. This nanosystem represents a novel biotechnological drug candidate for suppressing resistance development in breast cancer.
Gulen Melike Demirbolat +8 more
wiley +1 more source
A lot of the defects that are present in a program are not visible to the compiler. Static code analysis is a way to find bugs and reduce the defects in a software application.
Alexandru G. Bardas
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