Results 111 to 120 of about 2,837,348 (324)
On Nonnegative Integer Matrices and Short Killing Words
, 2019 Let $n$ be a natural number and $\mathcal{M}$ a set of $n \times n$-matrices over the nonnegative integers such that the joint spectral radius of $\mathcal{M}$ is at most one. We show that if the zero matrix $0$ is a product of matrices in $\mathcal{M}$,
Kiefer, Stefan, Mascle, Corto
core +1 more source
Molecular Oncology, EarlyView.We identified adaptor protein ShcD as upregulated in triple‐negative breast cancer and found its expression to be correlated with reduced patient survival and increased invasion in cell models. Using a proteomic screen, we identified novel ShcD binding partners involved in EGFR signaling pathways.
Hayley R. Lau +11 more
wiley +1 more source
The CMB in a Causal Set Universe
, 2007 We discuss Cosmic Microwave Background constraints on the causal set theory of quantum gravity, which has made testable predictions about the nature of dark energy. We flesh out previously discussed heuristic constraints by showing how the power spectrum
Zuntz, Joe
core +1 more source
Molecular Oncology, EarlyView.This study used longitudinal transcriptomics and gene‐pattern classification to uncover patient‐specific mechanisms of chemotherapy resistance in breast cancer. Findings reveal preexisting drug‐tolerant states in primary tumors and diverse gene rewiring patterns across patients, converging on a few dysregulated functional modules. Despite receiving the
Maya Dadiani +14 more
wiley +1 more source
Molecular Oncology, EarlyView.B‐cell chronic lymphocytic leukemia (B‐CLL) and monoclonal B‐cell lymphocytosis (MBL) show altered proteomes and phosphoproteomes, analyzed using mass spectrometry, protein microarrays, and western blotting. Identifying 2970 proteins and 316 phosphoproteins, including 55 novel phosphopeptides, we reveal BCR and NF‐kβ/STAT3 signaling in disease ...
Paula Díez +17 more
wiley +1 more source
Computing the Unique Information
, 2018 Given a pair of predictor variables and a response variable, how much information do the predictors have about the response, and how is this information distributed between unique, redundant, and synergistic components?
Banerjee, Pradeep Kr. +2 more
core +1 more source
Determination of ADP/ATP translocase isoform ratios in malignancy and cellular senescence
Molecular Oncology, EarlyView.The individual functions of three isoforms exchanging ADP and ATP (ADP/ATP translocases; ANTs) on the mitochondrial membrane remain unclear. We developed a method for quantitatively differentiating highly similar human ANT1, ANT2, and ANT3 using parallel reaction monitoring. This method allowed us to assess changes in translocase levels during cellular
Zuzana Liblova +18 more
wiley +1 more source
Edge-based metric resolvability of anti-depression molecular structures and its application
Results in ChemistryChemical graph theory represents an interdisciplinary field at the intersection of chemistry and mathematics, focusing on the analysis of various chemical structures through graph-theoretical frameworks.
Rab Nawaz +2 more
doaj +1 more source
Frontiers in Cellular Neuroscience, 2017 A major stumbling block to cracking the real-time neural code is neuronal variability - neurons discharge spikes with enormous variability not only across trials within the same experiments but also in resting states.
Meng Li +3 more
doaj +1 more source
Landscape of BRAF transcript variants in human cancer
Molecular Oncology, EarlyView.We investigate the annotation of BRAF variants, focusing on protein‐coding BRAF‐220 (formerly BRAF‐reference) and BRAF‐204 (BRAF‐X1). The IsoWorm pipeline allows us to quantify these variants in human cancer, starting from RNA‐sequencing data. BRAF‐204 is more abundant than BRAF‐220 and impacts patient survival.
Maurizio S. Podda +5 more
wiley +1 more source