Results 171 to 180 of about 19,688 (261)

Identification of genes associated with smell dysfunction in Parkinson's disease. [PDF]

Clin Park Relat Disord
Ali MZ, Kiran M, Dholaniya PS.
europepmc   +1 more source

TECTB Variants Reveal Tectorial Membrane Vulnerability in Dominant Non‐Syndromic Hearing Loss

Advanced Science, EarlyView.
TECTB is a non‐collagenous protein of the tectorial membrane – an extracellular matrix of the cochlea. This study identifies dominant missense variants in TECTB linked to human hereditary deafness in two unrelated families. Genetically engineered mice homozygous for one of the variants are profoundly deaf, whereas heterozygous mice have normal hearing ...
Evan B. Hale, Barbara Vona, Richard J. Goodyear, Richard T. Osgood, Jun Shen, Sami S. Amr, Karen Mojica, Michaela A. H. Hofrichter, Jörg Schröder, Sophie Flandin, Paul Gratias, Ricardo Vera‐Monroy, Katherine Callahan, Kerry L. Gudlewski, Rolen Quadros, Masato Ohtsuka, JoAnn McGee, Edward J. Walsh, Cynthia C. Morton, Thomas Haaf, Channabasavaiah Gurumurthy, James E. Saunders, Guy P. Richardson, Artur A. Indzhykulian   +23 more
wiley   +1 more source

Association between Diagnostic History and Cancer Incidence within 5 Years: A Real-world Observational Analysis. [PDF]

Cancer Res Commun
Alam MA, Williams G, Kibriya MG, Matrana M, Duesbery N, Trapido E, Fort D.   +6 more
europepmc   +1 more source

Reversible, Chemically Gated FRET via Ligand‐Activated Acceptors

Advanced Science, EarlyView.
Fluorogen binding turns the compact FAST tag into a tunable FRET acceptor, with ligand chemistry programming spectral overlap and excited‐state lifetimes. Fluorescence‐lifetime imaging reads out energy transfer through the shortened donor lifetime, while simply adding or washing out the dye switches FRET on and off, reversibly mapping the supramodular ...
Nivedita Singh, Smruti Ranjan Nayak, Sanjay Kumar Mohanty, Aishwarya Hanumantharaju, Amala Shaju, Mini Jose, Aravind Penmatsa, Deepak Nair   +7 more
wiley   +1 more source

RefactoCNN-system: an optimized deep learning framework for predicting software refactoring opportunities using CNN-based code analysis. [PDF]

Sci Rep
Prasanna EL, Srinivas K.
europepmc   +1 more source

Molecular Atlas of Key Food Odorants Reveals Mixture‐Level Organization and Enables Generative Aroma Design

Advanced Science, EarlyView.
KFO‐Atlas reveals how real‐world aromas are organized as structured mixtures rather than individual molecules. Building on these principles, KFO‐Gen, a generative AI framework, designs perceptually valid aroma formulations and reconstructs meat‐like aromas exclusively from plant‐derived odorants, providing a foundation for mixture‐level studies and AI ...
Jingzhi Zhang, Huadong Xing, Antonella Di Pizio, Qinfei Ke, Xingran Kou, Dachuan Zhang   +5 more
wiley   +1 more source

Idiopathic hyposmia as a marker of prodromal Parkinson's disease - a cohort study. [PDF]

Sci Rep
Markovic-Obiago Z, Bestwick JP, Chohan H, Schrag A, Simonet C, Noyce AJ.   +5 more
europepmc   +1 more source

Supramolecular Allostery Achieves Tunable Luminescence Aromatic Bridged Phenothiazine Noncovalent Frameworks

Advanced Science, EarlyView.
Tunable luminescent supramolecular organic framework enabled by multiple allosteric effects, composed of a tetracation vinylphenylpyridinium‐modified aromatic‐bridged phenothiazine guest and cucurbit[8]uril, not only exhibits unique guest oxidation‐driven NIR luminescence blue‐shift and effectively enhances the quantum yield by 46‐fold to 22.2% but ...
Xinping Lu, Jianchong Chen, Jie Yu
wiley   +1 more source

Sensory deficiencies correlate with tau protein and dementia. [PDF]

Front Neurosci
Avila-Villanueva M, Hernández F, Avila J, Plascencia-Villa G, Perry G.   +4 more
europepmc   +1 more source

Intrinsic Superprotonic Conduction in Metal‐Free Hydrogen‐Bonded Organic–Inorganic Frameworks

Advanced Science, EarlyView.
A simple hybridization strategy yields a suite of metal‐free hydrogen‐bonded organic‐inorganic frameworks (HOIFs) with dense, uninterrupted hydrogen‐bonded networks that possess intrinsically high superprotonic conductivity, establishing a versatile and scalable platform for high‐performance solid‐state proton conductors.
Jin Chen, Yongqiang Cheng, Simon J. Teat, Gobin Raj Acharya, Roknuzzaman Roknuzzaman, Wensong Yu, Yucong Xia, Weston C. Swallow, Xiaoying Huang, Xiaodong Yang, Thomas J. Emge, Kui Tan, Andrew J. Nieuwkoop, Lawrence J. Williams, Jing Li   +14 more
wiley   +1 more source