Results 181 to 190 of about 19,688 (261)

Objective assessment of long-term impact of COVID-19 on multiple sensory functions. [PDF]

BMC Med
Odeh A, Formanek VL, Smith C, Jha N, Tajino J, Lewis JH, Gastineau L, Patel S, Zhao S, Wei L, Moberly AC, Merfeld DM, Simons CT, Kobel MJ, Zhao K.   +14 more
europepmc   +1 more source

Stimulation of OGG1 Enhances Oxidative DNA Damage Repair and Protects Against Acute Liver Failure by Acetaminophen

Advanced Science, EarlyView.
Chemical switching of OGG1 by CMM‐98 accelerates oxidative DNA damage repair and enhances hepatocyte resilience during acetaminophen‐induced acute liver injury. By promoting efficient processing of OGG1‐generated repair intermediates, CMM‐98 reduces oxidative damage, preserves cellular integrity, and protects against acute liver failure, identifying ...
Zhenjun Zhao, Rahul Upadhyay, Alice Eddershaw, Chenchen Wang, Yudong Zhao, Olov Wallner, Jinhye Ryu, Nayere Taebnia, Heather Gildie, Emma Scaletti‐Hutchinson, Jonathan R. Davies, Nicole Ziegler, Andreas Krämer, Samantha C. Robinson, Marek Varga, Karolina Singerova, Zuzanna Szaruga, Elisée Wiita, İrşil Güneş, Sheila S. David, Stefan Knapp, Aimo Kannt, Miguel de Vega, Pål Stenmark, Volker M Lauschke, Maurice Michel   +25 more
wiley   +1 more source

Challenges to continuity of care among patients with long COVID-related taste and smell disorders: a qualitative study. [PDF]

Front Public Health
Martín-Sanz MB, Moro-López-Menchero P, Fernández-De-Las-Peñas C, Gómez-Sánchez SM, Gil-Crujera A, Ceballos-García L, Escribano-Mediavilla NI, Fuentes-Fuentes MV, Florencio LL, Palacios-Ceña D.   +9 more
europepmc   +1 more source

ACAT1‐Mediated SP1‐K694 Lactylation Promotes M1 Macrophage Polarization via TREM1 Transcription in COPD

Advanced Science, EarlyView.
Upon cigarette smoke exposure(CSE), LDHA expression is increased in lung macrophages, promoting the conversion of pyruvate to lactate and elevating the lactylation level of SP1 at the K694 site. This, in turn, enhances SP1 enrichment at the TREM1 promoter, increases TREM1 expression, promoted M1 macrophage polarization, and triggers the secretion of ...
Ling Lin, Ping Zhang, Qing Song, Tao Li, Yuqin Zeng, Ping Chen   +5 more
wiley   +1 more source

Evaluation of idiopathic olfactory dysfunction as a warning marker for early parkinson's disease: a population-based cross-sectional study. [PDF]

Sci Rep
Vedadi Z, Miandehi EE, Akbari M, Shoeibi A, Vedadi D, Eslami S, Taherzadeh Z.   +6 more
europepmc   +1 more source

Atomically Dispersed Fe‐Modified SnS for Sn‐Centered Peroxymonosulfate Activation Toward Acetaminophen Degradation

Advanced Science, EarlyView.
Atomically dispersed Fe regulates the local electronic environment and surface properties of SnS, while PMS preferentially coordinates to Sn through Sn–O interaction. Fe incorporation further enhances the Sn–OPMS interfacial interaction, facilitating Sn‐centered PMS activation and the generation of SO4•−/•OH for APAP degradation, thereby clarifying the
Shuhui Liu, Yantao Wang, Ya Liu, Jingkai Lin, Shaobin Wang, Wenjie Tian   +5 more
wiley   +1 more source

Neurodegeneration in the olfactory system in Niemann Pick type C1 disease. [PDF]

iScience
Fioriello MG, Lobraico D, Gatta RP, Iannuzzi L, Quaranta N, Lobasso S, Reisert J, Frigeri A, Dibattista M.   +8 more
europepmc   +1 more source

Computational and Data‐Driven Strategies for Lignocellulosic Biomass Valorization: From Multiscale Modeling to Digitalized Biorefinery Design

Advanced Science, EarlyView.
This Review critically connects structural recalcitrance, molecular modeling, solvent and catalyst design, pyrolysis, machine learning, reactor simulation, and FAIR digital infrastructure. Emphasis is placed on experimentally validated information transfer across scales, uncertainty and applicability domains, and the recycle, durability, techno ...
Abdullahi Bello Umar, Jiaxian Zheng, Xiangfeng Lin, Hongwu Liao, Haoqian Xu, Yufei Huang, Zaharaddeen Nasiru Garba, Adamu Uzairu, Weiwei Zhao, Zhanhui Yuan   +9 more
wiley   +1 more source

Application for the Detection of Taste and Smell Disorders Based on Self-Test at the Patient's Home. [PDF]

Diagnostics (Basel)
Buksinska M, Tomaszewska-Hert I, Talarek M, Skarzynski PH.   +3 more
europepmc   +1 more source

Enhancing Specific Stiffness of Nano‐Architected Materials Through Generative AI and Active Learning

Advanced Science, EarlyView.
A structure‐centric generative framework searches voxelated design space directly, coupling a variational autoencoder with multi‐objective optimization and active learning to progressively expand the validated design domain. The discovered nano‐architectures, realized as pyrolytic carbon by two‐photon lithography, deliver 18–23% higher stiffness and 26–
Jinwook Yeo, Peter Serles, Donggeun Park, Julia R. Greer, Seunghwa Ryu   +4 more
wiley   +1 more source