Diffusion MRI and α‐Synuclein Seed Amplification Status in Parkinson's Disease
Objective Positive α‐synuclein seed amplification assay (SAA) is a biomarker found in most people with Parkinson's disease (PD). We explored if free‐water (FW) imaging detects microstructural differences in the brains of patients with early PD with SAA+ or SAA– status.
Shannon Y. Chiu +145 more
wiley +1 more source
Sensing Dog Brain Reactions to Smell by AI Speckle Pattern Analysis. [PDF]
Propp I +5 more
europepmc +1 more source
Light‐Controlled Modulation of 15‐Lipoxygenase‐1 Regulates Intestinal Inflammatory Signaling
The developed target‐guided strategy enables the rational design of diazo‐based photoswitchable inhibitors of 15‐lipoxygenase‐1. Distinct molecular architectures program opposite light‐dependent activity, allowing on‐demand control of enzyme inhibition.
Anastasia Louka +10 more
wiley +2 more sources
Machine learning-based test smell detection. [PDF]
Pontillo V +5 more
europepmc +1 more source
Copilot-in-the-Loop: Fixing Code Smells in Copilot-Generated Python Code using Copilot
As one of the most popular dynamic languages, Python experiences a decrease in readability and maintainability when code smells are present. Recent advancements in Large Language Models have sparked growing interest in AI-enabled tools for both code ...
Feng, Qiong +4 more
core
Enzyme‐Like Synthetic Cleft for Light‐Driven Water‐Oxidation Catalysis Via an Oxide Relay Pathway
A carboxylic acid group introduced into the second coordination sphere of a Ru(bda) water oxidation catalyst forms a defined hydrogen bond within the catalytic cleft. This interaction locks the group in place and enables an intramolecular oxide relay pathway between Ru(V)═O and the carboxylate group, providing a distinct and efficient route for O─O ...
Daniel A. P. Friedewald +7 more
wiley +2 more sources
Framing a pig welfare assessment protocol suitable for smallholder settings in low-to-middle income countries. [PDF]
Oehlers L +3 more
europepmc +1 more source
Rapid Fragment Screening by 19F Steady‐State Free Precession NMR
19F$^{19}{\rm F}$ SSFP NMR is a broadband and very sensitive experiment for detecting protein–ligand interactions. The method enables rapid fragment screening at low micromolar protein concentrations, even for challenging drug targets such as intrinsically disordered proteins.
Laura Ruduša +8 more
wiley +2 more sources
Evaluation of patients' satisfaction with food services and assessment of plate waste in Cypriot hospitals. [PDF]
Hadjimbei E +4 more
europepmc +1 more source
A Unified Multi-Label Code Smell Dataset for Code Smell Detection at Different Granularities
Haneen M. Alhadeaf, Mubarak Alrashoud
openaire +1 more source

