Results 51 to 60 of about 1,546,262 (243)

Heterotropic regulation and negative homotropic cooperativity

FEBS Open Bio, EarlyView.
We identified a structural module common to some proteins that couple negative cooperativity with heterotropic regulation, two features that rarely coexist. These proteins are ring‐like and present an ordered asymmetry whereby noncontacting subunits are symmetric, and their tertiary structure differs from that of contacting subunits.
Veronica Morea, Francesco Angelucci, Federica Arnesano, Gianmarco Pascarella, Patrizio Di Micco, Andrea Bellelli   +5 more
wiley   +1 more source

An Approach Based on Sum Product Networks for Code Smells Detection

Journal of Communications Software and Systems
From a software engineering perspective, a code smell refers to poor code structure. Many studies have shown that there is a significant negative relationship between code smells and code quality.
Mostefai Abdelkader
doaj   +1 more source

Structural and biochemical insights into the thermostable esterase Ta0887 from Thermoplasma acidophilum

FEBS Open Bio, EarlyView.
In this study, a novel esterase from the thermoacidophilic archaeon Thermoplasma acidophilum was biochemically and structurally characterized. Our results demonstrate that Ta0887 is a highly thermostable esterase that preferentially hydrolyzes p‐nitrophenyl hexanoate and possesses an α‐helical cap domain that likely contributes to its substrate ...
Alejandro Delgado‐Rey, Miriam Livier Llamas‐García, Gabriela M. Montero‐Morán, Leticia Santos, Samuel Lara‐González   +4 more
wiley   +1 more source

Code Smells Thresholds Optimization: Defect Prediction as a Case Study

Algorithms
In software engineering, detecting and managing code smells are pivotal for maintaining software quality and reducing the risk of defects. Code smells signify potential issues in code that, while not problematic in themselves, may indicate deeper design ...
Tom Mashiach, Gilad Katz, Meir Kalech
doaj   +1 more source

Analysis of Code Refactoring Impact on Software Quality

MATEC Web of Conferences, 2016
Code refactoring is a “Technique used for restructuring an existing source code, improving its internal structure without changing its external behaviour”.
Kaur Amandeep, Kaur Manpreet
doaj   +1 more source

Study of Code Smells: A Review and Research Agenda [PDF]

International Journal of Mathematical, Engineering and Management Sciences
Code Smells have been detected, predicted and studied by researchers from several perspectives. This literature review is conducted to understand tools and algorithms used to detect and analyze code smells to summarize research agenda.
Stuti Tandon, Vijay Kumar, V. B. Singh
doaj   +1 more source

Prioritizing the refactoring need for critical component using combined approach [PDF]

Decision Science Letters, 2018
One of the most promising strategies that will smooth out the maintainability issues of the software is refactoring. Due to lack of proper design approach, the code often inherits some bad smells which may lead to improper functioning of the code ...
Rajni Sehgal, Deepti Mehrotra, Manju Bala   +2 more
doaj   +1 more source

Genetic dissection of human ABCE1 in yeast reveals separable requirements for ribosome recycling and suppression of aberrant reinitiation

FEBS Open Bio, EarlyView.
Human ABCE1 cannot functionally replace its yeast ortholog. Yeast–human chimera analysis identified NBD1 as a major interspecies barrier. Genetic screening yielded hABCE1 revertants that rescue yeast viability but fail to suppress aberrant translation reinitiation in the 3′ UTR.
Eriko Nakata, Yuxin Li, Kei Endo, Koichi Ito   +3 more
wiley   +1 more source

3 Dimensional visualization of code smells

, 2022
Bad code smells are symptoms of design flaws in source code. Several tools and approaches have been proposed for detecting and visualizing code smells.
Hasantha PAC
core  

Memory and Resting‐State Connectivity in Acute Transient Global Amnesia: A Case–Control fMRI Study

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Background and Objectives Transient global amnesia (TGA) is a striking model of isolated amnesia. While hippocampal lesions are well described, the network‐level mechanisms and the precise neuropsychological profile remain debated. Our objective was thus to characterize functional and neuropsychological correlates of acute TGA and their ...
Elias El Otmani, Emmanuel Barbeau, Béatrice Lemesle, Emilie Milongo‐Rigal, Sophie Fernandez, Sandrine Charpentier, Jean‐François Albucher, Nicolas Raposo, Fabrice Bonneville, Patrice Péran, Jérémie Pariente   +10 more
wiley   +1 more source