Results 51 to 60 of about 4,236 (288)
, 2023 A replication package for Android-specific code smells. Supplementary Material - A Systematic Literature Review on Applying Intelligent Techniques to Manage Technical ...
Zhiqiang Wu (10689114)
core +1 more source
Interpreting the effects of DNA polymerase variants at the structural level
Molecular Oncology, EarlyView.Using MAVISp and molecular dynamics simulations, we analyzed over 60 000 missense variants in POLE and POLD1 from ClinVar, COSMIC, cBioPortal, and saturation mutagenesis. Identified mechanistic indicators, including stability, binding, and long‐range, enable structural interpretation, providing ACMG‐like evidence for possible reclassification of VUS ...
Matteo Arnaudi +7 more
wiley +1 more source
Code Smell Detection Using Ensemble Machine Learning Algorithms
Applied Sciences, 2022 Code smells are the result of not following software engineering principles during software development, especially in the design and coding phase. It leads to low maintainability.
Seema Dewangan +3 more
doaj +1 more source
Molecular Oncology, EarlyView.The novel styrylquinazolinone‐based molecule W1B effectively suppresses glioblastoma by inhibiting IGF1R and EGFR. In high‐glucose microenvironments driving tumor resistance, W1B acts synergistically with the EGFR inhibitor dacomitinib. This combination safely blocks compensatory survival signaling in zebrafish xenograft models. Showcasing promising in
Patryk Rurka +9 more
wiley +1 more source
Detecting and managing code smells [PDF]
Proceedings of the 40th International Conference on Software Engineering: Companion Proceeedings, 2018 Code smells indicate the presence of quality problems that make the software hard to maintain and evolve. A software development team can keep their software maintainable by identifying smells and refactor them. In the first part of the session, we present a comprehensive overview of the literature concerning smells covering various dimensions of the ...
openaire +2 more sources
Definition, implementation and validation of energy code smells: an exploratory study on an embedded system [PDF]
, 2013 Optimizing software in terms of energy efficiency is one of the challenges that both research and industry will have to face in the next few years.We consider energy efficiency as a software product quality characteristic, to be improved through the ...
Ardito, Luca +8 more
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Raman‐based label‐free microscopic analysis of the pancreas in living zebrafish larvae
FEBS Open Bio, EarlyView.Forward stimulated Raman scattering (F‐SRS) and epi coherent anti‐Stokes Raman scattering (E‐CARS) allow label‐free discrimination of distinct subcellular structures in the pancreas of living zebrafish larvae. Given the straightforward applicability, we anticipate broad implementation of Raman microscopy in other organs and across various biomedical ...
Noura Faraj +3 more
wiley +1 more source
Olfactory Coding: When Smells Collide [PDF]
Current Biology, 2006 Brain responses can significantly outlast sensory stimuli leading to potential ambiguity when responses overlap. Recent studies of locust olfaction found that the responses of individual second order projection neurons depend markedly on the previous few seconds' stimulus history; the population response, however, still conveys information about both ...
Antolin, Salomé +1 more
openaire +2 more sources
Code smells: A Synthetic Narrative Review
CoRR, 2021 Code smells are symptoms of poor design and implementation choices, which might hinder comprehension, increase code complexity and fault-proneness and decrease maintainability of software systems. The aim of our study was to perform a triangulation of bibliometric and thematic analysis on code smell literature production.
Kokol, Peter, Prof +2 more
openaire +2 more sources
FEBS Open Bio, EarlyView.Enzymes of the 2‐hydroxyacyl‐CoA lyase group catalyze the condensation of formyl‐CoA with aldehydes or ketones. Thus, by structural adaptation of active sites, practically any pharmaceutically and industrially important 2‐hydroxyacid could be biotechnologically synthesized. Combining crystal structure analysis, active site mutations and kinetic assays,
Michael Zahn +4 more
wiley +1 more source