Results 121 to 130 of about 3,090,615 (294)
Aldehyde dehydrogenase 1A1 (ALDH1A1) is a cancer stem cell marker in several malignancies. We established a novel epithelial cell line from rectal adenocarcinoma with unique overexpression of this enzyme. Genetic attenuation of ALDH1A1 led to increased invasive capacity and metastatic potential, the inhibition of proliferation activity, and ultimately ...
Martina Poturnajova +25 more
wiley +1 more source
Progress has been made toward the definition of “master-plan elements,” genes that encode spatiotemporal patterns of expression during development.
openaire +2 more sources
Targeted modulation of IGFL2‐AS1 reveals its translational potential in cervical adenocarcinoma
Cervical adenocarcinoma patients face worse outcomes than squamous cell carcinoma counterparts despite similar treatment. The identification of IGFL2‐AS1's differential expression provides a molecular basis for distinguishing these histotypes, paving the way for personalized therapies and improved survival in vulnerable populations globally.
Ricardo Cesar Cintra +6 more
wiley +1 more source
Affine Cartesian codes with complementary duals
A linear code $C$ with the property that $C \cap C^{\perp} = \{0 \}$ is said to be a linear complementary dual, or LCD, code. In this paper, we consider generalized affine Cartesian codes which are LCD.
López, Hiram H. +2 more
core
Tumors contain diverse cellular states whose behavior is shaped by context‐dependent gene coordination. By comparing gene–gene relationships across biological contexts, we identify adaptive transcriptional modules that reorganize into distinct vulnerability axes.
Brian Nelson +9 more
wiley +1 more source
Pre‐analytical handling critically determines liquid biopsy performance. This study defines practical best‐practice conditions for cell‐free DNA (cfDNA) and extracellular vesicle–derived DNA (evDNA), showing how processing time, storage conditions, tube type, and plasma input volume affect DNA integrity and mutation detection.
Jonas Dohmen +11 more
wiley +1 more source
Glioma cells mainly express the endothelin receptor EDNRB, while EDNRA is restricted to a perivascular tumor subpopulation. Endothelin signaling reduces glioma cell proliferation while promoting migration and a proneural‐to‐mesenchymal transition associated with poor prognosis. This pathway activates Ca2+, K+, ERK, and STAT3 signalings and is regulated
Donovan Pineau +36 more
wiley +1 more source
FROM THE PERSUASION TECHNIQUE TO DISGUISED MARKETING [PDF]
On the basis of examples from the press in Bosnia and Herzegovina and comparison with the state in Slovenia and Croatia the authors explain the reasons of emergence and modes of disguised marketing functioning.
Davorka Topić Stipić +2 more
doaj
$m$-adic residue codes over $\mathbb{F}_q[v]/(v^s-v)$
Due to their rich algebraic structure, cyclic codes have a great deal of significance amongst linear codes. Duadic codes are the generalization of the quadratic residue codes, a special case of cyclic codes.
Koroglu, Mehmet E. +2 more
core
Keratin 19 (KRT19) is overexpressed in high‐grade serous ovarian cancer with high levels of Kallikrein‐related peptidases (KLK) 4–7 and is associated with poor survival. In vivo analyses demonstrate that elevated KRT19 increases peritoneal tumour burden.
Sophia Bielesch +13 more
wiley +1 more source

