Results 41 to 50 of about 166,457 (253)
Structural insights into an engineered feruloyl esterase with improved MHET degrading properties
A feruloyl esterase was engineered to mimic key features of MHETase, enhancing the degradation of PET oligomers. Structural and computational analysis reveal how a point mutation stabilizes the active site and reshapes the binding cleft, expading substrate scope.
Panagiota Karampa +5 more
wiley +1 more source
Codes of conduct for just coexistence in urban spaces
Our study, comprising interviews and ethnographic observation, examines the human-rat conflict that arose in two urban allotment gardens in Helsinki as a case of multispecies negotiations.
Karolina M. Lukasik +2 more
doaj +1 more source
Gut microbiome and aging—A dynamic interplay of microbes, metabolites, and the immune system
Age‐dependent shifts in microbial communities engender shifts in microbial metabolite profiles. These in turn drive shifts in barrier surface permeability of the gut and brain and induce immune activation. When paired with preexisting age‐related chronic inflammation this increases the risk of neuroinflammation and neurodegenerative diseases.
Aaron Mehl, Eran Blacher
wiley +1 more source
Codes of conduct should help scientists navigate societal expectations
Scientists are increasingly expected to incorporate socio-political considerations in their work, for instance by anticipating potential socio-political ramifications.
Jacopo Ambrosj +2 more
doaj +1 more source
Biomolecular condensates formed by fused in sarcoma (FUS) are dissolved by high ATP concentrations yet persist in cells. Using a reconstituted system, we demonstrate that valosin‐containing protein (VCP), an AAA+ ATPase, counteracts ATP‐driven dissolution of FUS condensates through its D2 ATPase activity.
Hitomi Kimura +2 more
wiley +1 more source
Corporate Social Responsibility Standards: Is it Possible to Meet Diverse Customer Requirements?
The purpose of the study is to review the internationally recognised CSR (Corporate Social Responsibility) standards, codes of conduct (cross-industry and industry-specific used in electronics, automotive and steel industry) and selected codes and ...
Sütőová Andrea, Kóča Ferdinand
doaj +1 more source
Diversity and complexity in neural organoids
Neural organoid research aims to expand genetic diversity on one side and increase tissue complexity on the other. Chimeroids integrate multiple donor genomes within single organoids. Self‐organising multi‐identity organoids, exogenous cell seeding, or enforced assembly of region‐specific organoids contribute to tissue complexity.
Ilaria Chiaradia, Madeline A. Lancaster
wiley +1 more source
Radio Mentions: An Analysis of Radio Personalities and Ethical Behaviour (Spain)
Radio mentions (RM) are advertising messages read live by the presenters and coworkers of radio programs. However, this type of commercial is expressly forbidden by the code of ethics for journalists due to the conflict of interest and loss of ...
Salvador Perelló-Oliver +1 more
doaj
This article studies the process of professionalization in general and particularly in architecture and reviews the concept of professional ethics and the codes and documents related to it.
Hossein Sadri
doaj +1 more source
Plasma membranes contain dynamic nanoscale domains that organize lipids and receptors. Because viruses operate at similar scales, this architecture shapes early infection steps, including attachment, receptor engagement, and entry. Using influenza A virus and HIV‐1 as examples, we highlight how receptor nanoclusters, multivalent glycan interactions ...
Jan Schlegel, Christian Sieben
wiley +1 more source

