Results 141 to 150 of about 29,557 (302)

Independent accountant’s report on applying agreed upon procedures

open access: yes
The Office of State Auditor audited the financial statements of the South Carolina Codification of Laws and Legislative Council using agreed upon ...
South Carolina Codification of Laws and Legislative Council   +1 more
core  

Le Projet ReNEUAL. Histoire d'une collaboration scientifique réussie et d'une idée encore à réaliser: la codification de la procédure administrative de l'Union européenne [PDF]

open access: yes, 2019
N’ayant pas à faire face aux contraintes du droit positif qui encadrent, par exemple, la codification à droit constant à la française , le réseau ReNEUAL a pu développer une méthode de codification innovante basée sur le droit comparé . Quant
D. U. Galetta
core  

MITF maintains genome stability in nonmelanocyte lineages

open access: yesMolecular Oncology, EarlyView.
MITF is essential for melanocyte survival and acts as an oncogene in 10%–20% of melanomas. We show that MITF depletion causes genome instability in nonmelanocytic cells, leading to LATS2‐mediated P53 activation, cell cycle arrest, and apoptosis. This study highlights the role of MITF as a genome maintenance factor beyond the melanocyte lineage. Created
Drifa H. Gudmundsdottir   +13 more
wiley   +1 more source

A novel quinazolinone insulin receptor inhibitor and its synergy with an EGFR inhibitor in glucose‐driven glioblastoma

open access: yesMolecular Oncology, EarlyView.
The novel styrylquinazolinone‐based molecule W1B effectively suppresses glioblastoma by inhibiting IGF1R and EGFR. In high‐glucose microenvironments driving tumor resistance, W1B acts synergistically with the EGFR inhibitor dacomitinib. This combination safely blocks compensatory survival signaling in zebrafish xenograft models. Showcasing promising in
Patryk Rurka   +9 more
wiley   +1 more source

On the Translation of Design Data into Design Form in Evolutionary Design

open access: yes, 2000
The marriage of advanced computational methods and new manufacturing technologies give rise to new paradigms in design process and execution. Specifically, the research concerns itself with the application of Generative and Evolutionary computation to ...
C. Ceccato
core  

Codification of the Civil Law in Poland

open access: yes
In this chapter, the developmental trajectory of civil law codification in Poland is traced in parallel with the major events of Polish history. It reveals that codification work began in earnest during the so-called Second Republic, being subject to ...
Stec, Piotr
core   +1 more source

Tumor B‐cell infiltration in platinum‐treated advanced muscle‐invasive urothelial carcinoma

open access: yesMolecular Oncology, EarlyView.
Bladder tumors with higher pretreatment memory B‐cell infiltration were linked to longer survival after cisplatin chemotherapy, but not carboplatin. These tumors also showed more organized immune structures (tertiary lymphoid structures) and a shared pro‐inflammatory B‐cell‐rich community, suggesting that memory B cells may help identify patients most ...
Konrad Stawiski   +10 more
wiley   +1 more source

Patient therapy outcome modeling in cancer organoids is improved by cancer‐associated fibroblasts and organoid assembly convolution

open access: yesMolecular Oncology, EarlyView.
Patient‐derived organoids (PDOs) from pancreatic, colorectal, and gastric cancers were used to evaluate standard and experimental therapies. Incorporating cancer‐associated fibroblasts (CAFs) into organoid cultures improved patient therapy outcome prediction.
Marcin Grochowski   +12 more
wiley   +1 more source

Codification and Rule of Law

open access: yes, 2011
Depuis ses origines, la codification a toujours été officiellement réalisée en vue d’assurer l’accessibilité et l’intelligibilité de la norme ainsi que la sécurité juridique des individus.
Zaradny, Aude
core  

Loss of proton‐sensing TDAG8 increases tumor progression in mouse models of colon cancer

open access: yesMolecular Oncology, EarlyView.
Loss of the pH‐sensing receptor TDAG8 accelerates colorectal cancer progression in mice. Animals lacking TDAG8 expression had increased tumor growth, DNA damage, and recruitment of tumor‐associated immune cells, including macrophages, neutrophils, and monocytes.
Ermanno Malagola   +11 more
wiley   +1 more source

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