Results 91 to 100 of about 7,506,861 (344)

Translation and assembly of CABYR coding region B in fibrous sheath and restriction of calcium binding to coding region A

Developmental Biology, 2005
CABYR is a highly polymorphic, sperm flagellar calcium-binding protein that is tyrosine as well as serine/threonine phosphorylated during capacitation. Six alternative splice variants of human CABYR (I-VI) have previously been identified, involving two coding regions, CR-A and CR-B, separated by an intervening stop codon.
Arabinda Mandal, Phillip L. Snow, Kula N. Jha, Young-Hwan Kim, Ken Klotz, Erin M. Farris, Charles J. Flickinger, Soren Naaby-Hansen, John C. Herr, Geeta Vanage   +9 more
openaire   +3 more sources

Multidimensional OMICs reveal ARID1A orchestrated control of DNA damage, splicing, and cell cycle in normal‐like and malignant urothelial cells

Molecular Oncology, EarlyView.
Loss of the frequently mutated chromatin remodeler ARID1A, a subunit of the SWI/SNF cBAF complex, results in less open chromatin, alternative splicing, and the failure to stop cells from progressing through the cell cycle after DNA damage in bladder (cancer) cells. Created in BioRender. Epigenetic regulators, such as the SWI/SNF complex, with important
Rebecca M. Schlösser, Florian Krumbach, Eyleen Corrales, Geoffroy Andrieux, Christian Preisinger, Franziska Liss, Alexandra Golzmann, Melanie Boerries, Kerstin Becker, Ruth Knüchel, Stefan Garczyk, Bernhard Lüscher   +11 more
wiley   +1 more source

A Local Texture-Based Superpixel Feature Coding for Saliency Detection Combined with Global Saliency

Applied Sciences, 2015
Because saliency can be used as the prior knowledge of image content, saliency detection has been an active research area in image segmentation, object detection, image semantic understanding and other relevant image-based applications.
Bingfei Nan, Zhichun Mu, Long Chen, Jian Cheng   +3 more
doaj   +1 more source

First record of a tandem-repeat region within the mitochondrial genome of Clonorchis sinensis using a long-read sequencing approach.

PLoS Neglected Tropical Diseases, 2020
BackgroundMitochondrial genomes provide useful genetic markers for systematic and population genetic studies of parasitic helminths. Although many such genome sequences have been published and deposited in public databases, there is evidence that some of
Liina Kinkar, Neil D Young, Woon-Mok Sohn, Andreas J Stroehlein, Pasi K Korhonen, Robin B Gasser   +5 more
doaj   +1 more source

A Unified Mathematical Framework for Coding Time, Space, and Sequences in the Hippocampal Region

Journal of Neuroscience, 2014
The medial temporal lobe (MTL) is believed to support episodic memory, vivid recollection of a specific event situated in a particular place at a particular time.
Marc W Howard, C. MacDonald, Zoran Tiganj, Karthik H. Shankar, Qian Du, M. Hasselmo, H. Eichenbaum   +6 more
semanticscholar   +1 more source

Escape from TGF‐β‐induced senescence promotes aggressive hallmarks in epithelial hepatocellular carcinoma cells

Molecular Oncology, EarlyView.
Chronic TGF‐β exposure drives epithelial HCC cells from a senescent state to a TGF‐β resistant mesenchymal phenotype. This transition is characterized by the loss of Smad3‐mediated signaling, escape from senescence, enhanced invasiveness and metastatic potential, and upregulation of key resistance modulators such as MARK1 and GRM8, ultimately promoting
Minenur Kalyoncu, Dilara Demirci, Sude Eris, Bengisu Dayanc, Ece Cakiroglu, Merve Basol, Merve Uysal, Gulcin Cakan‐Akdogan, Fang Liu, Mehmet Ozturk, Gökhan Karakülah, Serif Senturk   +11 more
wiley   +1 more source

Region-of-Interest Based Coding Scheme for Live Videos

Applied Sciences
In this paper, we introduce a novel rate control scheme specifically tailored for live broadcasting scenarios. Notably, in high-definition live transmissions of sports events and video game competitions that typically exceed 1080 p resolution and run at ...
Xiuxin Dou, Xixin Cao, Xianguo Zhang
doaj   +1 more source

Targeting the AKT/mTOR pathway attenuates the metastatic potential of colorectal carcinoma circulating tumor cells in a murine xenotransplantation model

Molecular Oncology, EarlyView.
Dual targeting of AKT and mTOR using MK2206 and RAD001 reduces tumor burden in an intracardiac colon cancer circulating tumor cell xenotransplantation model. Analysis of AKT isoform‐specific knockdowns in CTC‐MCC‐41 reveals differentially regulated proteins and phospho‐proteins by liquid chromatography coupled mass spectrometry. Circulating tumor cells
Daniel J. Smit, Thais Pereira‐Veiga, Helena Brauer, Michael Horn, Paula Nissen, Thomas Mair, Bente Siebels, Hannah Voß, Ruimeng Zhuang, Marie‐Therese Haider, Desiree Loreth, Margarita Iskhakova, Bele Lindemann, Julian Kött, Laure Cayrefourcq, Jasmin Wellbrock, Hartmut Schlüter, Klaus Pantel, Catherine Alix‐Panabières, Manfred Jücker   +19 more
wiley   +1 more source

Inhibitor of DNA binding‐1 is a key regulator of cancer cell vasculogenic mimicry

Molecular Oncology, EarlyView.
Elevated expression of transcriptional regulator inhibitor of DNA binding 1 (ID1) promoted cancer cell‐mediated vasculogenic mimicry (VM) through regulation of pro‐angiogenic and pro‐cancerous genes (e.g. VE‐cadherin (CDH5), TIE2, MMP9, DKK1). Higher ID1 expression also increased metastases to the lung and the liver.
Emma J. Thompson, Emma L. Dorward, Kristyn Jurrius, Nathalie Nataren, Markus Tondl, Kay K. Myo Min, Michaelia P. Cockshell, Anahita Fouladzadeh, John Toubia, Mark DeNichilo, Delphine Merino, Claudine S. Bonder   +11 more
wiley   +1 more source

Fast Intra and Inter Prediction Mode Decision of H.264/AVC for Medical Image Compression Based on Region of Interest [PDF]

Journal of Intelligent Procedures in Electrical Technology, 2012
This paper aims at applying H.264 in medical video compression applications and improving the H.264 Compression performance with better perceptual quality and low coding complexity.
Mehdi Jafari, Homayoun Mahdavi-Nasab, Shohreh Kasaei   +2 more
doaj