Results 61 to 70 of about 1,607,083 (320)
This perspective highlights emerging insights into how the circadian transcription factor CLOCK:BMAL1 regulates chromatin architecture, cooperates with other transcription factors, and coordinates enhancer dynamics. We propose an updated framework for how circadian transcription factors operate within dynamic and multifactorial chromatin landscapes ...
Xinyu Y. Nie, Jerome S. Menet
wiley +1 more source
Protein pyrophosphorylation by inositol pyrophosphates — detection, function, and regulation
Protein pyrophosphorylation is an unusual signaling mechanism that was discovered two decades ago. It can be driven by inositol pyrophosphate messengers and influences various cellular processes. Herein, we summarize the research progress and challenges of this field, covering pathways found to be regulated by this posttranslational modification as ...
Sarah Lampe +3 more
wiley +1 more source
On Network Coding Capacity - Matroidal Networks and Network Capacity Regions [PDF]
One fundamental problem in the field of network coding is to determine the network coding capacity of networks under various network coding schemes. In this thesis, we address the problem with two approaches: matroidal networks and capacity regions. In
Kim, Anthony
core +2 more sources
Link-State Based Decode-Forward Schemes for Two-way Relaying
In this paper, we analyze a composite decode-and-forward scheme for the two-way relay channel with a direct link. During transmission, our scheme combines both block Markov coding and an independent coding scheme similar to network coding at the relay ...
Pinals, Lisa, Vu, Mai
core +1 more source
Function‐driven design of a surrogate interleukin‐2 receptor ligand
Interleukin (IL)‐2 signaling can be achieved and precisely fine‐tuned through the affinity, distance, and orientation of the heterodimeric receptors with their ligands. We designed a biased IL‐2 surrogate ligand that selectively promotes effector T and natural killer cell activation and differentiation. Interleukin (IL) receptors play a pivotal role in
Ziwei Tang +9 more
wiley +1 more source
The sequence of the Non-Coding Region (NCR) and Coding Region (CR) of 5’-terminal cRNA of thepolymerase basic 1 (PB1) gene as a major factor for the species adaptation of avian influenza virussubtype H5N1 (AIV H5N1) has been analysed.
Gusti Ayu Yuniati Kencana +3 more
doaj
The complete mitochondrial genome of the jewel beetle Trachys variolaris (Coleoptera: Buprestidae)
The complete mitochondrial genome (mitogenome) of the jewel beetle, Trachys variolaris, was sequenced and described. The mitogenome of T. variolaris is a typical circular DNA molecule with 16,771 bp in length.
Liangming Cao, Xiaoyi Wang
doaj +1 more source
Multilevel Diversity Coding Systems: Rate Regions, Codes, Computation, & Forbidden Minors
The rate regions of multilevel diversity coding systems (MDCS), a sub-class of the broader family of multi-source multi-sink networks with special structure, are investigated. After showing how to enumerate all non-isomorphic MDCS instances of a given size, the Shannon outer bound and several achievable inner bounds based on linear codes are given for ...
Congduan Li +2 more
openaire +2 more sources
Localization of tyrosine kinase-coding region in v-abl oncogene by the expression of v-abl-encoded proteins in bacteria [PDF]
A series of plasmids containing different segments of the v-abl oncogene have been constructed to express different portions of the v- abl protein in bacteria.
Baltimore, David, Wang, Jean Y. J.
core
Multiple ETS family transcription factors bind mutant p53 via distinct interaction regions
Mutant p53 gain‐of‐function is thought to be mediated by interaction with other transcription factors. We identify multiple ETS transcription factors that can bind mutant p53 and found that this interaction can be promoted by a PXXPP motif. ETS proteins that strongly bound mutant p53 were upregulated in ovarian cancer compared to ETS proteins that ...
Stephanie A. Metcalf +6 more
wiley +1 more source

