Results 71 to 80 of about 1,607,083 (320)

The newfound relationship between extrachromosomal DNAs and excised signal circles

open access: yesFEBS Letters, EarlyView.
Extrachromosomal DNAs (ecDNAs) contribute to the progression of many human cancers. In addition, circular DNA by‐products of V(D)J recombination, excised signal circles (ESCs), have roles in cancer progression but have largely been overlooked. In this Review, we explore the roles of ecDNAs and ESCs in cancer development, and highlight why these ...
Dylan Casey, Zeqian Gao, Joan Boyes
wiley   +1 more source

An upstream open reading frame regulates expression of the mitochondrial protein Slm35 and mitophagy flux

open access: yesFEBS Letters, EarlyView.
This study reveals how the mitochondrial protein Slm35 is regulated in Saccharomyces cerevisiae. The authors identify stress‐responsive DNA elements and two upstream open reading frames (uORFs) in the 5′ untranslated region of SLM35. One uORF restricts translation, and its mutation increases Slm35 protein levels and mitophagy.
Hernán Romo‐Casanueva   +5 more
wiley   +1 more source

In situ molecular organization and heterogeneity of the Legionella Dot/Icm T4SS

open access: yesFEBS Letters, EarlyView.
We present a nearly complete in situ model of the Legionella Dot/Icm type IV secretion system, revealing its central secretion channel and identifying new components. Using cryo‐electron tomography with AI‐based modeling, our work highlights the structure, variability, and mechanism of this complex nanomachine, advancing understanding of bacterial ...
Przemysław Dutka   +11 more
wiley   +1 more source

An Extended Network Coding Opportunity Discovery Scheme in Wireless Networks

open access: yes, 2012
Network coding is known as a promising approach to improve wireless network performance. How to discover the coding opportunity in relay nodes is really important for it.
Dong, Zhao   +4 more
core   +1 more source

The (Glg)ABCs of cyanobacteria: modelling of glycogen synthesis and functional divergence of glycogen synthases in Synechocystis sp. PCC 6803

open access: yesFEBS Letters, EarlyView.
We reconstituted Synechocystis glycogen synthesis in vitro from purified enzymes and showed that two GlgA isoenzymes produce glycogen with different architectures: GlgA1 yields denser, highly branched glycogen, whereas GlgA2 synthesizes longer, less‐branched chains.
Kenric Lee   +3 more
wiley   +1 more source

The complete mitochondrial genome of the Cyclemys fusca (Chelonia: Geoemydidae)

open access: yesMitochondrial DNA. Part B. Resources, 2018
The complete mitochondrial genome (mitogenome) of Cyclemys fusca was obtained and characterized in this study. The circular molecule is 16,491 bp in length and contained 13 protein-coding genes (PCGs), two ribosomal RNA (rRNA) genes, 22 transfer RNA ...
Meng Wang, Yuanhua Lu, Liuwang Nie
doaj   +1 more source

Searching the coding region for microRNA targets [PDF]

open access: yesRNA, 2013
Finding microRNA targets in the coding region is difficult due to the overwhelming signal encoding the amino acid sequence. Here, we introduce an algorithm (called PACCMIT-CDS) that finds potential microRNA targets within coding sequences by searching for conserved motifs that are complementary to the microRNA seed region and also overrepresented in ...
Ray M, Marín   +2 more
openaire   +2 more sources

A Generalized Channel Coding Theory for Distributed Communication

open access: yes, 2015
This paper presents generalized channel coding theorems for a time-slotted distributed communication system where a transmitter-receiver pair is communicating in parallel with other transmitters. Assume that the channel code of each transmitter is chosen
Luo, Jie
core   +1 more source

Characterizing the salivary RNA landscape to identify potential diagnostic, prognostic, and follow‐up biomarkers for breast cancer

open access: yesMolecular Oncology, EarlyView.
This study explores salivary RNA for breast cancer (BC) diagnosis, prognosis, and follow‐up. High‐throughput RNA sequencing identified distinct salivary RNA signatures, including novel transcripts, that differentiate BC from healthy controls, characterize histological and molecular subtypes, and indicate lymph node involvement.
Nicholas Rajan   +9 more
wiley   +1 more source

Region-of-Interest Based Coding Scheme for Live Videos

open access: yesApplied Sciences
In this paper, we introduce a novel rate control scheme specifically tailored for live broadcasting scenarios. Notably, in high-definition live transmissions of sports events and video game competitions that typically exceed 1080 p resolution and run at ...
Xiuxin Dou, Xixin Cao, Xianguo Zhang
doaj   +1 more source

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